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| 1 | Influence of proton pump inhibitors on gastritis diagnosis and pathologic gastric changes显示文摘AIM: To investigate the influence of proton pump inhibitors(PPIs) exposure on the diagnosis of Helicobacter pylori(H. pylori) gastritis and intestinal metaplasia.METHODS: Chronic PPI use is associated with masking of H. pylori infection. Patients with H. pylori infection are predisposed to gastric and duodenal ulcers, and long-term infection with this organism has been associated with gastric mucosal atrophy and serious long-term complications, such as gastric lymphoma and adenocarcinoma. Three hundred patients diagnosed with gastritis between January 2008 and April 2010 were included in our study. The computerized medical database of these patients was reviewed retrospectively in order to assess whether the type of gastritis diagnosed(H. pylori vs non-H. pylori gastritis) is influenced by PPI exposure. H. pylori density was graded as low, if corresponding to mild density following the Updated Sydney System, or high, if corresponding to moderate or severe densities in the Updated Sydney System.RESULTS: Patients were equally distributed between males and females with a median age at the time of diagnosis of 50 years old(range: 20-87). The histological types of gastritis were classified as H. pylori gastritis(n = 156, 52%) and non-H. pylori gastritis(n = 144, 48%). All patients with non-H. pylori gastritis had inactive chronic gastritis. Patients with no previous PPI exposure were more likely to be diagnosed with H. pylori gastritis than those with previous PPI exposure(71% vs 34.2%, P < 0.001). Intestinal metaplasiawas more likely to be detected in the latter patients(1.4% vs 6.5%, P = 0.023). Multivariate analysis has also demonstrated that in the presence of previous PPI exposure(OR = 0.217, 95%CI: 0.123-0.385), GERD(OR = 0.317, 95%CI: 0.132-0.763, P = 0.01), alcohol intake(OR = 0.396, 95%CI: 0.195-0.804, P = 0.01), the detection of H. pylori was less likely. Chronic use of PPIs may mask H. pylori infections promoting the diagnosis of non-H. pylori gastritis and leads to a significant drop in H. pylori densities and to an increased risk of intestinal metaplasia.CONCLUSION: The use of PPIs masks H. pylori infection, promotes the diagnosis of non-H. pylori inactive chronic gastritis diagnosis, and increases the incidence of intestinal metaplasia. | Soumana C Nasser Mahmoud Slim Jeanette G Nassif Selim M Nasser | 2015 | World Journal of Gastroenterology2015，21，15： | 7 |
| 2 | Investigation of soliton solutions with different wave structures to the(2+1)-dimensional Heisenberg ferromagnetic spin chain equation显示文摘The principal objective of this article is to construct new and further exact soliton solutions of the(2+1)-dimensional Heisenberg ferromagnetic spin chain equation which investigates the nonlinear dynamics of magnets and explains their ordering in ferromagnetic materials.These solutions are exerted via the new extended FAN sub-equation method.We successfully obtain dark,bright,combined bright-dark,combined dark-singular,periodic,periodic singular,and elliptic wave solutions to this equation which are interesting classes of nonlinear excitation presenting spin dynamics in classical and semi-classical continuum Heisenberg systems.3D figures are illustrated under an appropriate selection of parameters.The applied technique is suitable to be used in gaining the exact solutions of most nonlinear partial/fractional differential equations which appear in complex phenomena. | M S Osman K U Tariq Ahmet Bekir A Elmoasry Nasser S Elazab M Younis Mahmoud Abdel-Aty | 2020 | Communications in Theoretical Physics2020，72，3： | 4 |
| 3 | A modular clutter rejection technique for FLIR imagery using region-based principal component analysis显示文摘 | Syed A Rizvi Nasser M Nasrabadi | 2002 | Pattern Recognition2002，35，： | 2 |
| 4 | Imaging response predictors following drug eluting beads chemoembolization in the neoadjuvant liver transplant treatment of hepatocellular carcinoma显示文摘BACKGROUND Drug-eluting bead transarterial chemoembolization(DEB-TACE)is an endovascular treatment to release chemotherapeutic agents within a target lesion,minimizing systemic exposure and adverse effects to chemotherapeutics.Therefore,identifying which patient characteristics may predict imaging response to DEB-TACE can improve treatment results while selecting the best candidates.Predictors of the response after DEB-TACE still have not been fully elucidated.This is the first prospective study performed with standardized DEBTACE technique that aim to identify predictors of radiological response,assessing patients clinical and laboratory characteristics,diagnostic imaging and intraprocedure data of the hepatocellular carcinoma treated in the neoadjuvant context for liver transplantation.AIM To identify pre-and intraoperative clinical and imaging predictors of the radiological response of drug-eluting bead transarterial chemoembolization(DEB-TACE)for the neoadjuvant