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| 1 | Characterization of lipid parameters in diabetic and non-diabetic atherosclerotic patients显示文摘背景 &在类脂化合物侧面不安和糖尿病之间的 ObjectiveThe 关系联系了复杂并发症长是兴趣的一个区域。Dyslipidemia 在糖尿病的病人是心血管的病态和死亡的一个有势力预言者。现在的学习的目的是在百和 76 个个人(45-75 年年龄) 参予了的糖尿病、非糖尿病的动脉粥样硬化患者 patients.MethodsFive 调查在老化和类脂化合物侧面之间的关系这研究。在这些之中, 192 正在有糖尿病 mellitus 和动脉粥样硬化的历史。个人们在健康的底上被分类(正常、非糖尿病的动脉粥样硬化,糖尿病的动脉粥样硬化) 并且年龄(45-55 年, 56-65 年,和 66-75 年) 。所有参加者受到象详细历史一样的过程,为 fasting 血糖的生物化学的分析,血红素 A1c,全部的胆固醇(TC ) , triglycerides (TG ) ,低密度的脂蛋白 --(LDL ) ,很低密度的脂蛋白(VLDL ) 和高密度的脂蛋白(HDL ) 。所有这些参数在所有三个年龄组的糖尿病、非糖尿病的动脉粥样硬化患者病人之间被比较。TC/HDL 和 LDL/HDL 也是有的 calculated.ResultsDiabetic 动脉粥样硬化患者个人(男性和女性) 与非糖尿病的动脉粥样硬化患者和正常控制个人相比的 HDL 的 TC, TG, LDL, VLDL 和底层高级。在所有三个年龄组之中,脂蛋白反常被观察比男性在女性更经常。在与年龄相比的糖尿病的动脉粥样硬化患者题目 TC/HDL 和 LDL/HDL 比率有重要增加,性别随两性的年龄的增加匹配非糖尿病的动脉粥样硬化患者和 dyslipidemia 增加的正常 control.ConclusionsDegree。女性是对糖尿病的 dyslipidemia 敏感的更多并且因此有与增加年龄开发动脉粥样硬化的更多的风险。 | Fatima Ali Hassan Jamil Sanam Saiqa Anwar Nadia Wajid | 2015 | Journal of Geriatric Cardiology2015，12，1： | 6 |
| 2 | Extensive evolution analysis of the global chikungunya virus strains revealed the origination of CHIKV epidemics in Pakistan in 2016显示文摘Chikungunya virus(CHIKV) is a mosquito-borne virus that causes epidemics widely in the world especially in the tropical and subtropical regions. Phylogenetic analysis has found that the CHIKV lineages were associated with the spatial and temporal distributions, which were related to the virus adaption to the major mosquito species and their distributions. In this study, we reported the complete genome sequences of eight CHIKV isolates from the outbreak in Pakistan last year. Then we reviewed the evolutionary history using extensive phylogenetic analysis, analyzed lineagespecific substitutions in viral proteins, and characterized the spreading pathway of CHIKV strains including the Pakistani strains. The results showed that the Pakistani stains belonged to the ECSA.IOL sub-lineage and derived from India. The genetic properties of the Pakistani strains including the adaptive substitution to vectors were further characterized, and the potential risks from the occurrence of CHIKV infection in Pakistan were discussed. These results provided better understanding of CHIKV evolution and transmission in the world and revealed the possible origination of the CHIKV outbreak and epidemic in Pakistan, which would promote the disease prevention and control in the identified countries and territories with the history of CHIKV infections as well as new regions with potential risk of CHIKV outbreaks. | Junming Shi Zhengyuan Su Zhaojun Fan Jun Wang Siqing Liu Bo Zhang Hongping Wei Shoukat Jehan Nadia Jamil Shu Shen Fei Deng | 2017 | Virologica Sinica2017，32，6： | 2 |
| 3 | Forced migration of soluble and suspended materials by freezing front in aqueous systems显示文摘 | Umer Shafique Jamil Anwar Waheed uz-Zaman Rabia Rehman Muhammad Salman Amara Dar Nadia Jamil | 2011 | Journal of Hydro-environment Research2011，，3： | 1 |
| 4 | Detection, isolation, and characterization of chikungunya viruses associated with the Pakistan outbreak of 2016–2017显示文摘The chikungunya virus(CHIKV) is a mosquito-transmitted alphavirus, which has infected millions of people in Africa, Asia, Americas, and Europe since it reemerged in India and Indian Ocean regions in 2005–2006. Starting in the middle of November 2016, CHIKV has been widely spread, and more than 4,000 cases of infections in humans were confirmed in Pakistan. Here, we report the first isolation and characterization of CHIKV from the Pakistan outbreak. Eight CHIKV strains were newly isolated from human serum samples using a cell culture procedure. A full-length genome sequence and eight complete envelope(E1) sequences of CHIKV from Pakistan were obtained in this study. Alignment of the CHIKV E1 sequences revealed that the eight new CHIKV isolates were highly homogeneous, with only two nonsynonymous substitutions found at generally conserved sites(E99 and Q235). Based on the comparison of 342 E1 sequences, the two nonsynonymous mutations were located in well-recognized domains associated with viral functions such as the cell fusion and vector specificity, suggesting their potential functional importance. Phylogenetic analysis indicated that the CHIKV strains from Pakistan originated from CHIKV circulating in the Indian region. This study helps elucidate the epidemics of CHIKV in Pakistan and also provides a foundation for studies of evolution and expansion of CHIKV in South Asia. | Si-Qinq Liu Xiao Li Ya-Nan Zhang Ai-Li Gao Cheng-Lin Deng Jun-Hua Li Shoukat Jehan Nadia Jamil Fei Deng Hongping Wei Bo Zhang | 2017 | Virologica Sinica2017，32，6： | 0 |
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