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| 1 | Natural mutations lead to enhanced proteasomal degradation of human Ncb5or, a novel flavoheme reductase显示文摘 | Fanni S. Kálmán Beáta Lizák Szilvia K. Nagy Tamás Mészáros Veronika Zámbó József Mandl Miklós Csala éva Kereszturi | 2013 | Biochimie2013，，7： | 1 |
| 2 | Analysis of risk factors-especially different types of plexitis-for postoperative relapse in Crohn's disease显示文摘AIM To evaluate the presence of submucosal and myenteric plexitis and its role in predicting postoperative recurrence.METHODS Data from all patients who underwent Crohn's disease(CD)-related resection at the University of Szeged, Hungary between 2004 and 2014 were analyzed retrospectively. Demographic data, smoking habits, previous resection, treatment before and after surgery, resection margins, neural fiber hyperplasia, submucosal and myenteric plexitis were evaluated as possible predictors of postoperative recurrence. Histological samples were analyzed blinded to the postoperative outcome and the clinical history of the patient. Plexitis was evaluated based on the appearance of the most severely inflamed ganglion or nerve bundle. Patients underwent regular follow-up with colonoscopy after surgery. Postoperativerecurrence was defined on the basis of endoscopic and clinical findings, and/or the need for additional surgical resection. RESULTS One hundred and four patients were enrolled in the study. Ileocecal, colonic, and small bowel resection were performed in 73.1%, 22.1% and 4.8% of the cases, respectively. Mean disease duration at the time of surgery was 6.25 years. Twenty-six patients underwent previous CD-related surgery. Forty-three point two percent of the patients were on 5-aminosalicylate, 20% on corticosteroid, 68.3% on immunomodulant, and 4% on anti-tumor necrosis factor-alpha postoperative treatment. Postoperative recurrence occurred in 61.5% of the patients; of them 39.1% had surgical recurrence. 92.2% of the recurrences developed within the first five years after the index surgery. Mean disease duration for endoscopic relapse was 2.19 years. The severity of submucosal plexitis was a predictor of the need for second surgery(OR = 1.267, 95%CI: 1.000-1.606, P = 0.050). Female gender(OR = 2.21, 95%CI: 0.98-5.00, P = 0.056), stricturing disease behavior(OR = 3.584, 95%CI: 1.344-9.559, P = 0.011), and isolated ileal localization(OR = 2.671, 95%CI: 1.033-6.910, P = 0.043) were also predictors of postoperative recurrence. No association was revealed between postoperative recurrence and smoking status, postoperative prophylactic treatment and the presence of myenteric plexitis and relapse.CONCLUSION The presence of severe submucosal plexitis with lymphocytes in the proximal resection margin is more likely to result in postoperative relapse in CD. | Agnes Milassin Anita Sejben László Tiszlavicz Zita Reisz Gyorgy Lázár Mónika Szucs Renáta Bor Anita Bálint Mariann Rutka Zoltán Szepes Ferenc Nagy Klaudia Farkas Tamás Molnár | 2017 | World Journal of Gastrointestinal Surgery2017，9，7： | 1 |
| 3 | Heterogeneity of angiogenic response induced in different normal aduh tissues by vascular permeability factor/vascular endothelial growth factor显示文摘 | Pmersson A Nagy TA BrownL F | 2000 | J Clin Invest2000，80，1： | 1 |
| 4 | Vasuclar permeability factor (vascular endothelial growth factor) in guinea pig and human tumor and inflammatory effusions显示文摘 | Wang HH Nagy TA | 1993 | Cancer Res1993，53，12： | 1 |
| 5 | β- Catenin and p120 me- diate PPARS-dependcnt proliferation induced by helicobacter pylo- ri in human and rodent epithelia显示文摘 | Nagy TA Wroblewski LE Wang D | 2011 | Gastroenterology2011，141，2： | 1 |
| 6 | Regulation of p53 tumorsuppressor by Helicobacter pylori in gastric epithelial cells 显示文摘 | Wei J Nagy TA Vilgelm A | 2010 | Gastroenterology2010，139，4： | 1 |
| 7 | IC31,a two-component novel adjuvant mixed with a conjugate vaccine enhances protective immunity against pneumococcal disease in neonatal mice显示文摘 | Olafsdottir TA Lingnau K Nagy E | 2009 | Scand J Immunol2009，69，3： | 1 |
