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10篇 您的检索式：作者名="Niogret"

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		题名	作者	年代	出处	被引量
	1	Effect of 20-hydroxyecdysone on cannibalism, sexual behavior, and contact sex pheromone in the solitary female spider, Tegenaria atrica 显示文摘	Trabalon M Niogret J Legrand-Frossi C	2005	General and comparative Endocrinology2005，144，1：	1
	2	Characterization of pollen polygalacturonase encoded by several cDNA clones in maize显示文摘	Niogret M F Dubald M Mandaron P	1991	Plant Molecular Biology1991，17，：	1
	3	Metabolome and water homeostasis analysis of Thellungiella salsuginea suggests that dehydration tolerance is a key response to osmotic stress in this halophyte显示文摘	Lugan R Niogret MF Leport L		0，，02：	1
	4	Metabolome and water homeostasis analysis of TheUungiella salsuginea suggests that dehydration tolerance is a key response to osmotic stress in this halophyte 显示文摘	Lugan R Niogret MF Leport L	2010	The Plant Journal2010，64，2：	1
	5	EGFR amplification induces sensitivity to antiEGFR therapy in pancreatic acinar cell carcinoma显示文摘Pancreatic acinar cell carcinoma(PACC) is a rare cancer. When the tumor is metastatic, few therapeutic options are available. Precision medicine using next-generation sequencing is defined by the administration of drugs based on the tumor genetic mutations. The usage of precision medicine for finding new therapeutic options for rare cancers is an emerging field. We have reported here the case of a patient bearing a multitreated metastatic PACC. This patient underwent somatic and constitutional exome analyses. The analyses revealed in the liver metastasis an amplification of the EGFR gene. Accordingly, the patient was treated with off-label usage of panitumumab. We observed rapid response with necrosis of the liver metastasis, while no efficacy was observed in the primary tumor. An exome analysis of the primary tumor revealed amplification of HER2 and MET with EGFR amplification. Such amplifications are known as a resistance mechanism to anti EGFR therapy. Our results suggest that exome analysis may be helpful to highlight targets in rare cancers, such as PACC. EGFR amplification in this pathology should be determined and could be used as a biomarker to propose anti EGFR therapy.	Corentin Richard Julie Niogret Romain Boidot Francois Ghiringhelli	2018	World Journal of Gastrointestinal Oncology2018，10，4：	1
	6	Metabolome and water home- ostasis analysis of Thellungiella salsuginea suggests that dehydration tolerance is a key response to osmotic stress in this halophyte 显示文摘	Lugan R Niogret M F Leport L	2010	The Plant Journal2010，64，2：	1
	7	Effects of the in- hibitor of the y-aminobutyrate-transaminase, vinyl-γ- aminobutyrate,on development and nitrogen metabo- lism in Brassica napus seedlings显示文摘	Deleua C Faes P Niogret MF	2013	Plant Physiology and Bio-chemistry2013，64，：	1
	8	Pronline level is partly underthe control of abcisic acid in canola leaf discs during recovery fromhyper - osmotic stress显示文摘	Trotel - Aziz P Niogret M F Larher F	2000	Physiologia Plantarum2000，110，：	1
	9	Characterization of pollen polygalacturonase encoded by several cDNA clones in maize显示文摘	Marie-Fran?oise Niogret Manuel Dubald Paul Mandaron Régis Mache	1991	Plant Molecular Biology1991，，6：	1
	10	Proline level is partly under the control of abscisic acid in canola leaf discs during recovery from hyper-osmotic stress显示文摘	Trotel-Aziz P Niogret MF Larher F	2000	Physiol Plant2000，110，：	1

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