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| 1 | Antihyperglycemic activity,antihyperlipedemic activity,haematological effects and histopathological analysis of Sapindus mukorossi Gaerten fruits in streptozotocin induced diabetic rats显示文摘Objective:To investigate the antihyperglycemic and antihyperlipidemie properties of hydroalcoholic extract of fruits of Sapindus mukorossi Caerlen and its beneficial effect on haeniatological parameters with histopathological analysis in streptpzotocin induced diabetic rats.Methods:Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and standard drug glybenclamide(0.5 mg/kg body weight) were administered to diabetic rats.Effect of extract on hyperglycemia,hyperlipidemia and hematological parameters was studied in diabetic rats.Histopathological changes in diabetic rat pancreas were also observed after extract and glybenclamide treatment.Results:Daily oral administration of Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and glybenclamide for 20 days showed beneficial effects on blood glucose level(P<0.01) and lipid level.The extract has a favorable effect on the histopathological changes of the pancreas in streptozotocin induced diabetes.Conclusions: These findings reveal that the hydroalcoholic extract of Sapindus mukorossi fruits extract possesses antihyperglycemic and antihyperlipidemie properties.In addition.the extract can prevent various complications of diabetes and improve some haeniatological parameters. | Neeraj Verma G Amresh P K Sahu Neelam Mishra Anil P Singh Ch V Rao | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，7： | 14 |
| 2 | Hepatoprotective potential of ethanolic extract of Ziziphus oenoplia(L.)Mill roots against antitubercular drugs induced hepatotoxicity in experimental models显示文摘Objective:To evaluate the hepatoprotective potential of ethanolic(50%) extract of Ziziphus oenoplia(L.) Mill(Z.oenoplia) root against isoniazid(INH) and rifampicin(RIF) induced liver damage in animal models.Methods:Five groups of six rats each were selected for the study.Ethanolic extract at a dose of 150 and 300 mg/kg as well as silymarin(100 mg/kg) were administered orally once daily for 21 d in INH + RIF treated groups.The serum levels of glutamic oxaloacetic transaminase(SGOT),glutamate pyruvate transaminase(SGPT),alkaline phosphatase (SALP),and bilirubin were estimated along with activities of superoxide dismutase,catalase, glutathione S-transferase,glutathione peroxidase,and hepatic melondialdehyde formation. Histopathological analysis was carried out to assess injury to the liver.Result:The considerably elevated serum enzymatic activities of glutamic oxaloacetic transaminase,glutamate pyruvate transaminase,alkaline phosphatase and bilirubin due to INH + RIF treatment were restored towards norma) in a dose dependent manner after the treatment with ethanolic extract of Z.oenoplia roots.Meanwhile,the decreased activities of superoxide dismutase,catalase, glutathione S-transferase and glutathione peroxidase were also restored towards normal dose dependency.In addition,ethanolic extract also significantly prevented the elevation of hepatic melondialdehyde formation in the liver of INH + RIF intoxicated rats in a dose dependent manner. The biochemical observations were supplemented with histopathological examination of rat liver sections.Conclusions:The results of this study slrongly indicate that ethanolic extract of Z.oenoplia has a potent hepatoprotective action against INH + RIF induced hepatic damage in rats. | Ch V Rao AKS Rawat Anil P Singh Arpita Singh Neeraj Verma | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，4： | 6 |
| 3 | Biosorptionof Chromium (Vl) from Aqueous Solutions by Green Algae Spirogyra Species显示文摘 | Gopta V K Shfivastava A K Neeraj Jain | 2001 | Water Research2001，35，17： | 1 |
| 4 | Antihyperglycemic and antihyperlipidemic activity of ethyl acetate fraction of Rhododendron arboreum Smith flowers in streptozotocin induced diabetic rats and its role in regulating carbohydrate metabolism显示文摘Objective:To explore and identify the most potent antihyperglycemic fraction from the ethanol extract of Rhododendron arboreum(R.arboreum)flowers.Methods:Normal and streptozotocin induced diabetic rats were treated with all four fractions of R.arboreum flowers for short term and with fraction 3 for long term study.On completion of the treatment,a range of indicators were tested including fasting blood glucose,plasma protein,haemoglobin A1C,insulin secretion,body weight,blood lipid profile and carbohydrate metabolism regulating enzymes of liver.Results:In short term study,the fraction 3(Active fraction)produced a significant(P<0.0001)reduction(73.6%)in blood glucose level at a dose of 200 mg/kg after the treatment in the diabetic rats.Administration of active fraction(200 and 400 mg/kg)once daily for 30 d in streptozotocin diabetic rats resulted in a significant(P<0.001 to P<0.0001)fall in blood glucose level,hemoglobin