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| 1 | Risk factors and classifications of hilar cholangiocarcinoma显示文摘Cholangiocarcinoma is the second most common primary malignant tumor of the liver.Perihilar cholangiocarcinoma or Klatskin tumor represents more than 50% of all biliary tract cholangiocarcinomas.A wide range of risk factors have been identified among patients with Perihilar cholangiocarcinoma including advanced age,male gender,primary sclerosing cholangitis,choledochal cysts,cholelithiasis,cholecystitis,parasitic infection(Opisthorchis viverrini and Clonorchis sinensis),inflammatory bowel disease,alcoholic cirrhosis,nonalcoholic cirrhosis,chronic pancreatitis and metabolic syndrome.Various classifications have been used to describe the pathologic and radiologic appearance of cholangiocarcinoma.The three systems most commonly used to evaluate Perihilar cholangiocarcinoma are the Bismuth-Corlette(BC) system,the Memorial Sloan-Kettering Cancer Center and the TNM classification.The BC classification provides preoperative assessment of local spread.The Memorial Sloan-Kettering cancer center proposes a staging system according to three factors related to local tumor extent:the location and extent of bile duct involvement,the presence or absence of portal venous invasion,and the presence or absence of hepatic lobar atrophy.The TNM classification,besides the usual descriptors,tumor,node and metastases,provides additional information concerning the possibility for the residual tumor(R) and the histological grade(G).Recently,in 2011,a new consensus classification for the Perihilar cholangiocarcinoma had been published.The consensus was organised by the European Hepato-PancreatoBiliary Association which identified the need for a new staging system for this type of tumors.The classification includes information concerning biliary or vascular(portal or arterial) involvement,lymph node status or metastases,but also other essential aspects related to the surgical risk,such as remnant hepatic volume or the possibility of underlying disease. | Miguel Angel Suarez-Munoz Jose Luis Fernandez-Aguilar Belinda Sanchez-Perez Jose Antonio Perez-Daga Beatriz Garcia-Albiach Ysabel Pulido-Roa Naiara Marin-Camero Julio Santoyo-Santoyo | 2013 | World Journal of Gastrointestinal Oncology2013，5，7： | 23 |
| 2 | Terrain radiometric calibration of airborne UAVSAR for forested area显示文摘In the field of biomass estimation,terrain radiometric calibration of airborne polarimetric SAR data for forested areas is an urgent problem.Illuminated area correction ofσ-naught could not completely remove terrain features.Inspired by Small and Shimada,this paper tested gamma-naught on one mountainous forested area using airborne Uninhabited Aerial Vehicle Synthetic Aperture Radar data and found it could remove most terrain features.However,a systematic increasing trend from far range to near range is found in airborne SAR cases.This paper made an attempt to use the relationship between distance to SAR sensor andγ-naught to calibrateγ-naught.Two quantitative evaluation methods are proposed.Experimental results demonstrate that variation ofγ-naught can be constrained to a limited extent from near range to far range.Since this method is based on ground range images,it avoids complicated orthorectification. | CHENG Xiaoguang Naiara PINTO GONG Jianya | 2012 | Geo-Spatial Information Science2012，15，4： | 2 |
| 3 | The extraction of an- thocyanins and proanthocyanidins from grapes to wine during fermenta- tive maceration is affected by the enological technique 显示文摘 | NAIARA B V ENCARNA G P JOSE L R | 2011 | J Agr Food Chem2011，59，10： | 1 |
| 4 | The Key Role of Human Resource Practices for the Promotion of Creativity and Innovation: A Spanish Case Study显示文摘 | Naiara Escriba-Carda Maria Teresa Canet-Giner Francisco Balbastre-Benavent | 2013 | Management Innovation2013，，10： | 1 |
| 5 | The activity and expression of NTPDase is altered in lymphocytes of multiple sclerosis patients显示文摘 | Roselia M. Spanevello Cinthia M. Mazzanti Roberta Schmatz Gustavo Thomé Margarete Bagatini Maisa Correa Cintia Rosa Naiara Stefanello Luziane Potrich Bellé Maria B. Moretto Liliane Oliveira Vera M. Morsch Maria R.C. Schetinger | 2009 | Clinica Chimica Acta2009，，3： | 1 |
| 6 | ERK2 protein regulates the proliferation of human mesenchymal stem cells without affecting their mobilization and differentiation potential显示文摘 | Iván Cárcamo-Orive Naiara Tejados Jesús Delgado Ainhoa Gaztelumendi David Otaegui Valerie Lang César Trigueros | 2008 | Experimental Cell Research2008，，8： | 1 |
