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| 1 | Argonaute:The executor of small RNA function显示文摘The discovery ot small non-coding RNAs- microRNA(miRNA),short interfering RNA(siRNA) and PIWIinteracting RNA(piRNA)- represents one of the most exciting frontiers in biology specifically on the mechanism of gene regulation.In order to execute their functions,these small RNAs require physical interactions with their protein partners,the Argonaute(AGO) family proteins.Over the years,numerous studies have made tremendous progress on understanding the roles of AGO in gene silencing in various organisms.In this review,we summarize recent progress of AGO-mediated gene silencing and other cellular processes in which AGO proteins have been implicated with a particular focus on progress made in flies,humans and other model organisms as compliment. | Azali Azlan Najat Dzaki Ghows Azzam | 2016 | Journal of Genetics and Genomics2016，43，8： | 10 |
| 2 | Transcranial magnetic stimulation for geriatric depression: Promises and pitfalls显示文摘As the global population gets older, depression in the elderly is emerging as an important health issue. A major challenge in treating geriatric depression is the lack of robust efficacy for many treatments that are of significant benefit to depressed working age adults. Repetitive transcranial magnetic stimulation(r TMS) is a novel physical treatment approach used mostly in working age adults with depression. Many TMS trials and clinics continue to exclude the elderly from treatment citing lack of evidence in this age group. In this review, we appraise the evidence regarding the safety and efficacy of rT MS in the elderly. A consistent observation supporting a high degree of tolerability and safety among the elderly patients emerged across the Randomised Controlled Trials and the uncontrolled trials. Further, there is no reliable evidence negating the utility of rT MS in the elderly with depression. We also identified several factors other than age that moderate the observed variations in the efficacy of rT MS in the elderly. These factors include but not limited to:(1) brain atrophy;(2) intensity and number of pulses(dose-response relationship); and(3) clinical profile of patients. On the basis of the current evidence, the practice of excluding elderly patients from TMS clinics and trials cannot be supported. | Priyadharshini Sabesan Sudheer Lankappa Najat Khalifa Vasudevan Krishnan Rahul Gandhi Lena Palaniyappan | 2015 | World Journal of Psychiatry2015，5，2： | 7 |
| 3 | Magnetic Resonance Elastography for the Noninvasive Staging of Liver Fibrosis显示文摘 | Laurent Huwart Christine Sempoux Eric Vicaut Najat Salameh Laurence Annet Etienne Danse Frank Peeters Leon C. ter Beek Jacques Rahier Ralph Sinkus Yves Horsmans Bernard E. Van Beers | 2008 | Gastroenterology2008，，1： | 4 |
| 4 | Study on the SEIQR model and applying the epidemiological rates of COVID-19 epidemic spread in Saudi Arabia显示文摘This article attempts to establish a mathematical epidemic model for the outbreak of the new COVID-19 coronavirus.A new consideration for evaluating and controlling the COVID-19 outbreak will be constructed based on the SEIQR Pandemic Model.In this paper,the real data of COVID-19 spread in Saudi Arabia has been used for the mathematical model and dynamic analyses.Including the new reproductive number and detailed stability analysis,the dynamics of the proposed SEIQR model have been applied.The local sensitivity of the reproduction number has been analyzed.The domain of solution and equilibrium based on the SEIQR model have been proved using a Jacobian linearization process.The state of equilibrium and its significance have been proved,and a study of the integrity of the disease-free equilibrium has been carried out.The Lyapunov stability theorem demonstrated the global stability of the current model equilibrium.The SEIQR model has been numerically validated and projected by contrasting the results from the SEIQR model with the actual COVID-19 spread data in Saudi Arabia.The result of this paper shows that the SEIQR model is a model that is effective in analyzing epidemic spread,such as COVID-19.At the end of the study,we have implemented the protocol which helped the Saudi population to stop the spread of COVID-19 rapidly. | Hamdy Youssef Najat Alghamdi Magdy A.Ezzat Alaa A.El-Bary Ahmed M.Shawky | 2021 | Infectious Disease Modelling2021，6，1： | 3 |
