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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | The MyD88-dependent ,but not the MyD88-independent,pathway of TLR4 signaling is important in clearing Nontypeable Haemophilus influenzae from the mouse lung 显示文摘 | Catharina W Sandrine F Nico A | 2005 | J Immunol2005，175，： | 1 |
| 3 | Information support, equity and burnout: The moderating effect of self-efficacy显示文摘 | Nico W Van Yperen | 1998 | Journal of Occupational and Organizational and Psychology1998，1，： | 1 |
| 4 | Reliability of stroke volume to pulse pressure ratio for estimating and detecting changes in arterial compliance显示文摘 | OTELIO SR NICO W GERARD CB etal | 1986 | J Hypertens1986，4，5： | 1 |
| 5 | Performance-based pay is fair,partic-ularly when I perform better:differential fairness per-ceptions of allocators and recipients显示文摘 | Nico W Van Y | 2005 | European Jour-nal of Social Psychology2005，35，： | 1 |
| 6 | A longitudinal study of equity andsatisfaction in intimate relationships显示文摘 | Nico W VanYperen Bram P B | 1990 | European Journal of SocialPsychology1990，20，4： | 1 |
| 7 | On the Regularity of Semidirect Products显示文摘 | Nico W R | 1983 | Journal of Algebra1983，80，1： | 1 |
| 8 | Use of Micro-XANES to speciate chromium in airborne fine particles in the sacramento valley显示文摘 | Michellel W Peters Nico M | 2007 | Environmental Science & Technology2007，41，： | 1 |
| 9 | Go with the Flow: Conforming to Others in the Face of Existential Threat 显示文摘 | Lennart J Renkema Diederik A Stapel Nico W Van Yperen | 2008 | European Journal of Social Psychology2008，38，： | 1 |
| 10 | On the regularity of semidirect products sem-igroups 显示文摘 | Nico W R | 1993 | Journal of Algebra1993，80，： | 1 |
| 11 | Incorporating the real estate cycle intomanagement decisions-evidence from Germany显示文摘 | NICO R | 2004 | Real Estate Portfolio Management2004，3，10： | 1 |
| 12 | Employees' Goal Orientations, the Quality of Leader- member Exchange, and the Outcomes of Job Performance and Job Satisfaction显示文摘 | ONNE JANSSEN NICO W VAN YPEREN | 2004 | Academy of Management Journal2004，，： | 1 |
| 13 | Contrasting time trends of organic contaminants in Antarctic pelagic and benthic food webs 显示文摘 | Van den Brink Nico W Riddle Martin J Van den Heuvel-Greve Martine Van Fnmeker Jan Andries | 2011 | Marine Pollution Bulletin2011，62，1： | 1 |
| 14 | Evaluation of nested PCR DGGE (denaturing gradient gel electrophoresis) with group specific 16S sRNA primers for the analysis of bacterial communities from different wastewater treatment plants显示文摘 | Nico B Wim D. W Willy V | | 0，，： | 1 |
| 15 | Effect of ni- trification inhibitors on the growth and activity of Nitrosotalea de- vanaterra in culture and soil 显示文摘 | Lehtovirta-Morley L E Verhamme D T Nico! G W | 2013 | Soil Biology and Biochemistry2013，62，： | 1 |
| 16 | Burnout and depression are not identi- cal twins:is decline of superiority a distinguishing feature? 显示文摘 | VEERLE BRENNINKMEYER NICO W VAN YPEREN BRAM P BUUNK | 2001 | Personality and Individual Differences2001，30，： | 1 |
| 17 | Employees' goal orientations, the quality of leader-member exchange, and the outcomes of job performance and satisfaction显示文摘 | Janssen Onne Van Yperen Nico W | 2004 | Academy of Management Journal2004，47，3： | 1 |
| 18 | On the regularity of semidirect product 显示文摘 | Nico W R | 1983 | J Algebra1983，80，： | 1 |
| 19 | on the regularity of semidirect products显示文摘 | Nico W R | 1983 | J Algebra1983，80，： | 1 |
| 20 | Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study显示文摘 | Elira M Nico W Berend E et a/ | 2016 | Plos One2016，11，6： | 1 |
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