| 7 | NiWO4 powders prepared via polymeric precursor method for application as ceramic luminescent pigments显示文摘Ni WO4 was prepared using the polymeric precursor method and studied in terms of physical and chemical properties to verify its stability for industrial applications as pigments.The characterization was accomplished using thermal analyses,X-ray diffraction(XRD),scanning electron microscopy(SEM),photoluminescence(PL)and UV–Vis spectroscopies,colorimetric coordinates,and Raman spectra.Increasing the temperature,successive exothermic reactions were observed and they are related with thermal decomposition of the organic compound.The stability was reached at^700℃.The material is verified to become completely free of second phase at^800℃.The end Ni WO4 powders showed an intense charge transfer(CT)-related tail centered in the ultraviolet region,resulting in a yellow product.In addition,the powders exhibited broad excitation band and broad deep blue–green emission band,which were enhanced with increasing powders’crystallinity. | Naiara A.LIMA Lorena D.S.ALENCAR Máximo SIU-LI Carlos A.C.FEITOSA Alexandre MESQUITA Jean-Claude M’PEKO Maria I.B.BERNARDI | 2020 | Journal of Advanced Ceramics2020，9，1： | 1 |
| 8 | Demecolcine effects on microtubule kinetics and on chemically assisted enucleation of bovine oocytes显示文摘 | Naiara Z S Felipe P Simone C M | 2009 | Cloning Stem Cells2009，43，： | 1 |
| 9 | Of mice and NASH – from fat to inflammation and fibrosis显示文摘 | Hermann E. Wasmuth Mirko Moreno Zaldivar Naiara Beraza Christian Trautwein | 2007 | Drug Discovery Today: Disease Models2007，，1： | 1 |
| 10 | Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression显示文摘 | Fernando Vidal-Vanaclocha Lorea Mendoza Naiara Telleria Clarisa Salado María Valcárcel Natalia Gallot Teresa Carrascal Eider Egilegor Jabier Beaskoetxea Charles A. Dinarello | 2006 | Cancer and Metastasis Reviews2006，，3： | 1 |
| 11 | Atrial Fibrillation Catheter Ablation Versus Surgical Ablation Treatment (FAST): A 2-Center Randomized Clinical Trial显示文摘 | Lucas V.A. Boersma Manuel Castella WimJan van Boven Antonio Berruezo Alaaddin Yilmaz Mercedes Nadal Elena Sandoval Naiara Calvo Josep Brugada Johannes Kelder Maurits Wijffels Lluís Mont | 2012 | Circulation2012，，1： | 1 |
| 12 | Histone acetylation and its role in embryonic stem cell differentiation显示文摘The understanding of mechanisms leading to cellular differentiation is the main aim of numerous studies.Accessibility of DNA to transcription factors depends on local chromatin structure and chromatin compaction inhibits gene transcription.Histone acetylation correlates with an open chromatin structure and increased gene expression.Gene transcription levels are changed in early embryonic stem cells differentiation in a tissuespecific manner and epigenetic marks are modified,including increased global acetylation levels.Manipulation of histone deacetylases activity might be an interesting tool to generate populations of specific cell types for transplantation purposes.Thus,this review aims to show recent findings on histone acetylation,a post translational modif ication and its manipulation in embryonic stem cells differentiation. | Naiara Z Saraiva Clara S Oliveira Joaquim M Garcia | 2010 | World Journal of Stem Cells2010，2，6： | 1 |
| 13 | The extraction of anthocyanins and proanthocyanidins from grapes to wine during fermentative maceration is affected by the enological technique显示文摘 | Naiara B V Encarna G P Jose L R | 2011 | Journal of Agricultural and Food Chemistry2011，59，10： | 1 |
| 14 | Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma显示文摘 | Tom Luedde Naiara Beraza Vasileios Kotsikoris Geert van Loo Arianna Nenci Rita De Vos Tania Roskams Christian Trautwein Manolis Pasparakis | 2007 | Cancer Cell2007，，2： | 1 |
| 15 | Simultaneous analysis of the intestinal parasites and diet through eDNA metabarcoding显示文摘Agricultural expansion and intensification are having a huge impact on plant and arthropod diversity and abun-dance,affecting food availability for farmland birds.Difficult food access,in turn,can lead to immunosuppression and a higher incidence of parasites.In the studies designed to examine changes in the diet of birds and their par-asites,metabarcoding is proving particularly useful.This technique requires mini-barcodes capable of amplifying the DNA of target organisms from fecal environmental DNA.To help to understand the impact of agricultural expansion on biodiversity,this study sought to design and identify mini-barcodes that might simultaneously as-sess diet and intestinal parasites from the feces of farmland birds.The capacity to identify diet and parasites of 2 existing and 3 newly developed mini-barcodes was tested“in silico”in relation to the behavior of a reference eukaryotic barcode.Among the newly designed mini-barcodes,MiniB18S_81 showed the higher taxonomic cover-age of eukaryotic taxa and a greater amplification and identification capacity for diet and parasite taxa.Moreover,when it was tested on fecal samples from 5 different steppe bird species,MiniB18S_81 showed high taxonomic resolution of the most relevant diet and parasite phyla,Arthropoda,Nematoda,Platyhelminthes,and Apicomplexa at the order level.Thus,the mini-barcode developed emerges as an excellent tool to simultaneously provide detailed information regarding the diet and parasites of birds,essential for conservation and management. | Xabier CABODEVILLA Benjamín Juan GÓMEZ-MOLINER Naiara ABAD María JoséMADEIRA | 2023 | Integrative Zoology2023，18，3： | 1 |
