|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A novel chemotherapy strategy for advanced hepatocellular carcinoma: a multicenter retrospective study显示文摘Background:Chemotherapy is a common treatment for advanced hepatocellular carcinoma,but the effect is not satisfactory.The study aimed to retrospectively evaluate the effects of adding all-trans-retinoic acid(ATRA)to infusional fluorouracil,leucovorin,and oxaliplatin(FOLFOX4)for advanced hepatocellular carcinoma(HCC).Methods:We extracted the data of patients with advanced HCC who underwent systemic chemotherapy using FOLFOX4 or ATRA plus FOLFOX4 at the Eastern Hepatobiliary Surgery Hospital,First Hospital of Jilin University,and Zhejiang Sian International Hospital and retrospectively compared for overall survival.The Cox proportional hazards model was used to calculate the hazard ratios for overall survival and disease progression after controlling for age,sex,and disease stage.Results:From July 2013 to July 2018,111 patients with HCC were included in this study.The median survival duration was 14.8 months in the ATRA plus FOLFOX4 group and 8.2 months in the FOLFOX4 only group(P<0.001).The ATRA plus FOLFOX4 group had a significantly longer median time to progression compared with the FOLFOX4 group(3.6 monthsvs.1.8 months,P<0.001).Hazard ratios for overall survival and disease progression were 0.465(95%confidence interval:0.298–0.726;P=0.001)and 0.474(0.314–0.717;P<0.001)after adjusting for potential confounders,respectively.Conclusion:ATRA plus FOLFOX4 significantly improves the overall survival and time to disease progression in patients with advanced HCC. | Juxian Sun Chang Liu Jie Shi Nanya Wang Dafeng Jiang Feifei Mao Jingwen Gu Liping Zhou Li Shen Wan Yee Lau Shuqun Cheng | 2022 | Chinese Medical Journal2022，135，19： | 2 |
| 2 | Phthalate esters detected in various water samples and biodegradation of the phthalates by microbes isolated from river water 显示文摘 | HASHIZUME K NANYA J TODA C YASUI T NAGANO H KOJIMA N | 2002 | Biological and Pharmaceutical Bulletin2002，25，2： | 1 |
| 3 | Analysis and optimization of temperature distribution in carbon fiber reinforced composite materials during microwave curing process显示文摘 | Nanya Li Yingguang Li Xiang Hang James Gao | 2014 | Journal of Materials Processing Tech2014，，3： | 1 |
| 4 | Tooling design and microwave curing technologies for the manufacturing of fiber-reinforced polymer composites in aerospace applications显示文摘 | Yingguang Li Nanya Li James Gao | 2014 | 2014 (1-4)2014，，1： | 1 |
| 5 | A hierachical adaptive distributed system-level diagnosis algorithm显示文摘 | Duarte E Nanya T | 1998 | IEEE Transactions on Computers1998，47，1： | 1 |
| 6 | A hierachical adaptive distributed systemlevel diagnosis algorithm显示文摘 | Nanya T | 1998 | IEEE Transactions on Computers1998，47，1： | 1 |
| 7 | Combination of radiofrequency ablation and sequential cellular immunotherapy improves progression‐free survival for patients with hepatocellular carcinoma显示文摘 | Jiuwei Cui Nanya Wang Hengjun Zhao Haofan Jin Guanjun Wang Chao Niu Hiroshi Terunuma Hua He Wei Li | 2014 | Int. J. Cancer2014，，： | 1 |
| 8 | Inhibitory effects of a novel arometase inhibitor,YM511,on growth of endometrial expant and insulin-like growth factor-1 gene expression in rats with experimental endometrinsis显示文摘 | Kudoh M Susaki Y Nanya T | 1997 | J Steroid Biochem Mol Biol1997，63，13： | 1 |
| 9 | A hierarchical adaptive distributed system-level diagnosis algorithm 显示文摘 | Elias procopio Duarte Jr Takashi Nanya | 1998 | IEEE Trans1998，47，1： | 1 |
| 10 | A hierarchical adaptive distributed system-level diagnosis algorithm显示文摘 | NANYA T | 1998 | IEEE Transactions on Computers1998，47，1： | 1 |
| 11 | Phthalate esters detected in various water samples and biodegradation of the phthalates by microbes isolated from river water显示文摘 | HASHIZUME K NANYA J TODA C | 2002 | Biol Pharm Bull2002，25，2： | 1 |
| 12 | A hierarchical adaptive distributed system-level diagnosis algorithm显示文摘 | Elias procopio Duarte Jr Takashi Nanya | 1998 | IEEE Trans1998，47，1： | 1 |
| 13 | A hierarchical adaptive distributed system-level diagnosis algorithm显示文摘 | Duarte E Nanya T | 1998 | IEKK Transactions on Computers1998，47，1： | 1 |
| 14 | A hierarchical adaptive distributed system-level diagnosis algorithm显示文摘 | DUARTE E NANYA T | 1998 | IEEE Trans on Computers1998，47，1： | 1 |
