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| 1 | Comparative clinical study of ultrasound-guided A1 pulley release vs open surgical intervention in the treatment of trigger finger显示文摘AIM To investigate the effectiveness of ultrasound-guided release of the first annular pulley and compare results with the conventional open operative technique.METHODS In this prospective randomized, single-center, clinical study, 32 patients with trigger finger or trigger thumb, grade Ⅱ-Ⅳ according to Green classification system, were recruited. Two groups were formed; Group A(16 patients) was treated with an ultrasound-guided percutaneous release of the affected A1 pulley under local anesthesia. Group B(16 patients) underwent an open surgical release of the A1 pul ey, through a 10-15 mm incision. Patients were assessed pre- and postoperatively(follow-up:2,4 and 12 wk) by physicians blinded to the procedures. Treatment of triggering(primary variable of interest) was expressed as the 'success rate' per digit. The time for taking postoperative pain killers, range of motion recovery, QuickD ASH test scores(Greek version), return to normal activities(including work), complications and cosmetic results were assessed.RESULTS The success rate in group A was 93.75%(15/16) and in group B 100%(16/16). Mean times in group A patients were 3.5 d for taking pain killers, 4.1 d for returning to normal activities, and 7.2 and 3.9 d for complete extension and flexion recovery, respectively. Mean Quick DASH scores in group A were 45.5 preoperatively and, 7.5, 0.5 and 0 after 2, 4, and 12 wk postoperatively. Mean times in group B patients were 2.9 d for taking pain killers, 17.8 d for returning to normal activities, and 5.6 and 3 d for complete extension and flexion recovery. Mean QuickD ASH scores in group B were 43.2 preoperatively and, 8.2, 1.3 and 0 after 2, 4, and 12 wk postoperatively. The cosmetic results found excellent or good in 87.5%(14/16) of group A patients, while in 56.25%(9/16) of group B patients were evaluated as fair or poor.CONCLUSION Treatment of the trigger finger using ultrasonography resulted in fewer absence of work days, and better cosmetic results, in comparison with the open surgery technique. It is a promising method that represents excellent results without major complications, so that it could be possibly be established as a first-line treatment in the trigger finger's disease. | Vasileios S Nikolaou Michael-Alexander Malahias Maria-Kyriaki Kaseta Ioannis Sourlas George C Babis | 2017 | World Journal of Orthopedics2017，8，2： | 14 |
| 2 | Common controversies in total knee replacement surgery: Current evidence显示文摘Total knee replacement(TKR) is a widely used operation that has radically improved the quality of life of millions of people during the last few decades. However, some technical details, concerning the surgical procedure and the rehabilitation following total knee arthroplasty, are still a matter of a strong debate. In this review of the literature, we have included the best evidence available of the last decade, in an effort to shed light on some of the most controversial subjects related to TKR surgery. Posterior-stabilized or cruciate-retaining prosthesis? To use a tourniquet during operation or not? Do patients need continuous passive motion for their post-surgery rehabilitation? To resurface patella or not? These are some of the most controversial topics that until now have been persistent dilemmas for the orthopedic surgeon. Results of this systematic review of the literature are highly controversial. These conflicting results are an indication that larger and more well conducted high quality trials are needed in order to gain more secure answers. At the same time, it is becoming apparent that a meticulous operative technique, respecting the soft tissue envelope and knowing the principles of alignment and soft tissue balancing, aresome of the parameters that might contribute more to achieving the optimal results for the patients. | Vasileios S Nikolaou Dimitrios Chytas George C Babis | 2014 | World Journal of Orthopedics2014，5，4： | 9 |
