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| 1 | Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors显示文摘 | Daniela C. Kroy Donatella Ciuffreda Jennifer H. Cooperrider Michelle Tomlinson Garrett D. Hauck Jasneet Aneja Christoph Berger David Wolski Mary Carrington E. John Wherry Raymond T. Chung Kenneth K. Tanabe Nahel Elias Gordon J. Freeman Rosemarie H. de Kru | 2014 | Gastroenterology2014,,2: | 2 |
| 2 | Carbonyl reduction of an anti-inset agent imidazole analogue of metyrapone in soil bacteria,invertebrate and vertebrate species显示文摘 | OPPERMANN U C T NAHEL G BELAI L | 1998 | Chemico-Biolodical Inter1998,,114: | 1 |
| 3 | The Current Role of Ultrasound Use in Teaching Regional Anesthesia: A Survey of Residency Programs in the United States显示文摘 | Mohammad A. Helwani Nahel N. Saied Bassem Asaad Stephanie Rasmussen Mitchell E. Fingerman | 2012 | Pain Medicine2012,,10: | 1 |
| 4 | Car- bonyl reduction of an anti-inset agent imidazolc analogue of metyrapone in soil bacteria, invertebrate and vertebrate species 显示文摘 | OPPERMANN U C T NAHEL G BELAI L | 1998 | Chemico-Biolodical Inter1998,114,: | 1 |
| 5 | Laparoscopic vs open donor nephrectomy:Lessons learnt from single academic center experience显示文摘AIM To compare laparoscopic and open living donor nephrectomy,based on the results from a single center during a decade.METHODS This is a retrospective review of all living donor nephrectomies performed at the Massachusetts General Hospital,Harvard Medical School,Boston,between 1/1998- 12/2009. Overall there were 490 living donors,with 279 undergoing laparoscopic living donor nephrectomy(LLDN) and 211 undergoing open donor nephrectomy(OLDN). Demographic data,operating room time,the effect of the learning curve,the number of conversions from laparoscopic to open surgery,donor preoperative glomerular filtration rate and creatinine(Cr),donor and recipient postoperative Cr,delayed graft function and donor complications were analyzed. Statistical analysis was performed.RESULTS Overall there was no statistically significant difference between the LLDN and the OLDN groups regarding operating time,donor preoperative renal function,donor and recipient postoperative kidney function,delayed graft function or the incidence of major complications. When the last 100 laparoscopic cases were analyzed,there was a statistically significant difference regarding operating time in favor of the LLDN,pointing out the importance of the learning curve. Furthermore,another significant difference between the two groups was the decreased length of stay for the LLDN(2.87 d for LLDN vs 3.6 d for OLDN).CONCLUSION Recognizing the importance of the learning curve,this paper provides evidence that LLDN has a safety profile comparable to OLDN and decreased length of stay for the donor. | Georgios Tsoulfas Polyxeni Agorastou Dicken SC Ko Martin Hertl Nahel Elias AB Cosimi Tatsuo Kawai | 2017 | World Journal of Nephrology2017,6,1: | 1 |
| 6 | Dissociation between stem cell phenotype and NOD/SCID repopulating activity in human peripheral blood CD34+ cells after ex vivo expansion显示文摘 | Guénahel H Danet Hubert W Lee Jennifer L Luongo | 2001 | Exp Hematol2001,29,12: | 1 |
| 7 | Hyperlipidemia due to Biliary Stricture After Living-Donor Liver Transplantation显示文摘 | Heidi Yeh William H. Kitchens Nahel Elias Peter B. Kelsey James F. Markmann Martin Hertl | 2011 | Transplantation2011,,6: | 1 |
| 8 | Ebola virus secretory glycoprotein (sGP) diminishes Fc gamma RⅢB-to-CR3 proximity on neutrophils显示文摘 | Kindzelskii A L Yang Z Nahel G J Todd R F 3rd Petty H R | 2000 | J Immunol2000,164,: | 1 |
| 9 | Carbonyl reduction of an anti-inset agent imidazole analogue of metyrapone in soil bacteria,invertebrate and vertebrate species显示文摘 | OPPERMANN U C T NAHEL G BELAI I | 1998 | Chemico-Biolodical Inter1998,114,: | 1 |
| 10 | Carbonyl reduction of an anti-inset agent imidazole analogue of metronome in soil bacteria, invertebrate and vertebrate species显示文摘 | Oppermann U C T Nahel G Belai I | 1998 | Chemico- Biolodical Inter1998,114,: | 1 |
| 11 | Analysis of the effects of donor and recipient hepatitis C infection on kidney transplant outcomes in the United States显示文摘BACKGROUND As Hepatitis C virus infection(HCV+)rates in kidney donors and transplant recipients rise,direct-acting antivirals(DAA)may affect outcomes.AIM To analyze the effects of HCV+in donors,recipients,or both,on deceased-donor(DD)kidney transplantation(KT)outcomes,and the impact of DAAs on those effects.METHODS The Organ Procurement and Transplantation Network data of adult first solitary DD-KT recipients 1994-2019 were allocated into four groups by donor and recipient HCV+status.We performed patient survival(PS)and death-censored graft survival(DCGS)pairwise comparisons after propensity score matching to assess the effects of HCV+in donors and/or recipients,stratifying our study by DAA era to evaluate potential effect modification.RESULTS Pre-DAA,for HCV+recipients,receiving an HCV+kidney was associated with 1.28-fold higher mortality(HR 1.151.281.42)and 1.22-fold higher death-censored graft failure(HR 1.081.221.39)compared to receiving an HCV-kidney and the absolute risk difference was 3.3%(95%CI:1.8%-4.7%)for PS and 3.1%(95%CI:1.2%-5%)for DCGS at 3 years.The HCV dual-infection(donor plus recipient)group had worse PS(0.56-fold)and DCGS(0.71-fold)than the dual-uninfected.Donor HCV+derived worse post-transplant outcomes than recipient HCV+(PS 0.36-fold,DCGS 0.34-fold).In the DAA era,the risk associated with HCV+in donors and/or recipients was no longer statistically significant,except for impaired PS in the dual-infected vs dual-uninfected(0.43-fold).CONCLUSION Prior to DAA introduction,donor HCV+negatively influenced kidney transplant outcomes in all recipients,while recipient infection only relatively impaired outcomes for uninfected donors.These adverse effects disappeared with the introduction of DAA. | Qing Yuan Shanjuan Hong Gregory Leya Eve Roth Georgios Tsoulfas WW Williams Joren C Madsen Nahel Elias | 2023 | World Journal of Transplantation2023,13,2: | 0 |