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| 1 | A review on therapeutic potential of Nigella sativa:A miracle herb显示文摘Nigella sativa(N.sativa)(Family Ranunculaceae)is a widely used medicinal plant throughout the world.It is very popular in various traditional systems of medicine like Unani and Tibb,Ayurveda and Siddha.Seeds and oil have a long history of folklore usage in various systems of medicines and food.The seeds of N.saliva have been widely used in the treatment of different diseases and ailments.In Islamic literature,it is considered as one of the greatest forms of healing medicine.It has been recommended for using on regular basis in Tibb-e-Nabwi(Prophetic Medicine).It has been widely used as antihypertensive,liver tonics,diuretics,digestive,anti-diarrheal,appetite stimulant,analgesics,anti-bacterial and in skin disorders.Extensive studies on N.sativa have been carried out by various researchers and a wide spectrum of its pharmacological actions have been explored which may include antidiabetic,anticancer,immunomodulator,analgesic,antimicrobial,anti-inflammatory,spasmolytic,bronchodilator,hepato-protective,renal protective,gaslro-prolective,antioxidant properties,etc.Due to its miraculous power of healing,N.sativa has got the place among the top ranked evidence based herbal medicines.This is also revealed that most of the therapeutic,properties of this plant are due to the presence of thymoquinone which is major bioactive component of the essential oil.The present review is an effort to provide a detailed survey of the literature on scientific researches of pharmacognostical characteristics,chemical composition and pharmacological activities of the seeds of this plant. | Aftab Ahmad Asif Husain Mohd Mujeeb Shah Alam Khan Abul Kalam Najmi Nasir Ali Siddique Zoheir A.Damanhouri Firoz Anwar | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，5： | 16 |
| 2 | 不同流场下进气对质子交换膜燃料电池性能的影响显示文摘流场的结构对于质子交换膜燃料电池(PEMFC)的水管理和气体的传递具有十分重要的影响,相关研究一直是燃料电池的研究热点与重点。本文以纯氧气和空气作为阴极氧化剂,通过电池的性能测试、极化曲线和电化学阻抗分析等原位实验,分析了气体的流动与传输、不同流场下的电流密度、入口反应气体浓度等条件对电池性能的影响。实验结果表明,提高氧气浓度可以获得更好的质子交换膜燃料电池性能和最小化活化损失,纯氧气、波状流场的使用效果随进气量的变化而有明显的变化。 | Aezid-Ul-Hassan Najmi 刘智 杜青 焦魁 | 2021 | 工程热物理学报2021，42，2： | 4 |
| 3 | The correlation between keratoconus and eye rubbing: a review显示文摘Keratoconus is a non-inflammatory disorder which is gradual in development;corneal thinning and ectatic protrusion characterizes it. Keratoconus prevalence varies between different regions depending on several factors that affecting its prevalence. There are risk factors for developing keratoconus such as demographic and environmental factors. It was suggested that eye rubbing was associated with the development of keratoconus. The main aim of this review was to summarize the literature data about keratoconus and to identify the role of eyerubbing in the aetiology of the disease. A number of 24 articles was reviewed through the Pub Med, Google Scholar and Research Gates. There are many keywords used such as keratoconus, aetiology of keratoconus, eye rubbing, keratoconus prevalence, keratoconus and eye rubbing correlation. We concluded that eye rubbing causes the thinning of keratocyte, and the degree of effect of eye rubbing depends on the period and force of performing eye rubbing. It is recommended to avoid eye rubbing to prevent keratoconus, this can be achieved by avoiding itching and treating dryness of the eye and avoiding wearing eye lenses. | Hatim Najmi Yara Mobarki Khalid Mania Bashaer Altowairqi Mohammed Basehi Mohammed Salih Mahfouz Mona Elmahdy | 2019 | International Journal of Ophthalmology(English edition)2019，12，11： | 4 |
| 4 | Nigella sativa protects against isoproterenol-induced myocardial infarction by alleviating oxidative stress,biochemical alterations and histological damage显示文摘Objective: To evaluate the cardioprotective effect of Nigella sativa L.