A1C,serum urea and creatinine with significant but a increase in insulin level similar to standard drug glybenclamide.Further,the active fraction showed antihyperlipidemic activity as evidenced by significant(P<0.001 to P<0.0001)decreases in serum serum total cholesterol,triglycerides,low density lipoprotein cholesterol and very low density cholesterol levels coupled together with elevation of high density lipoprotein cholesterol in the diabetic rats.Conclusions:The active fraction of R.arboreum flowers decreases streptozotocin induced hyperglycemia by promoting insulin secretion and glycolysis and by decreasing gluconeogenesis. | Neeraj Verma G Amresh PK Sahu Ch V Rao Anil Pratap Singh | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，9： | 1 |
| 5 | Photooxidative damage to the cyanobacterium Spirulina platensis mediated by singlet oxygen显示文摘 | Singh D P Neeraj S Kavita V | 1995 | Current Microbiol1995，31，1： | 1 |
| 6 | Time to rethink: anevidence-based response from pelvic surgeons to the FDA Safety Communication: 'UPDATE on Serious Complications Associated with Transvaginal Placement of Surgical Mesh for Pelvic Organ Prolapse' 显示文摘 | Adam H Heather V R Neeraj K | 2012 | Int Urogyneeol J2012，23，1： | 1 |
| 7 | Pediatric and adult primary sarcomas of the kidney:a cross-sectional imaging review显示文摘 | Neeraj L Srinivasa RP Raghu V | | 0，，： | 1 |
| 8 | Oxalis leaf curl-A new report from Aligarh, India显示文摘 | Doomar S Neeraj V Naqvi Q A | 1999 | Indian Journal of Virology1999，15，2： | 1 |
| 9 | Pediatric and adult primary sarcomas of the kidney:a cross-sectional imaging review显示文摘 | Neeraj L Srinivasa RP Raghu V | | 0，，： | 1 |
| 10 | Multi-detector row CT in evaluation of 94 living renal donors by readers with varied experience显示文摘 | Dushyant V Neeraj R Alan C | 2005 | Radiology2005，235，3： | 1 |
| 11 | Biodegradable block copolymers显示文摘 | Neeraj K Majeti N V Ravikumar | 2001 | Advanced Drug Delivery Reviews2001，53，1： | 1 |
| 12 | A compact spark pre-ionized pulser sustainer TE-CO2 laser显示文摘 | Benerji N S Neeraj V Lala A | 2004 | Sadhana2004，29，： | 1 |
| 13 | Biosorption of chromium (VI) from aqueous solutions by green algae spirogyra species显示文摘 | Gupta V K Shrivastava A K Neeraj Jain | 2001 | Wat Res2001，35，： | 1 |
| 14 | Biosorption of Chromium(VI) from Aqueous Solutions by Green Algae Spirogyra Species显示文摘 | Shrivastava A K Neeraj Jain | 2001 | Water Research2001，35，17： | 1 |
| 15 | Clinical advantages of cartilage palisades over temporalis fascia in type I tympanoplasty显示文摘 | ASHISH V NEERAJ NARAYAN M SANTOSHA RAM C | 2014 | Auris Nasus Larynx2014，41，5： | 1 |
| 16 | Biodegradable block copolymers 显示文摘 | K Neeraj N V Ravikumar Majeti A J Domb | 2001 | Advanced Drag Delivery Reviews2001，53，23： | 1 |
| 17 | Biosorption of chromium(Ⅵ) from aqueous solutions by green Spirogyraspecies显示文摘 | Gupta V K Shrivastara A K Neeraj J | 2001 | War Res2001，35，7： | 1 |
| 18 | Biosorption of chromium(Ⅵ)from aqueous solutions by green algae spirogyra species显示文摘 | Gupta V K Shrivastava A K Neeraj Jain | 2001 | Wat Res2001，35，17： | 1 |
| 19 | Biodegradable block copolymers显示文摘 | N V Ravikumar Majeti A J Domb | 2001 | Advanced Drag Delivery Reviews2001，53，1： | 1 |
| 20 | Prenatal radiographic evaluation of congenital transverse limb deficiencies:A scoping review显示文摘BACKGROUND Congenital transverse deficiencies are horizontal deficiencies of the long bones that occur with a reported incidence as high 0.38%.They can occur alone or represent a manifestation of a various clinical syndromes.Diagnosis has tradi-tionally comprised of conventional radiography and prenatal imaging studies.There has been much advancement regarding prenatal imaging modalities to allow for early diagnosis and appropriate treatment.AIM To summarize the current state of knowledge on congenital transverse limb deficiencies and to provide an update regarding the radiographic evaluation of congenital transverse limb deficiencies.METHODS This IRB-exempt scoping review followed the PRISMA-ScR checklist for scoping reviews strictly.Five search engines were searched for a total of 265 publications.Four authors reviewed these during the screening process.Of these,51 studies were included in our article.Prenatal magnetic resonance imaging(MRI),3D Ultrasound,and multidetector Computed tomography(CT)exist are emerging modalities that have the potential to improve diagnosis.RESULTS Use of the appropriate classification system,three-dimensional ultrasonography with a maximum intensity projection,and appropriate use of prenatal MRI and prenatal CT can improve diagnosis and inter-provider communication.CONCLUSION Further scholarly efforts are required to develop improve standardized guidelines regarding the pre-natal radiographic evaluation of congenital limb deficiencies. | Neeraj Vij Luis F Goncalves Aaron Llanes Sean Youn Mohan V Belthur | 2023 | World Journal of Orthopedics2023，14，3： | 0 |
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