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292篇 您的检索式：作者名="Nilius"

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	题名	作者	年代	出处	被引量
1	TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘	Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu	2012	Cell Research2012，22，3：	18
2	Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity显示文摘Brown adipose tissue(BAT)is an energy-expending organ that produces heat.Expansion or activation of BAT prevents obesity and diabetes.Chronic cold exposure enhances thermogenesis in BAT through uncoupling protein 1(UCP1)activation triggered via a b-adrenergic pathway.Here,we report that the cold-sensing transient receptor potential melastatin 8(TRPM8)is functionally present in mouse BAT.Challenging brown adipocytes with menthol,a TRPM8 agonist,up-regulates UCP1 expression and requires protein kinase A activation.Upon mimicking long-term cold exposure with chronic dietary menthol application,menthol significantly increased the core temperatures and locomotor activity in wild-type mice;these effects were absent in both TRPM82/2 and UCP12/2 mice.Dietary obesity and glucose abnormalities were also prevented by menthol treatment.Our results reveal a previously unrecognized role for TRPM8,suggesting that stimulation of this channel mediates BAT thermogenesis,which could constitute a promising way to treat obesity.	Shuangtao Ma Hao Yu Zhigang Zhao Zhidan Luo Jing Chen Yinxing Ni Rongbing Jin Liqun Ma Peijian Wang Zhenyu Zhu Li Li Jian Zhong Daoyan Liu Bernd Nilius Zhiming Zhu	2012	Journal of Molecular Cell Biology2012，4，2：	2
3	Amazing chloride channels: an overview显示文摘	Nilius B Droogmans G	2003	Acta Physiol Scand2003，177，：	1
4	Voltage dependence of the Ca2+- activated cation channel TRPM4显示文摘	Nilius B Prenen J Droogmans G	2003	J Biol Chem2003，278，30：	1
5	80K H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel TRPV5 显示文摘	Gkika D Mahieu F Nilius B	2004	J Biol Chem2004，279，26：	1
6	Pressure-relief continuous positive airway pressure vs constant continuous positive airway pressure:a comparison of efficacy and compliance显示文摘	Georg Nilius Andreas Happel Ulrike Domanski	2006	Chest2006，130，：	1
7	TRPV4 calcium entry channel:a paradigm for gating diversity 显示文摘	Nilius B Vriens J Prenen J	2004	Am J Physiol Cell Physiol2004，286，2：	1
8	Ketolides:the future of the macrolides? 显示文摘	Nilius A M Ma Z	2002	Curr Opin Pharmacol2002，2，5：	1
9	Regulation of the mouse epithelial Ca2+ channel TRPV6 by the Ca2+ -sensor calmodulin 显示文摘	Lambers TT Weidema AF Nilius B	2004	J Biol Chem2004，279，28：	1
10	Effects of nasal insufflation on arterial gas exchange and breathing pattern in patients with chronic obstructive pulmonary disease and hypercapnic respiratory failure 显示文摘	Nilius G Franke K J Domanski U	2013	Adv Exp Med Biol2013，755，：	1
11	Trp channels in disease 显示文摘	Nilius B	2007	Biochimica et bio- physica acta2007，1772，：	1
12	Whole-cell and single channel monovalent cation currents through the novel rabbit epithelial Ca2+channel显示文摘	Nilius B Vennekens R Prenen J	2000	J Physiol2000，527，2：	1
13	Biophysics and structure-function relationship of T-type Ca^2+ channels 显示文摘	Talavera K Nilius B	2006	Cell Calcium2006，40，：	1
14	Vanilloid transient receptor potential cation channels:an overview显示文摘	Vennekens R Owsianik G Nilius B	2008	Curr Pharm Des2008，14，1：	1
15	Regula- tion of the mouse epithelial Ca^2+ channel TRPV6 by the Ca^2+-sensor ealmodulin 显示文摘	Lambers T T Weidema A F Nilius B	2004	Biol Chem2004，279，28：	1
16	Helicobacter pylori-mediated gastritis induces local downregulation of secretory leukocyte protease inhibitor in the antrum显示文摘	Wex T Treiber G Nilius M	2004	Infect Immun2004，72，4：	1
17	Ion channels and their functional role in vascular endothelium 显示文摘	Nilius B Droogmans G	2001	Physiol Rev2001，81，：	1
18	The TRPV4 channel : structure-func- tion relationship and promiscuous gating behavior显示文摘	Nilius B Watanabe H Vriens J	2003	Pflugers Arch2003，446，3：	1
19	TRP channels: a TR( I )P through a world of muhifunctional cation channels 显示文摘	Nilius B Voets T	2005	Pflugers Arch2005，451，1：	1
20	Transient receptor potential cation channels in disease 显示文摘	Nilius B Owsianik G Voets T	2007	Physiol Rev2007，87，：	1

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