维普期刊资源整合服务平台（V6.5）

29篇 您的检索式：作者名="Nazli H"

选中清除导出查看参考文献查看引证文献引用追踪共2页首页上一页第1页下一页末页 /2 跳转

	题名	作者	年代	出处	被引量
1	Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier显示文摘More than 40%of HIV infections occur via female reproductive tract(FRT)through heterosexual transmission.Epithelial cells that line the female genital mucosa are the first line of defense against HIV-1 and other sexually transmitted pathogens.These sentient cells recognize and respond to external stimuli by induction of a range of carefully balanced innate immune responses.Previously,we have shown that in response to HIV-1 gp120,the genital epithelial cells(GECs)from upper reproductive tract induce an inflammatory response that may facilitate HIV-1 translocation and infection.In this study,we report that the endometrial and endocervical GECs simultaneously induce biologically active interferon-β(IFNβ)antiviral responses following exposure to HIV-1 that act to protect the epithelial tight junction barrier.The innate antiviral response was directly induced by HIV-1 envelope glycoprotein gp120 and addition of gp120 neutralizing antibody inhibited IFNβproduction.Interferon-βwas induced by gp120 in upper GECs through Toll-like receptor 2 signaling and required presence of heparan sulfate on epithelial cell surface.The induction of IFNβwas dependent upon activation of transcription factor IRF3(interferon regulatory factor 3).The IFNβwas biologically active,had a protective effect on epithelial tight junction barrier and was able to inhibit HIV-1 infection in TZM-bl indicator cells and HIV-1 replication in T cells.This is the first report that recognition of HIV-1 by upper GECs leads to induction of innate antiviral pathways.This could explain the overall low infectivity of HIV-1 in the FRT and could be exploited for HIV-1 prophylaxis.	Aisha Nazli Sara Dizzell Muhammad Atif Zahoor Victor H Ferreira Jessica Kafka Matthew William Woods Michel Ouellet Ali A Ashkar Michel J Tremblay Dawn ME Bowdish Charu Kaushic	2019	Cellular & Molecular Immunology2019，16，2：	2
2	Fatty acids of lamb meat from two breeds fed different forage: concentrate ratio 显示文摘	Demirel G Ozpinar H Nazli B	2006	Meat Science2006，72，：	1
3	Radiation and chemical pretreatment of cellulosic waste显示文摘	Rahayu C Nazly H Erizal	1993	Radiat Phys Chem1993，42，：	1
4	An Improved Design of Planar Elliptical Applications 显示文摘	NAZLI H BICAK E TURETKEN B	2010	IEEE Antennas and Wireless Propagation Letters2010，9，：	1
5	Survival analysis after surgical treatment of gastric cancer:review of 121 cases显示文摘	Nazli O Derici H Tansug T	2007	Hepatogastroenterology2007，54，74：	1
6	Survival analysis after surgical treatment of gastric cancer:review of 121 cases显示文摘	Nazli O Derici H Tansug T	2007	Hepatogastroenterology2007，54，74：	1
7	Detection of presence of cow's milk in sheep's cheeses by immunochromatography显示文摘	COLAK H AYDIN A NAZLI B	2006	Food Control2006，17，：	1
8	HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium 显示文摘	Nazli A Kafka J K Ferreira V H	2013	J Immnnol2013，191，8：	1
9	HIV-1 gpl20 induces TLR2- and TLR4- mediated innate immune activation in human female genital epithelium显示文摘	Nazli A Kafka J K Ferreira V H Anipindi V Muel- ler K Osborne B J Dizzell S Chauvin S Mian M F Ouellet M Tremblay M J Mossman K L Ashkar A A Kovacs C Bowdish D M Snider D P Kaul R Kaushic C	2013	J Immunol2013，191，8：	1
10	An improved design of planar elliptical dipole antenna for UWB applications显示文摘	NAZLI H TURETKEN B SEZGIN M	2010	IEEE Antenna Wireless Propagation Lett2010，，9：	1
11	Acute phase reactants in pa- tients with coronary slow flow phenomenon 显示文摘	Madak N Nazli Y Mergen H	2010	Anadolu Kardiyol Derg2010，10，5：	1
12	An improved de- sign of planar elliptical dipole antenna for UWB applica- tions 显示文摘	Nazli H Bicak E Turetken B	2010	IEEE Antennas Wireless Propag Lett2010，9，：	1
13	Acute phase reactants in pa tients with coronary slow flow phenomenon显示文摘	Madak N Nazli Y Mergen H	2010	Anadolu Kardiy ol Derg2010，10，5：	1
14	The Structure of Informal Credit Market in Paskistan显示文摘	Irfan M Arif D M Ali S M Nazli H	1999	Pakistan Institute of Development Economics1999，，2：	1
15	Acute phase reactants in patients with coronary slow flow phenomenon 显示文摘	Madak N Nazli Y Mergen H	2010	Anadolu Kardiyo! Derg2010，10，5：	1
16	Survival analysis after surgical treatment of gastric cancer: review of 121 cases显示文摘	Nazli 0 Derici H Tansug T	2007	Hepatogastro- enterology2007，54，74：	1
17	Acute phase reactants in pa- tients with coronary slow flow phenomenon显示文摘	Madak N Nazli Y Mergen H	2010	Anadolu Kardiyol Derg2010，10，：	1
18	Prosthetic repair of incarcerated inguinal hemias显示文摘	Derici H Unalp HR Nazli O	2010	Langenbecks Arch Surg2010，395，5：	1
19	Acute phase reactants in patients with coronary slow flow phenomenon显示文摘	Madak N Nazli Y Mergen H		0，，：	1
20	Prosthetic repair of incarcerated inguinal hernias:is it a reliable method显示文摘	Derici H Unalp HR Nazli O		0，，05：	1

返回顶部每页显示：

共2页首页上一页第1页下一页末页 /2 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示