| 15 | Seizure frequency and obstetric complications at advanced maternal age:a preliminary observational study in women with epilepsy显示文摘Background:Seizure control during pregnancy and obstetric outcomes are of important concerns for women with epilepsy(WWE)and their families.Advanced maternal age(≥35 years)shows a growing trend in the society with changes of lifestyle,which also occurs in diseased populations.The advanced maternal age is an independent factor for some unsatisfying obstetric outcomes.In this study we explored the seizure control and obstetric complications associated with advanced maternal age in WWE.Methods:This study was based on the epilepsy pregnancy registry at West China Hospital.Patients with epilepsy in this registry who were aged 35 or older when starting pregnancy were included in this study.Their basic demographics and detailed information on epilepsy management and obstetric issues in all trimesters and during 1-year follow-up after birth were documented and reviewed.Data were processed by IBM SPSS version 22.0.The demographic characteristics,seizure frequency,treatment change,obstetric complications,and outcomes were analyzed and compared.Results:Fifteen patients were included in this study,with an average age of 36.32±2.39 years at pregnancy,and 73.33%of them were primiparas.The change of seizure frequency during pregnancy was not in a clear pattern,but there was an increased incidence of tonic-clonic seizures during the mid-and last trimesters.More than 20%of the patients had obstetric complications throughout the trimesters,including vaginal bleeding,hypothyroidism,and pre-eclampsia.The pre-eclampsia seemed extraordinarily complicated with other conditions.However,none of the complications were related with malformations or poor outcome of babies after 1-year follow-up.Conclusion:Advanced maternal age combined with WWE is associated with frequent common obstetric complications.Future controlled studies with large sample sizes are needed to explore the related risks in comparison with other WWE and non-epileptic populations. | Hui Gao Nanya Hao Shanrui Liu Dong Zhou | 2021 | Acta Epileptologica2021，3，1： | 0 |
| 16 | Disease awareness and dietary habits of patients with epilepsy in western China:a cross-sectional study显示文摘Background:The optimal management of epilepsy includes engaging patients through education on knowledge of the disease,its treatment and diet control.Methods:This was a cross-sectional survey-based cohort study,aimed to investigate the awareness of epilepsy in Chinese patients and to understand their dietary habits.Participants were consecutively enrolled from epileptic patients treated in a single epilepsy center from October 1,2019 to February 29,2020.A self-reported questionnaire(Cronbach’sα=0.758)consisting of 3 parts was sent to 407 patients with epilepsy.The questionnaire included items on demographic information,epilepsy features,awareness of epilepsy treatment and dietary habits.Results:About half of the patients(53.8%,219/407)thought epilepsy was curable and only 80%knew that the first choice of treatment is medication.While 58.6%of the patients with low educational level preferred the use of antiepileptic drugs(p=0.014),52.7%believed that the medication should not be stopped immediately after seizure control(p=0.026),especially after surgery(40.5%,p=0.011).Patients with lower household monthly incomes had less awareness of the use of antiepileptic drugs than patients with higher incomes:only 39.2 and 49.8%of patients with lower incomes thought that the drugs could be stopped after epilepsy surgery or seizure control,respectively,compared to 51.6 and 66.1%with higher incomes.Alcohol(86.2%),caffeine(56.8%)and strong tea(49.1%)were top three foods considered by the patients to be avoided to prevent seizures.Approximately 30.2%of patients identified at least one food that made them susceptible to seizures.Conclusions:Patient education on epilepsy,antiepileptic drugs and diet for management of seizures should be provided especially to patients with less education,lower income or inaccurate beliefs of epilepsy in Western China. | Qi Zhang Wenjing Li Enzhi Li Xiao Yang Nanya Hao Bo Yan Dong Zhou Xiaoting Hao | 2021 | Acta Epileptologica2021，3，1： | 0 |
| 17 | A compensation approach to the tool used in autoclave based on FEA显示文摘Optimization of the curing process can not control the deformation of composite part prepared in autoclave accurately.And traditional 'trial-and-error' tool surface compensation approach is low efficiency,high cost and can not control part deformation quantificationally.In order to address these issues,tool compensation approach based on FEA is presented.Model of multi-field coupling relationship in autoclave is realized.And finite element analysis model of composite part's curing process is developed to analyze part deformation.According to displacement of the part surface nodes after deformation,tool surface which compensated by the displacement of composite part which analyzed by FEA is used to control part deformation.A cylindrical composite part is analyzed to verify the approach,and the result proves the correctness and validity of the approach. | Zhang Ji Li Yingguang Li Nanya Liao Wenhe | 2012 | Computer Aided Drafting,Design and Manufacturing2012，22，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员