| 8 | Examination of the Illness Representations among Children with T1DM in Relation to Mental Health Factors显示文摘The most common comorbid psychiatric disorders in children with type 1 diabetes mellitus(T1DM)are depression,anxiety and behavioral disorders.Patients with comorbid psychopathology are less capable of psychically adjusting to the new life situation resulting from T1DM,which may negatively affect glycemic control and adherence related to the treatment.We aimed to investigate the association between mental health and type 1 diabetes including illness representation.115 children and adolescents with T1DM were recruited through the outpatient clinic in Debrecen,Hungary.Measures:PRISM-D,Child Depression Inventory(CDI),Cantril Ladder and Self-Rated Health,Glycosylaeted haemoglobin(HbA1C)were measured.Children having depressive symptoms drew fewer circles with less area.Children not drawing any important relationships possessed more depressive symptoms.Those diagnosed at a younger age displayed smaller distance between the Self-and Illness-circles.The PRISM-D test can be a promising tool to analyse emotional and cognitive representations and the psychological burden of T1DM. | Brigitta Munkácsi EnikőFelszeghy Flóra Kenyhercz Beáta Erika Nagy | 2023 | International Journal of Mental Health Promotion2023，25，8： | 0 |
| 9 | Neurodevelopmental in Relation to Breastfeeding–Experiences among Hungarian Preterm Infants at 12 Months of Corrected Age:Empirical Study显示文摘Preterm and low birth weight infants are at higher risk of neurodevelopmental outcomes;breastfeeding offers sev-eral beneficial aspects for them.This study aimed to describe the average neurodevelopmental outcomes of pre-term infants and examine the associations between neurodevelopment and breastfeeding among Hungarian preterm infants at 12 months of corrected age.154 preterm infants with low birth weight(<2500 g)and their mothers were participated in this study.Bayley-III Screening Test(Bayley Scales of Infant and Toddler Develop-ment Screening Test,Third Edition)was administered to measure the cognitive,language and motor skills of infants;breastfeeding data was obtained through parental anamnesis.To analyze data,independent sample t-test or the Welch t-test,Mann-Whitney tests,Chi-square tests of independence and Spearman’s rank correlation test were used to.Concerning the risk of developmental delay,Receptive and Expressive language and Fine motor subscales were the lowest.Examination of the associations between breastfeeding and neurodevelopmental per-formance identified significantly higher cognitive(U=2047.5;P=0.023)andfine motor(U=2096.0;P=0.037)skills in infants who were breastfed.We found significant positive correlations between the duration of breastfeeding and cognitive,expressive language andfine motor skills.The study draws the attention to the importance of breastfeeding and early screening.Further research is required to examine the casual relationship between neurodevelopmental outcomes and breastfeeding. | Anna Szabina Szele Beáta Erika Nagy | 2022 | International Journal of Mental Health Promotion2022，24，5： | 0 |
| 10 | Effect of quantum therapy on pork quality显示文摘In this study the impact of quantum therapy on meat quality of slaughtered pigs was investigated.For this purpose the pigs were treated with different doses of magnet-infrared-laser(MIL) radiation.Animals were divided into four groups according to radiation doses(4096,512,and 64 Hz,and control without application),which were applied in the lumbar area of musculus longissimus dorsi(loin) at various time intervals prior to the slaughter(14 d,24 h,and 1 h).Animals were slaughtered and the meat quality was evaluated by determining of pH value(1,3,and 24 h post slaughter),drip loss,colour,and lactic acid and phosphoric acid amounts.MIL therapy can be used in various fields of veterinary medicine as are surgery and orthopaedics,internal medicine,dentistry,pulmonology,gastroenterology,gynaecology,urology,nephrology,and dermatology.The results achieved showed that MIL radiation used in a short period before slaughter(1 h) can cause a change in the meat quality,as reflected by the non-standard development of pH values,increases in drip loss,and changes of meat colour. | Martin BODNáR Jozef NAGY Peter POPELKA Beáta KORéNEKOVá Ján MAANGA Alena NAGYOVá | 2011 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，11： | 0 |
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