| 3 | It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis显示文摘Background There is concern that blood pressure(BP)lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis.We assessed the effect of glyceryl trinitrate(GTN)in patients with carotid stenosis using data from the Efficacy of Nitric Oxide in Stroke(ENOS)Trial.Methods ENOS randomised 4011 patients with acute stroke and raised systolic BP(140-220 mm Hg)to transdermal GTN or no GTN within 48 hours of onset.Those on prestroke antihypertensives were also randomised to stop or continue their medication for 7 days.The primary outcome was the modified Rankin Scale(mRS)at day 90.Ipsilateral carotid stenosis was split:<30%;30-<50%;50-<70%;≥70%.Data are ORs with 95%CIs adjusted for baseline prognostic factors.results 2023(60.5%)ischaemic stroke participants had carotid imaging.As compared with<30%,≥70%ipsilateral stenosis was associated with an unfavourable shift in mRS(worse outcome)at 90 days(OR 1.88,95%CI 1.44 to 2.44,p<0.001).Those with≥70%stenosis who received GTN versus no GTN had a favourable shift in mRS(OR 0.56,95%CI 0.34 to 0.93,p=0.024).In those with 50-<70%stenosis,continuing versus stopping prestroke antihypertensives was associated with worse disability,mood,quality of life and cognition at 90 days.Clinical outcomes did not differ across bilateral stenosis groups.Conclusions Following ischaemic stroke,severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days.GTN appears safe in ipsilateral or bilateral carotid stenosis,and might improve outcome in severe ipsilateral carotid stenosis. | Jason P Appleton Lisa J Woodhouse Andrew Belcher Daniel Bereczki Eivind Berge Valeria Caso Hui Meng Chang Hanne K Christensen Ronan Collins John Gommans Ann C Laska George Ntaios Serefnur Ozturk Gillian M Sare Szabolcs Szatmari Yongjun Wang Joanna M Wardlaw Nikola Sprigg Philip M Bath for the ENOS investigators | 2019 | Stroke & Vascular Neurology2019，4，1： | 6 |
| 4 | Successful endoscopic treatment of an intraductal papillary neoplasm of the bile duct显示文摘We present a case of a 76-year-old man with right upper quadrant abdominal pain and weight loss,who was found to have an intraductal papillary neoplasm of the bile duct(IPNB)of the pancreaticobiliary subtype,deemed curatively resectable.The patient declined surgery and opted for endoscopic therapy.He underwent two sessions of endoscopic retrograde cholangiopancreatography(ERCP)-guided radiofrequency ablation(RFA).Ten months later,no evidence of recurrence was identified on repeat ERCP.To our knowledge,this is the first reported case of successful use of RFA as a primary treatment modality for resectable IPNB. | Nikola S Natov Laura C Horton Sanjay R Hegde | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，5： | 5 |
| 5 | Accuracy of 64-MDCT in the diagnosis of isehemic heart disease 显示文摘 | Nikolaou K Knez A Rist C | 2006 | AJR2006，187，1： | 1 |
| 6 | Comparison of carotid stents: an in-vitro experiment focusing on stent design 显示文摘 | Stefan MH Philipp JS Nikolas C | 2009 | J Endovasc Ther2009，16，2： | 1 |
| 7 | Comparison of carotidstents: an In-vitro Experiment focusing on stent design显示文摘 | Stefan MH Philipp JS Nikolas C | 2009 | J Endo-vasc Ther2009，16，2： | 1 |
| 8 | Antimicrobial and eytotoxic activities of Oreganum essential oils 显示文摘 | Sivropoulou A Paranikolaou E Nikolaou C | 1996 | Agric Food Chem1996，44，： | 1 |
| 9 | Pre-and postsurgical diagnostics with dual-source computed tomography in cardiac surgery 显示文摘 | Nikolaou K Saam T Rist C | 2007 | Radiologe2007，47，4： | 1 |
| 10 | Minimally invasive plate osteosynthesis - an update 显示文摘 | Nikolaou VS Efstathopoulos N Papakostidis C | 2008 | Curr Orthop2008，22，3： | 1 |
| 11 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (alliurn sativum) 显示文摘 | Athanasios C Nikolas G S Dimitra J D | 2006 | Ultrasonics Sonochemistry2006，13，1： | 1 |
| 12 | Accuracy of 64-MDCT in the diagnosis of ischemic heart disease显示文摘 | Nikolaou K Knez A Rist C | 2006 | AJR Am J Roentgenol2006，187，1： | 1 |
| 13 | Clinical value of MDCT in the diagnosis of coronary artery disease in patients with a low pretest likelihood of significant disease 显示文摘 | Nikolaou K Rist C Wintersperger BJ | 2006 | A JR Am J Roentgenol2006，186，6： | 1 |
| 14 | Accuracy of 64-MDCT in the diagnosis of ischemic heart disease显示文摘 | Nikolaou K Knez A Rist C | | 0，，： | 1 |
| 15 | Accuracy of 64-MDCT in the diagnosis of ischemic heart disease显示文摘 | Nikolaou K Knez A Rist C | 2006 | AJR Am J Ro- entgenol2006，187，1： | 1 |
| 16 | Serum uric acid levels in patients with Parkinson's disease: their relationship to treatment and disease duration 显示文摘 | Andreadou E Nikolaou C Goumaras F | 2009 | Clin Neurol Neurosurg2009，111，9： | 1 |
| 17 | Brain natriuretic peptide increases in septic patients without severe sepsis or shock显示文摘 | Nikolaou NI Goritsas C Dede M | 2007 | Eur J Intern Med2007，18，7： | 1 |
| 18 | A fast space - vector modulation algorithm for multilevel three - phase converters 显示文摘 | NIKOLA C DASHAN B | 2001 | IEEE Transactions on Industry Applications2001，37，2： | 1 |
| 19 | In- terteukin-17 and interleukin-23 are elevated in serumand cerebrospinal fluid of patients with ALS; a reflec- tion of Th17 cells activation? 显示文摘 | RENTZOS M ROMBOS A NIKOLAOU C | 2010 | Acta Neurol Scand2010，3，： | 1 |
| 20 | Innovative prestressing with FRP sheets:Mechanics of short-term behavior显示文摘 | Thanasis C Triantafillou Nikola Deskovic | 1991 | Journal of Engineering Mechanics1991，117，7： | 1 |
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