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221篇 您的检索式:作者名="Niizuma"
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1tRNA cleavage: a new insight显示文摘Over the past decades,tRNA was found to be a rich hub of RNA modifications such as 1-methyladenosine and 5-methycytosine modifications and others,holding more than half of all modifications occurring in RNA molecules.Moreover,tRNA was discovered to be a source of various small noncoding RNA species,such as the stress induced angiogenin cleaved tRNA halves(tiRNA)or the miRNA like tRNA derived fragments.tRNA cleavage under stress was fist discovered in bacteria and later was found to be conserved across different species,including mammals.Under cellular stress conditions,tRNA undergoes conformational changes and angiogenin cleaves it into 3′and 5′halves.5′tiRNA halves were shown to repress protein translations.tRNA cleavage is thought of to be a cytoprotective mechanism by which cells evade apoptosis,however some data hints to the opposite;that tiRNA are cytotoxic or at least related to apoptosis initiation.tRNA cleavage also was shown to be affected by tRNA modifications via different enzymes in the cytosol and mitochondria.In this review,we will highlight the biology of tRNA cleavage,show the evidence of it being cytoprotective or a marker of cell death and shed a light on its role in disease models and human diseases as well as possible future directions in this field of RNA research.Sherif Rashad Kuniyasu Niizuma Teiji Tominaga 2020Neural Regeneration Research2020,15,1:5
2Impact of left ventricu- lar end - diastolic wall stress on plasma B - type natriuretic pep- tide in heart failure with chronic kidney disease and end - stage renal disease显示文摘Niizuma S lwanaga Y Yabata T 2009Clinical Chemistry2009,55,7:1
3Minocycline prevents focal neurological deterioration due to cerebral hyperperfusion after extracranial-intracranial bypass for moyamoya disease 显示文摘Fujimura M Niizuma K Inane T 2014Neurosurgery2014,74,17:1
4Efficacy of low-density lipoprotein apheresis in arteriosclerosis obliterans of the lower extremities: two cases with marked alleviation of clinical symptoms显示文摘Suzuki T Sato Y Niizuma S 2007J Clin Apher2007,22,:1
5Stereotactic aspiration of putaminal hemorrhage using a double track aspiration technique显示文摘Niizuma H Suzuki J 1998Neurosurgery1998,22,5:1
6Middle cerebral artery plaque imaging using 3-Tesla high-resolution MRI显示文摘Niizuma K Shimizu H Takada S 0,,10:1
7NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia 显示文摘YOSHIOKA H NIIZUMA K KATSU M 2011J Cereb Blood Flow Metab2011,31,3:1
8Neural stem cells genetically modified to overexpress cu/zn-superoxide dis- mutase enhance amelioration of ischemic stroke in mice 显示文摘Sakata H Niizuma K Wakai T 2012Stroke2012,43,9:1
9Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival显示文摘Niizuma K Endo H Chan PH 2009J Neurochem2009,109,1:1
10blitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia显示文摘Niizuma K Yoshioka H Chen H 2010Bioehim Biophys Acta2010,1802,1:1
11Oxidative Stress and Mitochondrial Dysfunction as Determinants of Ischemic Neuronal Death and Survival 显示文摘Niizuma KUNIYASU Endo HIDENORI Chan Pak H 2009Journal of Neurochemistry2009,109,1:1
12Stereotactic aspiration of putaminal hemorrhage using a double track sapiration technique 显示文摘Niizuma H Suauki J 1988Neurosurgery1988,22,:1
13Efficacy of revascularization surgery for moyamoya syndrome associated with Graves' disease显示文摘Endo H Fujimura M Niizuma K 2010Nem Med Chit (Tokyo)2010,50,:1
14Cooling the cornea to prevent side effects of photorefractive keratectomy显示文摘Niizuma T Ito S Hayashi M 1994J Refract Corneal Surg1994,10,2:1
15Mitochondrial and apoptotic neumnal death signaling pathways in cerebral ischemia显示文摘Niizuma K Yoshioks H Chen H 2010Biochim Biophy Acta2010,1802,1:1
16Potential role of PUMA in de- layed death of hippocampal CA1 neurons after transient global cerebral ischemia显示文摘Niizuma K Endo H Nito C 2009Stroke2009,40,2:1
17Plasma B-type natriure- tic Peptide levels reflect the presence and severity of stable coronary artery disease in chronic haemodialysis patients 显示文摘Niizuma S I wanaga Y Yalata T 2009NDP2009,24,2:1
18Concurrent dural and perimedullary arteriovenous fistulas at the craniocervical junction: case series with special reference to angioarchi- tecture 显示文摘Sato K Endo T Niizuma K 2013J Neurosurg2013,118,2:1
19Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia 显示文摘Niizuma K Yoshioka H Chen H 2010Biochim Biophys Acta2010,1802,1:1
20Stereotactic aspiration of putaminal hemorrhage using a double track aspiration technique显示文摘Niizuma H Suauki J 0,,02:1
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