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3篇 您的检索式:作者名="Nisha Patel"
    题名 作者 年代 出处 被引量
1Flexible platforms for natural orifice transluminal and endoluminal surgery显示文摘Nisha Patel Carlo Seneci Guang-Zhong Yang Ara Darzi Julian Teare 2014EIO2014,,:1
2Meta-analysis comparing differing methods of endoscopic therapy for colorectal lesions显示文摘AIM:To compare the outcomes of endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD) of colorectal lesions.METHODS:An electronic systematic literature search of four computerized databases was performed in July 2014 identifying studies reporting the outcomes of colorectal ESD and EMR.The primary outcome measures were en-bloc resection rate,endoscopic clearance rate and lesion recurrence rate of the patients followed up.The secondary outcome was the complication rate(including bleeding,perforation and surgery post EMR or ESD rate).Statistical pooling and random effects modelling of the studies calculating risk difference,heterogeneity and assessment of bias and quality were performed.RESULTS:Six observational studies reporting the outcomes of 1324 procedures were included.The en-bloc resection rate was 50% higher in the ESD group than in the EMR group(95%CI:0.17-0.83,P<0.0001,I2=99.7%).Endoscopic clearance rates were also significantly higher in the ESD group(95%CI:-0.06-0.02,P < 0.0001,I^2=92.5%).The perforation rate was 7% higher in the ESD group than the EMR group(95%CI:0.05-0.09,P>0.05,I^2=41.1%) and the rate of recurrence was 50% higher in the EMR group than in the ESD group(95%CI:0.20-0.79,P<0.001,I^2=99.5%).Heterogeneity remained consistent when subgroup analysis of high quality studies was performed(with the exception of piecemeal resection rate),and overall effect sizes remained unchanged for all outcomes.CONCLUSION:ESD demonstrates higher en-bloc resection rates and lower recurrence rates compared to colorectal EMR.Differences in outcomes may benefit from increased assessment through well-designed comparative studies.Nisha Patel James Alexander Hutan Ashrafian Thanos Athanasiou Ara Darzi Julian Teare 2016World Journal of Meta-Analysis2016,4,2:0
3Orientation in upper gastrointestinal endoscopy—the only way is up显示文摘BACKGROUND Oesophagogastroduodenoscopy is the gold standard investigation for the upper gastrointestinal(UGI)tract.Orientation during endoscopy is challenging and United Kingdom training focusses on technical competence and procedural safety.The reported location of UGI pathologies is crucial to post-endoscopic planning.AIM To evaluate endoscopists’ability to spatially orientate themselves within the UGI tract.METHODS A cross sectional descriptive study elicited,using an anonymised survey,the ability of endoscopists to orientate themselves within the UGI tract.The primary outcome was percentage of correct answers from all surveyed;secondary outcomes were percentage of correct answers from experienced vs novice endoscopists.Pearson’sχ2 test was applied to compare groups.RESULTS Of 188 respondents,86 were experienced endoscopists having completed over 1000 endoscopies.44.4%of respondents correctly identified the anterior stomach and 47.3%correctly identified the posterior of the second part of the duodenum(D2).Experienced endoscopists were significantly more likely than novice to identify the anterior stomach correctly[61.6%vs 31.3%,X2(1,n=188)=11.10,P=0.001].There was no significant difference between the two groups in identifying the posterior of D2.CONCLUSION The majority of endoscopists surveyed were unable to identify key landmarks within the UGI tract.Endoscopic orientation appears to improve with experience yet there are some areas still not well recognised.This has potential considerable impact on post-endoscopic management of patients with posterior duodenal ulcers being more likely to perforate and associated with a higher rebleeding risk.We suggest the development of a consensus statement on endoscopic description.Arun Sivananthan Georgina Kerry Ara Darzi Kinesh Patel Nisha Patel 2023World Journal of Gastrointestinal Endoscopy2023,15,3:0
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