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| 1 | Status of the Specialty of Physical and Rehabilitation Medicine显示文摘The objectives of this paper are to help specialists in Physical and Rehabilitation Medicine plan their careers, influence the future of the PRM specialty and advocate effectively for those with limitations of functioning. The experiences of the authors are the sources of its observations and suggestions. The senior author has had extensive national and international experience in the specialty as a clinician, teacher, researcher, manager, leader and advocate. The junior author adds the insights of one who only recently has become immersed in PRM. The following are suggestions and observations the authors believe could contribute to the future success of individual PRM specialists and the PRM specialty. ①Review and reinforce the significant accomplishments of PRM over the last 70 years. It has significantly expanded the focus of health care to include the importance of functioning. ②Identify the specialty′s current strengths, weaknesses, threats and opportunities. As a clinical specialty, it has expanded nationally and internationally, yet its research contributions remain limited. The absence of an evidence base for much of its activity risks reduced support from payers, yet the population needing its services continues to expand. ③Develop strategies to increase the ability of PRM specialists and PRM to improve the lives of people with or likely to have limitations of functioning. These strategies could include sharing best practices, supporting effectiveness research and developing expert consensus guidelines. The need for physicians who are experts in the strategies of improving the lives of those with complex problems of functioning will continue to expand. This need will assure the continuation of the specialty of PRM as long as it improves the abilities of its members to help those with problems of functioning, and it advocates for those whom its members serve. | John L . Melvin, MD MMSc John W. Norbury, MD | 2010 | 中国康复医学杂志2010，25，9： | 2 |
| 2 | Constitutive mac ropinocytosis allows TAP-dependent major histocompatibility com plex class I presentation of exogenous soluble antigen by bone mar row-derived dendritic cell显示文摘 | Chambers BJ Prescott AR | 1997 | Eur J Immunol1997，27，1： | 1 |
| 3 | Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumor growth显示文摘 | Oehler MK Norbury C Hague S | 2001 | Oncogene2001，20，23： | 1 |
| 4 | Distinct genetic influences on grammar and phonological short-term memory deficits:evidence from 6-year-old twins显示文摘 | Bishop D.V.M Adams C.V Norbury C.F | | 0，，02： | 1 |
| 5 | Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth显示文摘 | Oehler MK Norbury C Hague S | 2001 | Oncogene2001，20，23： | 1 |
| 6 | The novel murine calmodulin-binding protein Shal disrupts mitotic spindle and replication checkpoint functions in fission yeast显示文摘 | Craig R Norbury C | 1998 | J Cell Sci1998，111，： | 1 |
| 7 | The long and short of microRNA 显示文摘 | Yates LA Norbury C J Gilbert RJ | 2013 | Cell2013，153，3： | 1 |
| 8 | DNA damage-induced apoptosis显示文摘 | Norbury CJ Zhivotovsky B | 2004 | Oncogene2004，23，16： | 1 |
| 9 | Noninvasive prenatal diagnosis of early onset primary dystonia I in maternal plasma 显示文摘 | Meaney C Norbury G | 2009 | Prenat Diagn2009，29，13： | 1 |
| 10 | Comparativeanalysis of global gene expression profiles between diabet-ic rat wounds treated with vaccuum assisted closure ther-apy moist wound healing or gauze under suction 显示文摘 | Derrick KL Norbury K Kieswetter K | 2008 | IntWound J2008，5，5： | 1 |
| 11 | Heavy ion contributions to organ dose equivalent for the 1977 galactic cosmic ray spectrum显示文摘 | Steven A. Walker Lawrence W. Townsend John W. Norbury | 2013 | Advances in Space Research2013，，： | 1 |
| 12 | The long and short of mieroRNA 显示文摘 | Yates LA Norbury C J Gilbert RJ | 2013 | Ce112013，153，3： | 1 |
| 13 | Epidemiology of muhimorbidity and implications for health care research and medical education 显示文摘 | Barnett K Mercer SW Norbury M | 2012 | Lancet2012，380，： | 1 |
| 14 | DNA damage induced apoptosis显示文摘 | Norbury C J Zhivotovsky B | 2004 | Oncogene2004，23，16： | 1 |
| 15 | Cellular responses to DNA damage:cellcycle check points, apoptosis and the roles of p53 and ATM显示文摘 | Enoch T Norbury C | 1995 | Trends Biochem Sci1995，20，10： | 1 |
| 16 | Cellular resoneses to DNA damage:Cell-cycle check points apotosis and the roles of p53 and Atm显示文摘 | Enoch T Norbury C | 1995 | Trends Biochern Sci1995，20，： | 1 |
| 17 | Animal cell eyries and their control 显示文摘 | Norbury C Nurse P | 1992 | Annu Rev Biochem1992，61，： | 1 |
| 18 | Estrogen therapy and brain muscarinic receptor density in healthy females:A SPET study显示文摘 | Norbury R Travis M J Erlandsson K | 2007 | Horm Behav2007，51，2： | 1 |
| 19 | Elevated cortical glutamate in young people at increased famil ial risk of depression 显示文摘 | Matthew J Taylor Zola N Mannie Ray Norbury | 2011 | International Journal of Neuropsy chophacology2011，14，： | 1 |
| 20 | Elevated cortical glutamate in young people at increased familial risk of depression显示文摘 | Taylor M J Mannie ZN Norbury R | | 0，，： | 1 |
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