(N.sativa) in isoproterenol-induced myocardial infarction(MI).Methods: Groups were treated with different doses of ethanol extract of N.sativa(EENS)and N.sativa oil alone and along with enalapril for 28 days.MI was induced by subcutaneous administration of isoproterenol(85 mg/kg) in two consecutive doses.Levels of cardiac biomarkers and antioxidant enzymes such as creatine kinase–N-acetyl-L-cysteine, lactate dehydrogenase, aspartate aminotransferase, malondialdehyde, superoxide dismutase, reduced glutathione and catalase were evaluated along with gross histopathological examination.Results: Isoproterenol(85 mg/kg) induced MI by causing the significant(P < 0.01)reduction in the activity of cardiac biomarkers(creatine kinase–N-acetyl-L-cysteine,lactate dehydrogenase, aspartate aminotransferase) and antioxidant markers(superoxide dismutase, catalase, glutathione) along with significant(P < 0.01) increase in the level of malondialdehyde.Furthermore, histopathological evaluation also confirmed the isoproterenol-induced MI.Pretreatment with EENS(800 mg/kg) and combination of EENS(800 mg/kg) with enalapril(1 mg/kg) significantly(P < 0.01) prevented the development of these alteration and restored activity of cardiac biomarkers as well as antioxidant markers almost near to normal levels.Histopathological evaluation of cardiac tissue further confirmed the restoration of biochemical activity.Conclusions: Experimental findings thus indicate that EENS(800 mg/kg) demonstrated cardioprotective effect against isoproterenol-induced MI by restoring cardiac biomarkers and antioxidant status. | Md.Quamrul Hassan Mohd.Akhtar Sayeed Ahmed Aftab Ahmad Abul Kalam Najmi | 2017 | Asian Pacific Journal of Tropical Biomedicine2017，7，4： | 4 |
| 5 | 准分子激光治疗性角膜切削术在复发性角膜糜烂中的应用(英文)显示文摘目的:评价早期实施准分子激光治疗性角膜切削术(PTK)对复发性角膜糜烂(RCE)的临床治疗效果。方法:筛选经常规治疗方法无效,但未经基质穿刺及角膜接触镜治疗的RCE临床连续病例23例(25眼),平均病程为9.3mo(2mo~3a),经全面眼科检查后行PTK治疗,切削深度为10μm,光学区为4~8mm。对比PTK手术前后裸眼视力(UCVA)、最佳矫正视力(BCVA)、等效球镜(SE)以及散光度数(RC)。结果:术后平均随访10.1±5.5mo(4.2~19.2mo),免于复发率为96%,平均BCVA显著提高(术前为0.69±0.30,术后为0.90±0.23,P<0.001),平均SE变化不明显(术前0.41±1.67DS,术后0.35±1.63DS,P=0.26),但平均RC显著降低(术前-1.22±0.90DC,术后-0.57±0.57DC,P<0.001)。结论:对于早期RCE患者,PTK是一种安全有效的治疗方法,它可使绝大多数患者的角膜上皮快速愈合而迅速减轻症状,并可显著提高最佳矫正视力。 | M N Hashemian S Moghimi F Rahimi B Dehsarvi Z Najmi M T Rajabi | 2007 | 国际眼科杂志2007，7，6： | 2 |
| 6 | Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence suscepti- bility and severity of puhnonary tuberculosis in the Asian Indian population 显示文摘 | Najmi N Kaur G Sharma S K | 2010 | Tissue Antigens2010，76，2： | 1 |
| 7 | Evaluation of compliance and outco-mes of a management protocol for massive postpartum hemorrhage at a tertiary care hospital in Pakistan显示文摘 | Sheikh L Najmi N Khalid U | 2011 | BMC Pregnancy Childbirth2011，11，： | 1 |
| 8 | Imae classification by a two-dimensional hidden Markov model显示文摘 | Najmi Amir Gray Robert M | 2000 | IEEE Trans Signal Processing2000，48，： | 1 |
| 9 | Evaluationof compliance and outcomes of a management protocol for massive postpartum hemorrhage at a tertiarycare hospital in Pakistan显示文摘 | Lumaan Sheikh Nida Najmi Umair Khalid | 2011 | BM C Pregnancy Childbirth2011，，11： | 1 |
| 10 | Image classification by a two-dimensional hidden Markov model显示文摘 | Li J Najmi A Gray R M | 2000 | IEEE Transactions on Signal Processing2000，48，2： | 1 |
| 11 | Pharmacological basis for use of Pistacia integerrima leaves in hyperuricemia and gout显示文摘 | Ahamd NS Farmn M Najmi MH | | 0，，03： | 1 |
| 12 | Effect of l-ornithine laspartate against thioacetamide-induced hepatic damage in rats显示文摘 | Najmi A Pillai K Pal S | 2010 | Indian J Pharmacol2010，42，6： | 1 |
| 13 | Design of round reinforced-concrete columns 显示文摘 | Tayem A Najmi A | 1996 | Engineering Structures1996，122，9： | 1 |
| 14 | Effect of sarcosine(a glycine transport 1 inhibitor)and risperidone(an atypical antipsychotic drug)on mk-801 induced learning and memory deficits in rats显示文摘 | KUMAR V AHMAD M A NAJMI A K | 2016 | Drug Res(Stuttg)2016，66，1： | 1 |
| 15 | Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population显示文摘 | Najmi N Kaur G Sharma SK | 2010 | Tissue Antigens2010，76，2： | 1 |
| 16 | AttentionalBiastowardSuicide-RelatedStimuliPredictsSuicidalBehavior显示文摘 | ChaCB NajmiS ParkJM etal | 2010 | Abnorm Psychol2010，119，3： | 1 |
| 17 | A comprehensive review of solid particle erosion model- ing for oil and gas wells and pipelines applications 显示文摘 | PARIS M NAJMI K NAJAFIFARD F | 2014 | Journal of Natural Gas Science and Engineer- ing2014，21，： | 1 |
| 18 | Hemiparkinson-ism-hemiatrophy syndrome显示文摘 | AYROMLOU H NAJMI S ARAMI MA | 2011 | Archives of Iranian Medicine2011，14，： | 1 |
| 19 | Image classification by a two-dimensional hidden Markov model显示文摘 | Li J Najmi A Gray R M | 2000 | IEEE Transactions on Signal Processing2000，48，2： | 1 |
| 20 | Secondary Artisan-Verysise intraocular lens implantation for aphakic correction in post- traumatic vitrectomized eye 显示文摘 | Riazi M Moghimi S Najmi Z | 2008 | Eye2008，22，： | 1 |
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