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| 1 | Towards integrated surveillance-response systems for the prevention of future pandemics显示文摘Most human pathogens originate from non-human hosts and certain pathogens persist in animal reservoirs.The transmission of such pathogens to humans may lead to self-sustaining chains of transmission.These pathogens represent the highest risk for future pandemics.For their prevention,the transmission over the species barrier—although rare—should,by all means,be avoided.In the current COVID-19 pandemic,surprisingly though,most of the current research concentrates on the control by drugs and vaccines,while comparatively little scientific inquiry focuses on future prevention.Already in 2012,the World Bank recommended to engage in a systemic One Health approach for zoonoses control,considering integrated surveillance-response and control of human and animal diseases for primarily economic reasons.First examples,like integrated West Nile virus surveillance in mosquitos,wild birds,horses and humans in Italy show evidence of financial savings from a closer cooperation of human and animal health sectors.Provided a zoonotic origin can be ascertained for the COVID-19 pandemic,integrated wildlife,domestic animal and humans disease surveillance-response may contribute to prevent future outbreaks.In conclusion,the earlier a zoonotic pathogen can be detected in the environment,in wildlife or in domestic animals;and the better human,animal and environmental surveillance communicate with each other to prevent an outbreak,the lower are the cumulative costs. | Jakob Zinsstag Jürg Utzinger Nicole Probst-Hensch Lv Shan Xiao-Nong Zhou | 2020 | Infectious Diseases of Poverty2020，9，5： | 3 |
| 2 | Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex显示文摘 | Jürg Müller Craig M. Hart Nicole J. Francis Marcus L. Vargas Aditya Sengupta Brigitte Wild Ellen L. Miller Michael B. O’Connor Robert E. Kingston Jeffrey A. Simon | 2002 | Cell2002，，2： | 1 |
| 3 | The basis of immunogenicity of endocrine allografts 显示文摘 | Nicolls MR Coulombe M Gill RG | 2001 | Crit Rev Immunol2001，21，13： | 1 |
| 4 | Thresholding of statistical maps in functional neuroimaging using the false discovery rate显示文摘 | Christopher RG Nicole AL Thomas EN | 2002 | NeuroImage2002，15，4： | 1 |
| 5 | Accurate Molecular Classification of Kidney Cancer Subtypes Using MicroRNA Signature显示文摘 | Youssef M. Youssef Nicole M.A. White J?rg Grigull Adriana Krizova Christina Samy Salvador Mejia-Guerrero Andrew Evans George M. Yousef | 2011 | European Urology2011，，5： | 1 |
| 6 | Adolescents' awareness of cancer risk factors and associations with health-related behaviours显示文摘 | Kyle RG Nicoll A Forbat L | 2013 | Health Educ Res2013，28，5： | 1 |
| 7 | Local anesthetics and mode of delivery: bupivacaine versus ropivacaine versus levobupivacaine显示文摘 | Yaakov B Nicole RG Howard HB | 2007 | Anesth Analg2007，105，3： | 1 |
| 8 | Variant Creutzfeidz-Jakob diso- ase in UK children: a national surveillance study显示文摘 | Verity CM Nicoll A Will RG | 2000 | Lancet2000，36，： | 1 |
| 9 | Late complications after open carpal tunnel decompression显示文摘 | Kluge W Simpson RG Nicol AC | 1996 | J Hand Surg Br1996，21，20： | 1 |
| 10 | Dehydration and cognitive performance 显示文摘 | Ann CG Nicole RG | 2007 | J Am Coil Nutr2007，26，： | 1 |
| 11 | Pollen consumption in honey bee larvae: a step forward in the risk assessment of transgenic plants显示文摘 | DIRK B NICOLE K JRG R | 2004 | Apidologie2004，35，： | 1 |
| 12 | Local Anesthetics and Mode of Delivery:Bupivacaine Versus Ropivacaine Versus Levobupivacaine 显示文摘 | Yaakov B Nicole RG Howard HB | 2007 | Anesth Analg2007，105，3： | 1 |
| 13 | Thresholding of statistical maps in functional neuroimaging using the false discovery rate显示文摘 | Nicole AL Thomas N | 2002 | Neuroimage2002，15，： | 1 |
| 14 | W/O microemulsions forocular delivery:Evaluation of ocular irritation andprecorneal retention显示文摘 | Alany RG Rades T Nicoll J | 2006 | Journal of Controlled Release2006，11，1： | 1 |
| 15 | 沙特阿拉伯法赫德国王国家图书馆显示文摘沙特阿拉伯法赫德国王国家图书馆是沙特阿拉伯重要的文化建筑之一。EckhardGerber教授和他的设计团队在沙特阿拉伯的首都利雅得完成了该项重要设计,全新的建筑很好地诠释出当代阿拉伯城市的发展与文化,此项设计起到促进城市发展的推动作用。 | Eckhard Gerber Thomas L1ckin Britta Alker Olaf Ballerstedt Carolin Balkenhok Hans Christoph Bittner Markus Grtz Juana Grunwald Thomas Helms Nicole Juchems Alexandra Kranert Ren Koblank Nils Kummer Stefan Lemke Jrg Schneweis Van Hai Nguyen EckhardGerber Gerber Architekten Kienle Planungsgesellschaft 姜敏华 | 2014 | 现代装饰2014，，3： | 0 |
| 16 | Prevalence of fever of unidentifed aetiology in East African adolescents and adults: a systematic review and meta-analysis显示文摘Background Primary health care settings and hospitals of low-and middle-income countries have few accessible diagnostic tools and limited laboratory and human resources capacity to identify multiple pathogens with high accu‑racy.In addition,there is a paucity of information on fever and its underlying aetiology in the adolescent and adult population in East Africa.The purpose of this study was to estimate the pooled prevalence of fever of unidentifed aetiology among adolescent and adult febrile patients seeking health care in East Africa.Methods We pursued a systematic review using readily available electronic databases(i.e.PubMed,Cumulative Index to Nursing&Allied Health Literature,Scopus,Cochrane Library and Web of Science)without language restric‑tion from inception date of the respective databases to October 31,2022.We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.Identifed studies were screened for relevance.Further analyses based on pre-set eligibility criteria were carried out for fnal inclusion.Two reviewers independently screened and extracted data.Risk of study bias was assessed.Meta-analysis of the prevalence of fever of unidentifed aetiology was performed.Results We identifed 14,029 articles of which 25 were eligible for inclusion,reporting data from 8538 participants.The pooled prevalence of febrile cases with unidentifed aetiology was 64%[95%confdence interval(CI):51–77%,I 2=99.6%]among febrile adolescents and adults in East Africa.For the proportion of patients with identifed aetiol‑ogy,the studies documented bacterial pathogens(human bloodstream infections),bacterial zoonotic pathogens and arboviruses as the main non-malarial causative agents in East Africa.Conclusions Our study provides evidence that almost two-thirds of adolescent and adult febrile patients attending health care facilities in East Africa might receive inappropriate treatments due to unidentifed potential life-threat‑ening fever aetiology.Hence,we call for a comprehensive fever syndromic surveillance to broaden a consequential diferential diagnosis of syndromic fever and to considerably improve the course of patients’disease and treatment outcomes. | Faisal Nooh Afona Chernet Klaus Reither James Okuma Norbert W.Brattig Jürg Utzinger Nicole Probst-Hensch Daniel H.Paris Anou Dreyfus | 2023 | Infectious Diseases of Poverty2023，12，3： | 0 |
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