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| 1 | Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting显示文摘AIM: To investigate the outcome of patients with symptoms of gastroesophageal reflux disease (GERD) referred for endoscopy at 2 and 6 mo post endoscopy. METHODS: Consecutive patients referred for upper endoscopy for assessment of GERD symptoms at two large metropolitan hospitals were invited to participate in a 6-mo non-interventional (observational) study.The two institutions are situated in geographically and socially disparate areas. Data collection was by selfcompletion of questionnaires including the patient assessment of upper gastrointestinal disorders symptoms severity and from hospital records. Endoscopic finding using the Los-Angeles classification, symptom severity and it's clinically relevant improvement as change of at least 25%, therapy and socio-demographic factors were assessed. RESULTS: Baseline data were available for 266 patients and 2-mo and 6-mo follow-up data for 128 and 108 patients respectively. At baseline, 128 patients had erosive and 138 non-erosive reflux disease. Allmost all patient had proton pump inhibitor (PPI) therapy in the past. Overall, patients with non-erosive GERD at the index endoscopy had significantly more severe symptoms as compared to patients with erosive or even complicated GERD while there was no difference with regard to medication. After 2 and 6 mo there was a small, but statistically significant improvement in symptom severity (7.02 ± 5.5 vs 5.9 ± 5.4 and 5.5 ± 5.4 respectively); however, the majority of patients continued to have symptoms (i.e. , after 6 mo 81% with GERD symptoms). Advantaged socioeconomic status as well as being unemployed was associated with greater improvement. CONCLUSION: The majority of GORD patients receive PPI therapy before being referred for endoscopy even though many have symptoms that do not sufficiently respond to PPI therapy. | Nora B Zschau Jane M Andrews Richard H Holloway Mark N Schoeman Kylie Lange William CE Tam Gerald J Holtmann | 2013 | World Journal of Gastroenterology2013，19，16： | 2 |
| 2 | Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies显示文摘 | Nora M A P Carlos A P Elsa B D | 2003 | Carbohyd Res2003，338，2： | 1 |
| 3 | Technology and Higher Education:The Impact of E-Learning Approaches on Student Academic Achievement,Perceptions and Persistence显示文摘 | Nora A Snyder B P | | 0，，： | 1 |
| 4 | Study of 17 β-estradiol-5-benzoate, 17 α-methyltestosterone and medroxyprogesterone acetate fixation in bovine hair显示文摘 | LAURIANE R EMMANUELLE B NORA C | 2005 | Anal Chim Acta2005，532，2： | 1 |
| 5 | An Antifungal Tetrapeptide from the culture of Penicillium canescens 显示文摘 | Brenda V B Nora I P Gabriela M C | 2009 | Chem Biod2009，6，8： | 1 |
| 6 | A novel ion monitoring device 显示文摘 | Noras M A Williams B T Kieres J | 2005 | Journal of Electrostatics2005，69，： | 1 |
| 7 | Vaspin gene expression in human adipose tissue:Association with obesity and type 2 diabetes 显示文摘 | NORA K JANIN B SUSAN K | 2006 | Biochemical & Biophysical Research Commurdeations2006，339，1： | 1 |
| 8 | Determinants of c- are giving burden and quality of life in caregivers of stroke pa- tients显示文摘 | Emily McCullagh Gavin B Nora D | 2005 | Stroke2005，36，： | 1 |
| 9 | Cocaine-and amphetamine-regulated transcript (CART) acceler- ates the temination of FSH-induced ERK1/2 and AKT activation by regulating the expression and deg- radation of specific mitogen-activated protein kinase phosphatases in bovine granulosa cells显示文摘 | ARITRO S LV L H NORA B | 2008 | Mol En- docrinol2008，22，12： | 1 |
| 10 | Inhibition of mitochondrial energylinked reaction by 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (dimboa),a hydroxamic acid from gramineae显示文摘 | HERMANN M NIEMEYER NORA B CALATERRA OSCAR A ROVERI | 1986 | Biochemical pharmacology1986，35，22： | 1 |
| 11 | Lal-xCaxCoO3 perovskite-type oxides: preparation, characterisation, stability, and catalyticpotentialitytbr the total oxidation of propane显示文摘 | Nora A M Bibiana P B Grange P | 2005 | Journal of Catalysis2005，231，1： | 1 |
| 12 | Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity 显示文摘 | Matthias B Stefan E Nora K | 2006 | Diabetes2006，55，11： | 1 |
| 13 | Spatial partitioning of the regulatory landscape of the X inactivation center 显示文摘 | Nora E P Lajoie B R Schulz E G | 2013 | Nature2013，485，7398： | 1 |
| 14 | Drug addiction: the neurobiology of disrupted self-control显示文摘 | Ruben D B Nora D V | 2000 | Trends in Molecular Medicine2000，12，12： | 1 |
| 15 | Exploiting the intrinsic hydrocarbon-degrading microbial capacities in oil tank bottom sludge and waste soil for sludge bioremediation显示文摘 | NORA B S PAULINE V G ALETTE A M L | 2015 | International Journal of Environmental Science and Technology2015，12，： | 1 |
| 16 | Modifications of thesympathetic skin response in workers chronically exposed to lead显示文摘 | Nora D B Gomes I Said G | 2007 | Braz J Med Biol Res2007，40，1： | 1 |
| 17 | Success of Clinical Pathways for Total Joint Arthroplasty in a Community Hospital 显示文摘 | Frank W Nora B | 2006 | Clinical Orthopae- dics2006，457，12： | 1 |
| 18 | Reporting structural equation modeling and confirmatory factor analysis results: A review显示文摘 | Schreiber J B Nora A Stage F K | 2006 | The Journal of educational research2006，99，6： | 1 |
| 19 | Radiofrequency ablation in 447 complex unresectable liver tumors:lessons leaned 显示文摘 | B leicher RJ A llegra DP Nora DT | 2003 | Ann Surg Oncol2003，10，： | 1 |
| 20 | Glycobiology of neuroblastoma: impaet on tumor behavior, prognosis, and therapeutic strategies显示文摘 | Nora B Eduardo O | 2014 | Front On- col2014，4，： | 1 |
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