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| 1 | Direct injection HILIC-MS/MS analysis of darunavir in rat plasma applying supported liquid extraction显示文摘A novel bioanalytical method was developed and validated for the quantitative determination of darunavir(DRV) in rat plasma by employing hydrophilic interaction chromatography and tandem mass spectrometry(HILIC-MS/MS) with supported liquid extraction(SLE).lrbesartan(IRB) was used as an internal standard(IS).The analyte in rat plasma(200 μL) was isolated through SLE using ethyl acetate as the eluting solvent.The chromatographic separation was achieved on Luna-HILIC(250 mm × 4.6 mm,5 μm)column with a mobile phase of 0.1% of formic acid in water:acetonitrile(5:95,v/v),at a constant flow rate of 1.0mL/min.The MS/MS ion transitions for DRV(548.1→392.0) and IS(429.2→207.1) were monitored on an ion trap mass spectrometer,operating in the multiple reaction monitoring(MRM) mode.The lower limit of quantitation(LLOQ) was 0.2 ng/mL and quantitation range was 0.2-5000 ng/mL.The method was validated for its selectivity,sensitivity,carryover,linearity,precision,accuracy,recovery,matrix effect and stability.The method was successfully applied to pharmacokinetic study in rats. | Bokka Ramesh Nemali Manjula Sistla Ramakrishna Potturi Sita Devi | 2015 | Journal of Pharmaceutical Analysis2015，5，1： | 2 |
| 2 | Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3- hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators显示文摘 | Reddy J K Goel S K Nemali M R | 1986 | Proc Natl Acad Sci USA1986，83，6： | 1 |
| 3 | An automated system for controlling drought stress and irrigation in potted plants显示文摘 | Krishna S. Nemali Marc W. van Iersel | 2006 | Scientia Horticulturae2006，，3： | 1 |
| 4 | Calibration and performance of moisture sensors in soilless substrates:ECHz O and Theta probes显示文摘 | Nemali K S Montesano F Dove S K | 2007 | Scientia Horticulturae2007，112，： | 1 |
| 5 | An automated system for controlling drought stress and irrigation in potted plants显示文摘 | Nemali K S Van Iersel M | 2006 | Scientia Horticulturae2006，3，110： | 1 |
| 6 | Nanocrystalline Magnesium Oxide as a Versatile Heterogeneous Catalyst for the Meerwein-Ponndorf-Verley Reduction of Cyclohexanone into Cyclohexanol: Effect of Preparation Method of Magne- sium Oxide on Yield显示文摘 | Heidari H Abedini M Nemali A | 2009 | CatalLett2009，130，12： | 1 |
| 7 | Calibration and performance of moisture sensors in soillesssubstrates: ECH20 and Theta probes显示文摘 | Krishna S Nemali Francesco Montesano Sue K Dove | 2007 | Scientia Horticulture2007，112，2： | 1 |
| 8 | Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators 显示文摘 | Reddy J K Goel S K Nemali M R | 1986 | Proc Natl Acad Sci1986，83，： | 1 |
| 9 | LC–HRMS determination of piperine on rat dried blood spots: A pharmacokinetic study显示文摘A liquid chromatography–high resolution mass spectrometry(LC–HRMS) method was developed and validated for the determination of piperine(PPR) on dried blood spots(DBS). DBS samples were prepared by spiking the whole blood with analyte to produce 30 m L of blood spots on specimen collection cards.Chromatographic separation was achieved on an Atlantis d C18 column using acetonitrile and water(0.1%formic acid)(85:15, v/v) as mobile phase in an isocratic mode of elution at a flow rate of 0.75 m L/min. MS detection was carried out in electrospray positive ion mode for the target ions and monitored at m/z286.1465 for PPR and 272.1303 for the internal standard(IS). The developed method exhibited a linear dynamic range over 0.01–2000 ng/m L for PPR on DBS. The overall extraction recovery of PPR from DBS was 92.5%. Influence of hematocrit and spot volume on DBS was also evaluated and found to be well within the acceptable limits. The method was successfully applied to pharmacokinetic studies of PPR in rats. | Bokka Ramesh P. Rajesh Rao Vadaparthi Genji Sukumar Nemali Manjula Katragadda Suresh Babu Potturi Sita Devi | 2016 | Journal of Pharmaceutical Analysis2016，6，1： | 1 |
| 10 | An automated system for controlling drought stress and irrigation in potted plants显示文摘 | Kfishna S Nemali Marc W van Iersel | 2006 | Scientia Horticulturae2006，110，3： | 1 |
| 11 | An automated system for controlling drought stress and irrigation in potted plants显示文摘 | Nemali K S van Iersel M W | 2006 | i entia Hortieulturae2006，110，3： | 1 |
| 12 | Fertilizer Concentration and Irrigation Method Affect Growth and Fruiting of Ornamental Pepper显示文摘 | Kang J G Iersel M W Nemali K S | 2004 | Journal of Plant Nutrition2004，27，5： | 1 |
| 13 | Comparison of constitutive and inducible levels of expression of peroxisomal beta-oxidation and catalase genes in liver and extrahepatic tissues of rat显示文摘 | Nemali MR Usuda N Reddy MK | 1988 | Cancer Res1988，48，： | 1 |
| 14 | Calibra- tion and performance of moisture sensors in soilless substrates: ECH20 and Theta probes 显示文摘 | Nemali K S Montesano F Dove S K | 2007 | Seientia Hortieulturae2007，112，2： | 1 |
| 15 | Acclimation of wax begonia to light intensity:changes in photosynthesis,respiration,andchlorophyII concentration显示文摘 | Krishna X Nemali M W Van I | 2004 | Journal of the American Society for Horticultural Science2004，129，5： | 1 |
| 16 | Acclimation of wax begonia to light intensity: Changes in photosynthesis, respiration, and chlorophyll concentration 显示文摘 | NEMALI K S VAN LERSEL M W | 2004 | Amer Soc Hort Sci2004，129，5： | 1 |
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