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| 1 | Systematic review and meta-analysis of colon cleansing preparations in patients with inflammatory bowel disease显示文摘AIM To performed a systematic review and meta-analysis to determine any possible differences in terms of effectiveness, safety and tolerability between existing colon-cleansing products in patients with inflammatory bowel disease.METHODS Systematic searches were performed( January 1980-September 2016) using MEDLINE, EMBASE, Scopus, CENTRAL and ISI Web of knowledge for randomized trials assessing preparations with or without adjuvants, given in split and non-split dosing, and in high(> 3 L) or low-volume(2 L or less) regimens. Bowel cleansing quality was the primary outcome. Secondary outcomes included patient willingness-torepeat the procedure and side effects/complications.RESULTS Out of 439 citations, 4 trials fulfilled our inclusion criteria(n = 449 patients). One trial assessed the impact of adding simethicone to polyethylene glycol(PEG) 4 L with no effect on bowel cleansing quality, but a better tolerance. Another trial compared senna to castor oil, again without any differences in term of bowel cleansing. Two trials compared the efficacy of PEG high-volume vs PEG low-volume associated to an adjuvant in split-dose regimens: PEG low-dose efficacy was not different to PEG high-dose; OR = 0.84(0.37-1.92). A higher proportion of patients were willing to repeat low-volume preparations vs high-volume; OR = 5.11(1.31-20.0). CONCLUSION In inflammatory bowel disease population, PEG lowvolume regimen seems not inferior to PEG high-volume to clean the colon, and yields improved willingness-torepeat. Further additional research is urgently required to compare contemporary products in this population. | Sophie Restellini Omar Kherad Talat Bessissow Charles Ménard Myriam Martel Maryam Taheri Tanjani Peter L Lakatos Alan N Barkun | 2017 | World Journal of Gastroenterology2017，23，32： | 16 |
| 2 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 3 | Effects of aerobic physical exercise in the elderly with type 2 diabetes mellitus显示文摘 | Tessier D Ménard J Fülp T | 2000 | Archives of gerontology and geriatrics2000，31，2： | 1 |
| 4 | A web service for controlling the quality of measurements of global solar irradiation显示文摘 | Geger M Diabaté L Ménard L | | 0，，06： | 1 |
| 5 | Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma显示文摘 | Rousseau B Me nard L Haurie V | 2007 | Hepatology2007，46，4： | 1 |
| 6 | The E2 ubiquitin-conjugating enzymes, AtUBC1 and AtUBC2, play redundant roles and are involved in activation of FLC expression and repression offlowering in Arabidopsis thaliana显示文摘 | Xu L M~nard R Berr A | 2009 | The Plant Journal2009，57，： | 1 |
| 7 | From iatrogenic digestive perforation to complete anastomotic disunion:endoscopic stenting as a new concept of'stent-guided regeneration and re-epithelialization'显示文摘 | Amrani L Ménard C Berdah S | 2009 | Gastrointest Endosc2009，69，7： | 1 |
| 8 | Plant genome size estimation by flow cytometry: inter-laboratory comparison显示文摘 | Dolezel J Greilhuber J Lucretti S Meister A Lysak MA Nard L Obermayer R | 1998 | Ann Bot1998，82，： | 1 |
| 9 | A hierarchical controller for miniature VTOL UAVs: Design and stability analysis using singular perturbation theory显示文摘 | Sylvain Bertrand Nicolas Guénard Tarek Hamel Hélène Piet-Lahanier Laurent Eck | 2011 | Control Engineering Practice2011，，10： | 1 |
| 10 | Comparison of dorsal and ventral spinal root regeneration through semipermeable guidance channels显示文摘 | McCormack M L Goddard M Guénard V Aebischer P | 1991 | J Comp Neurol1991，313，： | 1 |
| 11 | Role of p53 in HER2-induced Proliferation or Apoptosis显示文摘 | Casalini P Botta L Ménard S | 2001 | J Biol Chem2001，276，12： | 1 |
| 12 | 5′-to-3′ exonribonuclease activity in bacteria:Role of RNase J1 in rRNA maturation and 5′ stability of mRNA显示文摘 | Mathy N Be'nard L Pellegrini O | 2007 | Cell2007，129，4： | 1 |
| 13 | Hydrogen discharge on a Raney nickel composite-coated electrode显示文摘 | Choquette Y Ménard H Brossard L | 1989 | International Journal of Hydrogen Energy1989，14，： | 1 |
| 14 | Electrocatalyticperformance of composite-coated electrodes for alka-line water electrolysis显示文摘 | Choquette Y Ménard H Brossard L | 1990 | International Journal of Hy-drogen Energy1990，15，1： | 1 |
| 15 | Electrocatalytic performance of composite-coated electrodes for alkaline water electrolysis显示文摘 | Choquette Y Ménard H Brossard L | 1990 | International Journal of Hydrogen Energy1990，15，： | 1 |
| 16 | Hydrogen dis-charge on a raney nickel composite-coated electrode显示文摘 | Choquette Y Ménard H Brossard L | 1989 | International Journal of Hydrogen Energy1989，14，9： | 1 |
| 17 | Pontin and reptin,two related AT-Pases with multiple roles in cancer显示文摘 | Huber O Ménard L Haurie V | | 0，，17： | 1 |
| 18 | Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin throμgh a new posttranslational mechanism显示文摘 | Haurie V Ménard L Nicou A | 2009 | Hepatology2009，50，6： | 1 |
| 19 | Synthesis and Biological Evaluation of D-Ring-Modified Taxanes:5(20)-Azadocetaxel Analogs显示文摘 | Marder-Karsenti R Dubois J Bricard L Guénard D Guéritte-Voegelein F | 1997 | Journal of Organic Chemistry1997，62，19： | 1 |
| 20 | Expression,purification,and biochemical characterization of enteroaggregative Escherichia coli heat-stable enterotoxin 1显示文摘 | Ménard L P | | 0，，02： | 1 |
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