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| 1 | The performance characteristics of prostate-specific antigen and prostate-specific antigen density in Chinese men显示文摘我们在中国人调查了前列腺特定的抗原(PSA ) 和 PSA 密度(PSAD ) 的表演特征。经历了 transrectal 的所有中国人到 2013 的从 2000 年的指导超声的前列腺活体检视(TRUS-PB ) 被包括。为 PSA 和 PSAD 操作特征(巨鸟) 曲线的接收装置被分析。敏感,特性,积极预兆的价值(PPV ) 和在不同截止层次的否定预兆的价值(NPV ) 是计算的。2606 个中国人的一个总数被包括。为 ROC,在曲线下面的区域为 PSA 是 0.770 (P <0.001 ) 并且 0.823 为 PSAD (P <0.001 ) 。4.5 ng ml −1 的 PSA 94.4% 的有的敏感, 14.1% 的特性, 29.5% 的 PPV,和 86.9% 的 NPV;0.12 ng ml −1 cc −1 的 PSAD 有 94.5% 的敏感, 26.6% 的特性, 32.8% 的 PPV,和 92.7% 的 NPV。在逻辑回归分析的 multivariate 上,在 4.5 ng ml −1 截止的 PSA (或 1.61, 95% CI 1.05-2.45, P = 0.029 ) 并且在 0.12 ng ml −1 cc 截止的 PSAD −1( 或 6.22, 95% CI 4.20-9.22, P <0.001 ) 是为 TRUS-PB 上的前列腺癌症察觉的重要预言者。在结论,在在中国人的不同截止层次的 PSA 和 PSAD 的表演与在白种人的那些很不同。4.5 ng ml −1 的 PSA 和 0.12 ng ml −1 cc −1 的 PSAD 在 95% 敏感附近有并且是在中国人的前列腺癌症察觉的重要预言者。 | Jeremv YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 13 |
| 2 | Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized, double-blind study in urban Asia显示文摘AIM:Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with NERD.METHODS: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms noted.RESULTS: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated. | KM Fock EK Teo TL Ang TS Chua TM Ng YL Tan | 2005 | World Journal of Gastroenterology2005，11，20： | 8 |
| 3 | 经直肠超声引导下穿刺活检诊断前列腺癌与直肠指检和前列腺特异性抗原水平的关系:在中国人群中的情况如何?显示文摘我们分析了经直肠超声引导下穿刺活检后前列腺癌的检出率与直肠指检和前列腺特异性抗原水平的关系以及中国人群检出前列腺癌的危险因素。我们从数据库中检索了自2000年到2013年所有首次接受经直肠超声引导下前列腺穿刺活检的中国男性的数据。结合直肠指检的发现以及前列腺特异性抗原水平(〈 4, 4-10, 10.1-20,20.1-50 , 〉 50ng/ml)分析了前列腺癌的检出率。使用多因素Logistic回归研究了前列腺癌检出的潜在危险因素。共有2606中国男性人群纳入该研究。在直肠指检正常的患者中,不同前列腺特异性抗原水平(〈 4, 4-10,10.1-20, 20.1-50, 〉 50 ng/ml)患者前列腺癌的检出率分别为8.6%,13.4%,21.8%,41.7%和85.2%。在直肠指检异常的患者中,不同前列腺特异性抗原水平(〈 4, 4-10, 10.1-20, 20.1-50, 〉 50 ng/ml)患者前列腺癌的检出率分别为12.4%, 30.2%, 52.7%, 80.6%和96.4%。多因素Logistic回归分析提示:老龄、较小的前列腺体积、更多针数的穿刺活检、直肠指检异常发现、较高的PSA水平都与增大的前列腺癌检出风险相关(P 〈0.001)。与西方人群相比,中国男性人群的前列腺癌检出率较低。考虑到不同的危险因素,可以采用个体化的方式来决定是否采取经直肠超声引导下穿刺活检。 | Jeremy YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho Ming-Kwong Yiu | 2015 | Asian Journal of Andrology2015，17，5： | 4 |
| 4 | Systemic Candida infection in U niversity hospital 1997-1999: the distribution of candida biotypes and antifungal susceptibility patterns显示文摘 | Ng KP Saw TL Na SL | 2001 | Mycopathologia2001，149，3： | 1 |
| 5 | Determination oi cagA, ice A,and vacA genotypes in patients irorn area oi high population prevalence of Helicobacter pylori infection 显示文摘 | Ng NKW Lam YH Cover TL | 1997 | Gut1997，，： | 1 |