| 16 | Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression显示文摘 | Fernando Vidal-Vanaclocha Lorea Mendoza Naiara Telleria Clarisa Salado María Valcárcel Natalia Gallot Teresa Carrascal Eider Egilegor Jabier Beaskoetxea Charles A. Dinarello | 2006 | Cancer and Metastasis Reviews2006，，3： | 1 |
| 17 | Improved outcomes and complications of atrial fibrillation catheter ablation over time:learning curve,techniques,and methodology显示文摘 | Naiara Calvo MercèNadal Antonio Berruezo | 2011 | Revista Espa de Cardiologia2011，65，2： | 1 |
| 18 | Agnuside Reduces Visceral Adipocyte Size,Improves Insulin Sensitivity and Reverses Hepatic Steatosis in Ovariectomized Rats显示文摘This study aimed to investigate the effects of agnuside(AGN),a phytoestrogen in Vitex agnus-castus,on cellular and metabolic alterations induced by ovariectomy in rats.Ovariectomized(OVX)Wistar rats were used as an animal model of postmenopausal metabolic syndrome.The visceral and subcutaneous adipocyte sizes,the peripheral insulin sensitivity and the occurrence of nonalcoholic fatty liver disease(NAFLD)and liver oxidative damage were evaluated.The results were compared with those obtained from control rats(sham-operated)and OVX rats treated daily with AGN.Obese OVX rats exhibited visceral adipocyte hypertrophy and developed glucose intolerance,hyperinsulinemia,NAFLD and dyslipidemia.AGN exerted beneficial effects on several metabolic parameters in OVX rats,including the improvement in glucose intolerance,hyperinsulinemia and NAFLD.Besides,AGN promoted a general improvement in the liver redox state.Although the reduction of the mesenteric adipocyte size is very likely to be an important mode of action of AGN,some actions of AGN could also involve the interaction with estrogen receptors. | Franciele Neves Moreno Eduardo Hideo Gilglioni Rosangela Fernandes Garcia Naiara Cristina Lucredi Sandra Mara Ferreira Nilton Almeida Brito Marcia do Nascimento Brito Emy Luiza Ishii-Iwamoto Clairce Luzia Salgueiro-Pagadigorria | 2019 | Journal of Pharmacy and Pharmacology2019，7，4： | 0 |
| 19 | Factors related to compliance with the COVID-19 health regulations among young people显示文摘The coronavirus pandemic has affected all facets of our lives and all ages and social strata worldwide.Measures have been taken to protect against the spread of the virus,such as more rigorous hand hygiene,the use of face masks and social distancing.However,the focus has often been on young people,who have been seen as a group lacking sufficient respect for government-imposed measures.This review outlines the preventive measures that have been taken in different countries and discusses their specific impact on young people and adolescents,taking into account the developmental stage and concrete needs of this age group.It summarizes those studies that have provided information on compliance with preventive measures by young people and adolescents,concluding that although compliance levels among this age group are lower than among older adults,the general view of youths as non-compliant is not consistent with real,objective data.The review also summarizes different views regarding the possible reasons for this lower level of compliance,taking into account both social(gender and age)and personal factors(personality,empathy,prosociality,self-control,cognitive styles and motivations),and discusses the practical implications of these findings for the future. | Joana Jaureguizar Iratxe Redondo Nuria Galende Naiara Ozamiz | 2021 | World Journal of Psychiatry2021，11，12： | 0 |
| 20 | Modelling policy combinations of vaccination and transmission suppression of SARS-CoV-2 in Rio de Janeiro,Brazil显示文摘COVID-19 vaccination in Brazil required a phased program,with priorities for age groups,health workers,and vulnerable people.Social distancing and isolation interventions have been essential to mitigate the advance of the pandemic in several countries.We developed a mathematical model capable of capturing the dynamics of the SARS-CoV-2 dissemination aligned with social distancing,isolation measures,and vaccination.Surveillance data from the city of Rio de Janeiro provided a case study to analyze possible scenarios,including non-pharmaceutical interventions and vaccination in the epidemic scenario.Our results demonstrate that the combination of vaccination and policies of transmission suppression potentially lowered the number of hospitalized cases by 380þand 66þthousand cases,respectively,compared to an absence of such policies.On top of transmission suppressiononly policies,vaccination impacted more than 230þthousand averted hospitalized cases and 43þthousand averted deaths.Therefore,health surveillance activities should be maintained along with vaccination planning in scheduled groups until a large vaccinated coverage is reached.Furthermore,this analytical framework enables evaluation of such scenarios. | Naiara C.M.Valiati Daniel A.M.Villela | 2022 | Infectious Disease Modelling2022，7，1： | 0 |
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