|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Different strategies of treatment for uterine cervical carcinoma stage ⅠB2-ⅡB显示文摘Uterine cervical cancer is the second most common gynecological malignancy. It is estimated that over 35% of tumors are diagnosed at locally advanced disease, stage ⅠB2-ⅡB with an estimated 5-year overall survival of 60%. During the last decades, the initial treatment for these women has been debated and largely varies through different countries. Thus, radical concurrent chemoradiation is the standard of care in United Sated and Canada, and neoadjuvant chemotherapy followed by radical surgery is the first line of treatment in some institutions of Europe, Asia and Latin America. Until today, there is no evidence of which strategy is better over the other. This article describe the evidence as well as the advantages and disadvantages of the main strategies of treatment for women affected by uterine cervical cancer stage ⅠB2-ⅡB. | Lucas Minig María Guadalupe Patrono Nuria Romero Juan Francisco Rodríguez Moreno Jesús Garcia-Donas | 2014 | World Journal of Clinical Oncology2014，5，2： | 46 |
| 2 | BCL-XL regulates TNF-α-mediated cell death independently of NF-κB, FLIP and IAPs显示文摘 | Raffaella Gozzelino Carme Sole Nuria Llecha Miguel F Segura Rana S Moubarak Victoria Iglesias-Guimarais M Jose Perez-Garcia Stephanie Reix Jisheng Zhang Nahuai Badiola Daniel Sanchis Jose Rodriguez-Alvarez Ramon Trullas Victor J Yuste Joan X Comella | 2008 | Cell Research2008，18，10： | 4 |
| 3 | On-chip wireless silicon photonics: from reconfigurable interconnects to lab-on-chip devices显示文摘Photonic integrated circuits are developing as key enabling components for high-performance computing and advanced networkon-chip,as well as other emerging technologies such as lab-on-chip sensors,with relevant applications in areas from medicine and biotechnology to aerospace.These demanding applications will require novel features,such as dynamically reconfigurable light pathways,obtained by properly harnessing on-chip optical radiation.In this paper,we introduce a broadband,high directivity(4150),low loss and reconfigurable silicon photonics nanoantenna that fully enables on-chip radiation control.We propose the use of these nanoantennas as versatile building blocks to develop wireless(unguided)silicon photonic devices,which considerably enhance the range of achievable integrated photonic functionalities.As examples of applications,we demonstrate 160 Gbit s−1 data transmission over mm-scale wireless interconnects,a compact low-crosstalk 12-port crossing and electrically reconfigurable pathways via optical beam steering.Moreover,the realization of a flow micro-cytometer for particle characterization demonstrates the smart system integration potential of our approach as lab-on-chip devices. | Carlos García-Meca Sergio Lechago Antoine Brimont Amadeu Griol Sara Mas Luis Sánchez Laurent Bellieres Nuria S Losilla Javier Martí | 2017 | Light(Science & Applications)2017，6，1： | 3 |
| 4 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 5 | Circulating levels of GDF15, MMP7 and miR-200c as a poor prognostic signature in gastric cancer显示文摘 | Moisé s Blanco-Calvo Nuria Tarrí o Margarita Reboredo Mar Haz-Conde Jorge Garcí a Marí a Quindó s Angé lica Figueroa Luis Antó n-Aparicio Lourdes Calvo Manuel Valladares-Ayerbes | 2014 | Future Oncol2014，，7： | 2 |
| 6 | Model for end-stage liver disease-Na score or Maddrey discrimination function index, which score is best?显示文摘AIM: To compare the ability of model for end-stage liver disease(MELD)-Na and Maddrey discrimination function index(DFI) to predict mortality at 30 and 90 d in patients with alcoholic hepatitis(AH).METHODS: We prospectively assessed 52 patients with AH. Demographic, clinical and laboratory parameters were obtained. MELD-Na and Maddrey DFI were calculated on admission. Short-term mortality was assessed at 30 and 90 d. Receiver operating characteristic curve analysis was performed. RESULTS: Thirty-day and 90-d mortality was 44% and 58%, respectively. In the univariate analysis, sodium levels was associated with mortality at 30 and 90 d(P = 0.001 and P = 0.03). Child stage, encephalopathy, ascites, or types of treatment were not associated with mortality. MELD-Na was the only predictive factor for mortality at 90 d. For 30-d mortality area under the curve(AUC) was 0.763(95%CI: 0.63-0.89) for Maddrey DFI and 0.784 for MELD-Na(95%CI: 0.65-0.91, P = 0.82). For 90-d mortality AUC was 0.685(95%CI: 0.54-0.83) for Maddrey DFI and 0.8710 for MELD-Na(95%CI: 0.76-0.97, P = 0.041). CONCLUSION: AH is associated with high shortterm mortality. Our results show that MELD-Na is a more valuable model than DFI to predict short-term mortality. | Mercedes Amieva-Balmori Scherezada María Isabel Mejia-Loza Roberto Ramos-González Felipe Zamarripa-Dorsey Eli García-Ruiz Nuria Pérez y López Eumir I Juárez-Valdés Adriana López-Luria José María Remes-Troche | 2015 | World Journal of Hepatology2015，7，17： | 2 |
