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| 1 | Trend in gastric cancer:35 years of surgical experience in Japan显示文摘AIM:To investigate the trend in gastric cancer surgery in the context of rapid therapeutic advancement in Japan and East Asia.METHODS:A retrospective analysis was performed on 4163 patients who underwent gastric resection for gastric cancer with histological confirmation between 1971 and 2007 at the surgical unit in Kitasato University Hospital,to determine the trend in gastric cancer requiring surgery.RESULTS:Gastric cancer requiring surgical resection increased in our hospital,but the incidence adjusted for population was constant during the observed pe-riod.Interestingly,the ratio of diffuse type/intestinal type gastric cancer was unexpectedly unchanged,and that of advanced/early gastric cancer(EGC)was,however,markedly reduced,while the actual incidence of potentially curative advanced gastric cancer tended to decrease.The incidence of EGC requiring surgery tended to increase as a whole,which is consistent with increased prevalence of endoscopic surveillance.As a result,overall survival and mortality of gastric cancer requiring gastric resection has recently markedly improved.CONCLUSION:In Japan,planned interventions may improve surgical gastric cancer mortality,but an unexpected trend of persistent existence of intestinal type cancer suggests the need for more robust medical intervention. | Keishi Yamashita Shinichi Sakuramoto Masayuki Nemoto Tomotaka Shibata Hiroaki Mieno Natsuya Katada Shiroh Kikuchi Masahiko Watanabe | 2011 | World Journal of Gastroenterology2011，17，29： | 11 |
| 2 | Delayed perforation after endoscopic submucosal dissection for early gastric cancer: Clinical features and treatment显示文摘Perforation is an important procedural complication of endoscopic submucosal dissection(ESD) for early gastric cancer. Although the incidence of delayed perforation after ESD is low, extreme caution is necessary because many cases require surgical intervention. Among 1984 lesions of early gastric cancer treated in our hospital by ESD in 1588 patients from September 2002 through March 2015, delayed perforation developed in 4 patients(4 lesions, 0.25%). A diagnosis of delayed perforation requires prompt action, including surgical intervention when required. | Takafumi Yano Satoshi Tanabe Kenji Ishido Mizutomo Azuma Takuya Wada Mizuto Suzuki Natsuko Kawanishi Sakiko Yamane Tohru Sasaki Chikatoshi Katada Tetsuo Mikami Natsuya Katada Wasaburo Koizumi | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，8： | 4 |
| 3 | Macroscopic appearance of TypeⅣand giant Type Ⅲ is a high risk for a poor prognosis in pathological stage Ⅱ/Ⅲ advanced gastric cancer with postoperative adjuvant chemotherapy显示文摘AIM To evaluate whether a high risk macroscopic appearance(Type Ⅳ and giant Type Ⅲ) is associated with a dismal prognosis after curative surgery, because its prognostic relevance remains elusive in pathological stage Ⅱ/Ⅲ(p Stage Ⅱ/Ⅲ) gastric cancer.METHODS One hundred and seventy-two advanced gastric cancer(defined as pT2 or beyond) patients with p Stage Ⅱ/Ⅲ who underwent curative surgery plus adjuvant S1 chemotherapy were evaluated, and the prognostic relevance of a high-risk macroscopic appearance was examined. RESULTS Advanced gastric cancers with a high-risk macroscopic appearance were retrospectively identified by preoperative recorded images. A high-risk macroscopic appearance showed a significantly worse relapse free survival(RFS)(35.7%) and overall survival(OS)(34%) than an average risk appearance(P = 0.0003 and P < 0.0001, respectively). A high-risk macroscopic appearance was significantly associated with the 13^(th) Japanese Gastric Cancer Association(JGCA) pT(P = 0.01), but not with the 13^(th) JGCA pN. On univariate analysis for RFS and OS, prognostic factors included 13^(th) JGCA p Stage(P < 0.0001)and other clinicopathological factors including macroscopic appearance. A multivariate Cox proportional hazards model for univariate prognostic factors identified highrisk macroscopic appearance(P = 0.036, HR = 2.29 for RFS and P = 0.021, HR = 2.74 for OS) as an independent prognostic indicator. CONCLUSION A high-risk macroscopic appearance was associated with a poor prognosis, and it could be a prognostic factor independent of 13^(th) JGCA stage in p Stage Ⅱ/Ⅲ advanced gastric cancer. | Keishi Yamashita Akira Ema Kei Hosoda Hiroaki Mieno Hiromitsu Moriya Natsuya Katada Masahiko Watanabe | 2017 | World Journal of Gastrointestinal Oncology2017，9，4： | 2 |