| 5 | Assessment of MRI and MRCP in diagnosis of biliary cystadenoma and cystadenocarcinoma显示文摘 | Ma?té Lewin Najat Mourra Isabelle Honigman Jean-Fran?ois Fléjou Rolland Parc Lionel Arrivé Jean-Michel Tubiana | 2006 | European Radiology2006，，2： | 2 |
| 6 | Anevaliation of distinct volu metrcand functional MIU contrbution stoward understanding age and task performance; A study in the basal ganglia显示文摘 | Scott A L Emily M B Najat M H et sl | 2007 | Brain research2007，11，35： | 1 |
| 7 | FDG positron emission tomography/computed tomography studies of Wilms’ tumor显示文摘 | A. K. M. Moinul Hossain Barry L. Shulkin Michael J. Gelfand Humayun Bashir Najat C. Daw Susan E. Sharp Helen R. Nadel Jeffrey S. Dome | 2010 | European Journal of Nuclear Medicine and Molecular Imaging2010，，7： | 1 |
| 8 | The use of vaterite as a trap for metallic ions in water study of eopper/vaterite and manganese/ vaterite systems显示文摘 | SAMER A ELIAS S NAJAT N A | 2009 | Leha1:ese Science ]ournal2009，10，2： | 1 |
| 9 | Seasonal, diurnal and nocturnal behaviors of lower carbonyl compounds in the urban environment of Beirut, Lebanon显示文摘 | Samar G. Moussa Mutassem El-Fadel Najat A. Saliba | 2006 | Atmospheric Environment2006，，14： | 1 |
| 10 | Characterization of KATP-channels in rat basilar and middle cerebral arteries:Studies of vasomotor responses and mRNA expression 显示文摘 | Inger J O Camilla H M Najat El-Barlaki | 2005 | Eur J Pharmacol2005，523，13： | 1 |
| 11 | The elemental analysis of staple foods for children in Tanzania as a step to the improvement of their nutrition and health显示文摘 | Najat K Mohammed Nicholas M Spyrou | 2009 | Applied Radiation and Isotopes2009，67，： | 1 |
| 12 | Modeling uncertainty in stability analysis for design of embankment dams on diffi- cult foundations显示文摘 | A zm S Al-Homoud Najat Tanash | 2004 | Engineering Geology2004，，71： | 1 |
| 13 | Implication of MYH in Colorectal Polyposis显示文摘 | Jérémie H. Lefevre Christelle M. Rodrigue Najat Mourra Malika Bennis Jean-Fran?ois Flejou Rolland Parc Emmanuel Tiret Christian Gespach Yann R. Parc | 2006 | Annals of Surgery2006，，6： | 1 |
| 14 | The effect of gamma irradiation dose on cucumber (Cucumis sativus L.) haploid embryo production显示文摘 | Najat Mustafa Faris Vesselina Nikolova Katarzyna Niemirowicz-Szczytt | 1999 | Acta Physiologiae Plantarum1999，，4： | 1 |
| 15 | What made sesquiterpene lactones reach cancer clinical trials?显示文摘 | Akram Ghantous Hala Gali-Muhtasib Heikki Vuorela Najat A. Saliba Nadine Darwiche | 2010 | Drug Discovery Today2010，，15： | 1 |
| 16 | Metastatic osteosarcoma显示文摘 | Najat C.Daw Catherine A.Billups CarlosRodriguez‐Galindo M. BethMcCarville Bhaskar N.Rao Alvida M.Cain Jesse J.Jenkins Michael D.Neel William H.Meyer | 2006 | Cancer2006，，2： | 1 |
| 17 | Metastatic osteosarcoma显示文摘 | Najat C.Daw Catherine A.Billups CarlosRodriguez‐Galindo M. BethMcCarville Bhaskar N.Rao Alvida M.Cain Jesse J.Jenkins Michael D.Neel William H.Meyer | 2006 | Cancer2006，，2： | 1 |
| 18 | Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors显示文摘 | Carlos Rodriguez-Galindo Kristine R. Crews Clinton F. Stewart Wayne Furman J. Carl Panetta Najat C. Daw Alvida Cain Ming Tan Peter H. Houghton Victor M. Santana | 2006 | Cancer Chemotherapy and Pharmacology2006，，1： | 1 |
| 19 | Distribution and location of polycyctic aromatic hydrocarbons(PAHs)and PAH-degrading bacteria within polluted soil aggregates显示文摘 | Jean-M Portal Timothy Vogel | 2001 | Biodegration2001，12，： | 1 |
| 20 | Modelling rainfall-discharge at a mean inter-yearly scale in northern Algeria显示文摘 | MUSTAPHA T JEAN P L NAJAT B | 2004 | Journal of Hydrology2004，296，14： | 1 |
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