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| 1 | Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine. | Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu | 2021 | World Journal of Transplantation2021,11,4: | 2 |
| 2 | Thermal hypersensitivity in a subset of irritable bowel syndrome patients显示文摘AIM:To characterize thermal hypersensitivity in patients with constipation-and diarrhea-predominant irritable bowel syndrome (IBS).METHODS:Thermal pain sensitivity was tested among patients with diarrhea-predominant IBS (D-IBS) and constipation-predominant IBS (C-IBS) compared to healthy subjects.A total of 42 patients (29 female and 13 male;mean age 27.0±6.4 years) with D-IBS;24 patients (16 female and eight male;mean age 32.5±8.8 years) with C-IBS;and 52 control subjects (34 female and 18 male;mean age 27.3±8.0 years) participated in the study.Thermal stimuli were delivered using a Medoc Thermal Sensory Analyzer with a 3 cm × 3 cm surface area.Heat pain threshold (HPTh) and heat pain tolerance (HPTo) were assessed on the left ventral forearm and left calf using an ascending method of limits.The Functional Bowel Disease Severity Index (FBDSI) was also obtained for all subjects.RESULTS:Controls were less sensitive than C-IBS and D-IBS (both at P < 0.001) with no differences between C-IBS and D-IBS for HPTh and HPTo.Thermal hyperalgesia was present in both groups of IBS patients relative to controls,with IBS patients reporting significantly lower pain threshold and pain tolerance at both test sites.Cluster analysis revealed the presence of subgroups of IBS patients based on thermal hyperalgesia.One cluster (17% of the sample) showed a profile of heat pain sensitivity very similar to that of healthy controls;a second cluster (47% of the sample) showed moderate heat pain sensitivity;and a third cluster (36% of the sample) showed a very high degree of thermal hyperalgesia.CONCLUSION:A subset of IBS patients had thermal hypersensitivity compared to controls,who reported significantly lower HPTh and HPTo.All IBS patients had a higher score on the FBDSI than controls.Interestingly,the subset of IBS patients with high thermal sensitivity (36%) had the highest FBDSI score compared to the other two groups of IBS patients. | QiQi Zhou Roger B Fillingim Joseph L Riley Ⅲ G Nicholas Verne | 2009 | World Journal of Gastroenterology2009,15,26: | 2 |
| 3 | Diameter-selective encapsulation of metallocenes in single walled carbon nanotubes 显示文摘 | Li L J Khlobystov A N Wiltshire J G Briggs G A D Nicholas R J | 2005 | Nature Materials2005,4,: | 1 |
| 4 | Recent improvements to the SMART domain-based sequence annotation resource显示文摘 | Ivica L Leo G Nicholas JD | 2002 | Nucleic Acids Research2002,30,: | 1 |
| 5 | Field and laboratory studies of Desmodora cazca Gerlach,1956 (Desmodoridae:Nematoda) from mangrove mud-flats显示文摘 | Nicholas W L Stewart A C Marples T G | 1988 | Nematologica1988,34,3: | 1 |
| 6 | Diameter-selective encapsulation of metallocenes in single walled carbon nanotubes 显示文摘 | Li L J Khlobystov A N Wiltshire J G Briggs G A D Nicholas R J | 2005 | Nature Materials2005,4,: | 1 |
| 7 | Efeets of initial ischemia/reperfusion injury on the transplanted kidney 显示文摘 | Nicholas L T Ronald D G | 1997 | Transplantation1997,64,: | 1 |
| 8 | Lagrange constraints for transient finite element surface contact 显示文摘 | Carpenter Nicholas J Taylor Robert L Katona Michael G | 1991 | International Journal for Numerical Methods in Engineering1991,32,1: | 1 |
| 9 | Clinical indications for noninvasive positive pressure ventilation in chronic respiratory failure due to restrictive lung disease,COPD,and nocturnal hypoventilation -a consensus conference report显示文摘 | Allen G Patrick L Nicholas H | | 0,,2: | 1 |
| 10 | Development and validation of an air-to-beef food chain model for dioxin-like compounds 显示文摘 | Lohmann R Robert G M L Nicholas J L | 2000 | Science of The Total Environment2000,,156: | 1 |
| 11 | Pres- sure welding by rolling at elevated temperatures显示文摘 | VAIDYANATH L R NICHOLAS M G MILNER D R | 1959 | British WeldJournal1959,6,: | 1 |
| 12 | Neighborhood Evaluation of Local Government Services : A Citizen Survey Approach 显示文摘 | NICHOLAS P L J THOMAS T J G | 1976 | Urban Affairs Review1976,12,2: | 1 |
| 13 | Acid-catalyzed alcoholysis of soybean oil显示文摘 | MICHAEL J G NICHOLAS S B SHAILESH L | 2004 | JAOCS2004,81,4: | 1 |
| 14 | A Fast XPS study of the surface chemistry of ethanol over Pt{1 1 1} 显示文摘 | Adam F L David E G Nicholas J H | 2004 | Surf Sci2004,548,: | 1 |
| 15 | Genetic profile of 22 pancreatic carcinoma cell lines显示文摘 | Patrick S. Moore Bence Sipos Simonetta Orlandini Claudio Sorio Francisco X. Real Nicholas R. Lemoine Thomas Gress Claudio Bassi Günter Kl?ppel Holger Kalthoff Hendrik Ungefroren Matthias L?hr Aldo Scarpa | 2001 | Virchows Archiv2001,,6: | 1 |
| 16 | Pressure welding by rolling at elevated temperatures显示文摘 | Vaidyanath L R Nicholas M G Milner D R | 1959 | British Weld Journal1959,6,: | 1 |
| 17 | Hybrid diffractive-refractive lenses and achromats显示文摘 | Thomas S Wood A P Carmina L Opt 1992 Nicholas G | 1988 | Appl Opt1988,27,14: | 1 |
| 18 | Model systems from life's origins to a synthetic biology显示文摘 | NICHOLAS V H DAVID G L | 2004 | Current Opinion in Chemical Biology2004,8,: | 1 |
| 19 | 显示文摘 | TURNER G W JOHNSTON R L NICHOLAS T W | 2000 | J Chem Phys2000,112,10: | 1 |
| 20 | Do left ventricular assist device (LVAD) bridge-to-transplantation outcomes predict the results of permanent LVAD implantation?显示文摘 | Jose L Navia Patrick M McCarthy Katherine J Hoercher Nicholas G Smedira Michael K Banbury Eugene H Blackstone | 2002 | The Annals of Thoracic Surgery2002,,6: | 1 |