| 4 | Short-term and long-term outcome of endoluminal gastroplication for the treatment of GERD: the first multicenter trial in Japan显示文摘 | Soji Ozawa Koichiro Kumai Kazuhide Higuchi Tetsuo Arakawa Mototsugu Kato Masahiro Asaka Natsuya Katada Hiroyuki Kuwano Masaki Kitajima | 2009 | Journal of Gastroenterology2009，，7： | 1 |
| 5 | Advances in surgical treatment for GERD 显示文摘 | Natsuya Katada | 2007 | 28 ( 10 ) :456-4582007，28，10： | 1 |
| 6 | Transfusion Alert for Patients with Curable Cancer显示文摘 | Keishi Yamashita Shinichi Sakuramoto Shiroh Kikuchi Natsuya Katada Nobuyuki Kobayashi Masahiko Watanabe | 2007 | World Journal of Surgery2007，，12： | 1 |
| 7 | Duodenoesophageal Reflux Induces Apoptosis in Rat Esophageal Epithelium显示文摘 | Natsuya Katada Ronald A. Hinder Thomas C. Smyrk Yoshiki Hiki Akiri Kakita | 1999 | Digestive Diseases and Sciences1999，，2： | 1 |
| 8 | Definitive Chemoradiation Therapy With Docetaxel, Cisplatin, and 5-Fluorouracil (DCF-R) in Advanced Esophageal Cancer: A Phase 2 Trial (KDOG 0501-P2)显示文摘 | Katsuhiko Higuchi Shouko Komori Satoshi Tanabe Chikatoshi Katada Mizutomo Azuma Hiromichi Ishiyama Tohru Sasaki Kenji Ishido Natsuya Katada Kazushige Hayakawa Wasaburo Koizumi | 2014 | International Journal of Radiation Oncology Biology Physics2014，，： | 1 |
| 9 | A phase II study of endoscopic submucosal dissection for superficial esophageal neoplasms (KDOG 0901)显示文摘 | Katsuhiko Higuchi Satoshi Tanabe Mizutomo Azuma Chikatoshi Katada Tohru Sasaki Kenji Ishido Akira Naruke Natsuya Katada Wasaburo Koizumi | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
| 10 | Laparoscopy-assisted distal gastrectomy for early gastric cancer with complete situs inversus: Report of a case显示文摘 | Nobue Futawatari Shiro Kikuchi Hiromitsu Moriya Natsuya Katada Shinichi Sakuramoto Masahiko Watanabe | 2010 | Surgery Today2010，，1： | 1 |
| 11 | Which patients with advanced, proximal gastric cancer benefit from complete clearance of spleno-pancreatic lymph nodes显示文摘 | Kikuchi S Nemoto Y Natsuya K | 2002 | Anticancer Res2002，22，6： | 1 |
| 12 | Important role of energy- dependent mitochondrial pathways in cultured rat cardiac myocyte apoptosis显示文摘 | Tetsuya Tatsumi Natsuya Keira | 2000 | Am J Physiol Circ Physiol2000，281，： | 1 |
| 13 | Intratumoral lymphangio- genesis of esophageal squamous cell carcinoma and relationship with regulatory factors and prognosis显示文摘 | Akemi I Hiromitsu M Natsuya K | 2008 | Pathology International2008，58，10： | 1 |
| 14 | A phase II study of endoscopic submucosal dissection for superficial esophageal neoplasms显示文摘 | Katsuhiko Higuchi Satoshi Tanabe Mizutomo Azuma Chikatoshi Katada Tohru Sasaki Kenji Ishido Akira Naruke Natsuya Katada Wasaburo Koizumi | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
| 15 | Which patients with advanced, proximal gastric cancer henefit from complete clearance of spleno-panereratic lymph nodes 显示文摘 | Kikuchi S Nemoto Y Natsuya K | 2002 | Anticancer Res2002，22，6： | 1 |
| 16 | Cardioprotective effect of angiotension-converting enzyme inhibition against hypoxia /reoxygeneration injury in cultured rat cardiac myocytes显示文摘 | SATOAKI M TETSUYA T NATSUYA K | 1999 | Circulation1999，99，6： | 1 |
| 17 | A phase II study of endoscopic submucosal dissection for superficial esophageal neoplasms (KDOG 0901)显示文摘 | Katsuhiko Higuchi Satoshi Tanabe Mizutomo Azuma Chikatoshi Katada Tohru Sasaki Kenji Ishido Akira Naruke Natsuya Katada Wasaburo Koizumi | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
| 18 | Clinical Experience of Laparoscopy-Assisted Proximal Gastrectomy with Toupet-Like Partial Fundoplication in Early Gastric Cancer for Preventing Reflux Esophagitis显示文摘 | Shinichi Sakuramoto Keishi Yamashita Shiro Kikuchi Nobue Futawatari Natsuya Katada Hiromitsu Moriya Kazuya Hirai Masahiko Watanabe | 2009 | Journal of the American College of Surgeons2009，，3： | 1 |
| 19 | Technique of esophagojejunostomy using transoral placement of the pretilted anvil head after laparoscopic gastrectomy for gastric cancer显示文摘 | Shinichi Sakuramoto Shiro Kikuchi Nobue Futawatari Hiromitsu Moriya Natsuya Katada Keishi Yamashita Masahiko Watanabe | 2010 | Surgery2010，，5： | 1 |
| 20 | Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial显示文摘 | Shinichi Sakuramoto Keishi Yamashita Shiro Kikuchi Nobue Futawatari Natsuya Katada Masahiko Watanabe Toshiyuki Okutomi Guoqin Wang Leon Bax | 2013 | Surgical Endoscopy2013，，5： | 1 |
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