treatment of hepatocellular carcinoma(HCC).METHODS This is prospective,cohort study,performed in a single transplant center,from 2011 to 2014.Consecutive patients with HCC considered for liver transplant who underwent DEB-TACE in the first session for downstaging or bridging purposes were recruited.Pre and post-chemoembolization imaging studies were performed by computed tomography or magnetic resonance.The radiological response of each individual HCC was evaluated by objective response using mRECIST and the percentage of necrosis.RESULTS Two hundred patients with 380 HCCs were examined.Analysis of the objective response(nodule-based analysis)demonstrated that HCC with pseudocapsules had a 2.01 times greater chance of being responders than those without pseudocapsules(P=0.01),and the addition of every 1mg of chemoembolic agent increased the chance of therapeutic response in 4%(P<0.001).Analysis of the percentage of necrosis through multiple linear regression revealed that the addition of each 1mg of the chemoembolic agent caused an average increase of 0.65%(P<0.001)in necrosis in the treated lesion,whereas the hepatocellular carcinoma with pseudocapsules presented 18.27%(P<0.001)increased necrosis compared to those without pseudocapsules.CONCLUSION The presence of a pseudocapsule and the addition of the amount of chemoembolic agent increases the chance of an objective response in hepatocellular carcinoma and increases the percentage of tumor necrosis following drug-eluting bead chemoembolization in the neoadjuvant treatment,prior to liver transplantation. | Francisco Leonardo Galastri Felipe Nasser Breno Boueri Affonso Leonardo Guedes Moreira Valle Bruno Calazans Odísio Joaquim Mauricio Motta-Leal Filho Paolo Rogério Salvalaggio Rodrigo Gobbo Garcia Márcio Dias de Almeida Ronaldo Hueb Baroni Nelson Wolosker | 2020 | World Journal of Hepatology2020，12，1： | 2 |
| 5 | Scopulariopsis endocardi- tis associated with Duran ring valvuloplasty 显示文摘 | Gentry LO Nasser MM Kielhofner M | 1995 | Tex Heart Inst J1995，22，1： | 1 |
| 6 | Dielectric and X-ray diffraction studies of barium titanate doped with ytterbium显示文摘 | MOLOKHIA N M ISSA M A A NASSER S A | 1984 | J Am Ceram Soc1984，67，2： | 1 |
| 7 | Evaluation of the in-vitro pediculicidal action of four known insecticides and three medicinal plant extracts 显示文摘 | MORSY T A EL-ELA R G NASSER M M | 2000 | J Egypt Soc Parasitol2000，30，3： | 1 |
| 8 | Design considerations and topology selection for 120 kW IGBT converter for EV fast charging显示文摘 | Nasser H Kutkut Deepak M Divan Donald W Novotny | 1998 | IEEE Transactions on Power Electronics1998，13，1： | 1 |
| 9 | Efficacy of Car- ditethus exiguus Poppius (Hemiptera: Anthocori- dae), as a predator of the coconut caterpillar, Opisina arenosella Walker (Lepidoptera: Xyloric- tidae) 显示文摘 | Nasser M Abdurahiman U C | 1998 | Journal of Entomological Research1998，22，4： | 1 |
| 10 | Identification of oligomers in polyethyleneterephthalate bottles for mineral water and fruit juice development and validation of a high-performance liquid chromatographic method for the determination of first series cyclic trimer显示文摘 | NASSER A L M LOPES L M X EBERLIN M N | 2005 | Journal of Chromatography A2005，1097，12： | 1 |
| 11 | Effect of electric current pulses on the recrystallization of copper 显示文摘 | Conrad H NASSER K SARDARI M | 1983 | Scripta metallurgica1983，17，3： | 1 |
| 12 | Dynamic Strain Measurements by Fiber Bragg Grating Sensor显示文摘 | Cusano A Cutolo A Nasser J Giordano M Calabro A | 2004 | Sensors and Actuators2004，110，： | 1 |
| 13 | Extended treatment duration for hepatitis C virus type 1:comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin显示文摘 | BERG T VON WAGNER M NASSER S | 2006 | Gastroenterology2006，130，： | 1 |
| 14 | Cloning, expression, and characterization of an alternatively spliced variant of human heparanase显示文摘 | Nasser NJ Avivi A Shushy M | 2007 | Biochem Biophys Bes Commun2007，354，1： | 1 |
| 15 | Numerical prediction of optimum hollowness and materical of hollow roller under combined loading 显示文摘 | Wisam M Vbu J Nasser M J | 2010 | Material : Design2010，31，3： | 1 |
| 16 | Mathematical-physical of the streamer in nonuniform fields显示文摘 | Nasser E Heiszler M | 1974 | Jou Applied Physics1974，45，8： | 1 |
| 17 | Validating the weight gain of preterm infants between the reference growth curve of the fetus and the term infant 显示文摘 | Fenton TR Nasser R Eliasziw M | 2013 | BMC Pediatr2013，13，： | 1 |
| 18 | Little clinical benefit of early systemic aciclour for treatment of primary herpetic stomatitis显示文摘 | Nasser M Fedorouicz Z Khoshnevisan MH | 2008 | Evidence - Based Dentistry2008，4，： | 1 |
| 19 | Developing a transfer function for vehicle ride performance显示文摘 | NASSER M JAWAD B | 2009 | SAE International Journal of Passenger Cars-Mechanical Systems2009，，1： | 1 |
| 20 | Methylation mediated silencing of microRNA-1 gene and its role in hepatocellular carcinogenesis显示文摘 | Datta J Kutay H Nasser M W | 2008 | Cancer Res2008，68，13： | 1 |
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