| 7 | Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration显示文摘The retina may suffer neurodegenerative damages,as other tissues of the central nervous system do,and serious eye diseases may develop.One of them is age-related macular degeneration,which causes progressive loss of vision due to retina degeneration.Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds,among others,that prevent/diminish oxidative stress and reduce neovascularisation respectively.The phytochemicals,medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties.This review article presents the most investigated plants and natural products in relation to age-related macular degeneration,such as saffron,ginkgo,bilberry and blueberry,curcuma or turmeric,carotenoids,polyphenols,and vitamins C and E.This study provides up-to-date information on the effects,treatments,safety and efficiency of these phytotherapy products. | Francisco Bosch-Morell Victoria Villagrasa Teresa Ortega Nuria Acero Dolores Muñoz-Mingarro MEugenia González-Rosende Encarna Castillo MAmparo Sanahuja Pilar Soriano Isabel Martínez-Solís | 2020 | Neural Regeneration Research2020，15，12： | 2 |
| 8 | Maintenance treatment with Pegylated liposomal doxorubicin versus observation following induction chemotherapy for metastatic breast cancer: GEICAM 2001-01 study显示文摘 | Emilio Alba Manuel Ruiz-Borrego Mireia Margelí álvaro Rodríguez-Lescure Pedro Sánchez-Rovira Amparo Ruiz Jose Ramón Mel-Lorenzo Manuel Ramos-Vázquez Nuria Ribelles Elisa Calvo Antonio Casado Antonia Márquez David Vicente José Angel García-Sáenz Miguel Mar | 2010 | Breast Cancer Research and Treatment2010，，1： | 2 |
| 9 | Sticky information and heterogeneous needs as determining factors of R&D coo- peration with customers显示文摘 | Gloria S Nuria G Mariano N | 2009 | Research Policy2009，38，10： | 1 |
| 10 | Are quality and innovation management conflicting activities?显示文摘 | Nuria López-Mielgo José M. Montes-Peón Camilo J. Vázquez-Ordás | 2009 | Technovation2009，，8： | 1 |
| 11 | Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation显示文摘 | Ana Maria Sánchez Sophie Malagarie-Cazenave Nuria Olea Diana Vara Antonio Chiloeches Inés Díaz-Laviada | 2007 | Apoptosis2007，，11： | 1 |
| 12 | Protein S secretion difference of missence mutants account for phenotypic hetergenity 显示文摘 | Yolanda EP Tomio Y Nuria S | 2000 | Blood2000，95，3： | 1 |
| 13 | Synthesis and characterization of carbon nanotube-conducting polymer thin films 显示文摘 | Martti K Viera S | 2004 | Diamond and Related Materials2004，13，： | 1 |
| 14 | Semi-syntheses and eytotoxieity of styryl-laetone derivatives 显示文摘 | Bermejo A Leonce S Cabedo Nuria | 1999 | J Nat Prod1999，62，8： | 1 |
| 15 | Leukaemia Lymphoma, and Myeloma mortality in the vicinity of nuclear power plants and nuclear fuel facilities in Spain 显示文摘 | Gonzalo Lopez - Abente Nuria Aragone' s Marina Polla' n | 1999 | Cancer Epidemiolohy1999，8，： | 1 |
| 16 | A GIS-based multivariate statistical analysis for shallow landslide susceptibility mapping in La Pob lade Lillet area(Eastern Pyrenees, Spain)显示文摘 | Nuria S B Baeza B Jordi C | 2003 | Natural Hazards2003，30，： | 1 |
| 17 | New product internal performance and market perform- ance: evidence from spanish firms regarding the role of trust, interfunetional integraion, and innovation type 显示文摘 | NURIA GARCIA M J S JUAN A TRESPALACIOS | 2008 | Technovation2008，，28： | 1 |
| 18 | Wheat nitrogen metabolism during grain filling: comparative role of glumes and the flag leaves 显示文摘 | Lopes Marta S Cortadellas Nuria Kichey T | 2006 | Planta2006，225，： | 1 |
| 19 | FfIR Technique used to study acidic paper manuscripts dating from the thirteenth to the sixteenth century from the archive of the crown of Aragon 显示文摘 | Nuria F M Carme S | 2007 | The Book and Paper Group Annual2007，，26： | 1 |
| 20 | Involvement of VIP on BDNF-induced somatostatin gene expression in cultured fetal rat cerebral cortical cells显示文摘 | Gemma Villuendas Franco Sánchez-Franco Nuria Palacios Miriam Fernández Lucinda Cacicedo | 2001 | Molecular Brain Research2001，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员