| 6 | Inhibition of human immunodeficiency virus type 1 reverse transcriptase,protease and integrase by bovine milk proteins显示文摘 | Lam TL Au TK | 2001 | Life Sci2001，69，19： | 1 |
| 7 | Usefulness of the MicroSeq 500 16S ribosomal DNA-based bacterial identification system for identification of clinically significant bacterial isolates with ambiguous biochemical profiles 显示文摘 | Woo PC Ng KH Lau SK Yip KT Fung AM Leung KW Tam DM Que TL Yuen KY | 2003 | J Clin Microbiol2003，41，5： | 1 |
| 8 | Usefulness of the MicroSeq 500 16S rDNA bacterial identification system for identifica- tion of anaerobic Gram positive bacilli isolated from blood cultures 显示文摘 | Lau SK Ng KH Woo PC Yip KT Fung AM Woo GK than KM Que TL Yucn KY | 2006 | J Clin Pathol2006，59，2： | 1 |
| 9 | Survey of depression by Beck Depression Inventory in uremic patients undergoing hemodialysis and hemodiafiltration显示文摘 | Su SF Ng HY Huang TL | 2012 | Ther Apher Dial2012，16，6： | 1 |
| 10 | Aprepitant versus dexamethasone to prevent delayed emesis after chemo- therapy显示文摘 | Ng TL Clemons M Hutton B | 2014 | J Clin Oncol2014，32，20： | 1 |
| 11 | Candida biotypes iso- lated from clinical specimens in Malaysia显示文摘 | Ng KP Madasamy M Saw TL | 1998 | Myeopathologia1998，144，13： | 1 |
| 12 | A comparison of HIV-1 integrase in- hibition by aqueous and methanol extracts of Chinese medicinal herbs 显示文摘 | Au TK Lam TL Ng TB | 2001 | Life Sci2001，，68： | 1 |
| 13 | A comparison Of HIV-1 integrase inhibition by aqueous and methanal extracts of Chinese medicine herbe显示文摘 | Au TK Lam TL Ng TB | | 0，，68： | 1 |
| 14 | Six month radiological and physiological outcomes in severe acute respiratory syndrome (SARS)survivors显示文摘 | NG CK CHAN JW KWAN TL | 2004 | Thorax2004，59，： | 1 |
| 15 | Nuclear beta-catenin in mesenchymai tumors显示文摘 | Ng TL Gown AM Barry TS | 2005 | Mod Pathol2005，18，1： | 1 |
| 16 | Current status of robot-assisted surgery显示文摘 | Ada TL Ng Tam PC | 2014 | HongKong Med J2014，20，3： | 1 |
| 17 | Nursing intervention to enhance efficacy of home practice of pelvic floor muscle exercises in treating mixed urinary incontinence 显示文摘 | Ng SC Lin TL Chang SJ | 2008 | Int Urogynecol J Pelvic Floor Dysfunt2008，19，5： | 1 |
| 18 | Nursing intervention to enhance efficacy of home practice of pelvic floor muscle exercises in treating mixed urinary incontinence显示文摘 | Ng SC Lin TL Chang SJ | 2008 | Int Urogynecol J2008，19，： | 1 |
| 19 | Immunoglobulin G4-related sclerosing disease:experience with this novel entity in a local hospital显示文摘 | Ng TL Leong IS Tang WL | 2011 | Hong Kong Med J2011，17，4： | 1 |
| 20 | Diagnosis of a metastatic phyllodes tumor of the pancreas using EUS-FNA显示文摘 | Ang TL Ng VW Fock KM | 2007 | JOP2007，8，1： | 1 |
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