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| 1 | Anti-hypercholesterolemic effect of kenaf(Hibiscus cannabinus L.)seed on high-fat diet Sprague dawley rats显示文摘Objective:To determine? the anlihypercholesterolemic effects of kenaf seed samples and compare with the commercial hypocholesterolemic drug on serum lipids profiles and malondialdehyde(MDA) level in the rat.Methods:Kenaf seed oil(KSO),microencapsulated kenaf seed oil(MKSO),kenaf seed extract(KSE) and defatted kenaf seed meal(DKSM) were prepared and phytocHemicals screening on these samples were done prior in viro study.Phenolic compounds in KSF.were quantified using high performance liquid chromatography.There were 40(divided in eight diet groups of 5) male Sprague dawley rats adapted lo normal standard diet or hypercholesterolemic diet(HD) with or without the treatment of these kenaf samples for 32 days.Results:All the kenaf samples exhibited to contain most of the major phytocliemicals.KSE possessed gallic acid,tannic acid,catechin.benzaldehyde.benzoic acid,syringic acid,sinapic acid,ferulic acid,naringin acid,and protocatechuic acid.The significant higher(P<0.05) serum total cholesterol,low density lipoprotein cholesterol and MDA levels in HD group without treatment than the normal control group suggested the hypercholesterolemia was induced by the Incorporation of cholesterol into diet.KSE exhibited higher cholesterol-lowering properties due to the significant lower(P<0.05)in serum triglycerides,total cholesterol and MDA levels.KSF showed the highest efficiency of cholesterol-lowering activity,followed by KSO.MKSO and DKSM.Conclusions:DKSM.MKSO.KSO and KSE appeared lo have comparable anti-hypercholesterolemic effect with the commercial hypocholesterolemic drug.Hence,kenaf seed could be used as an alternative natural source lo replace the synthetic hypocholosterolemic drugs. | Ng Shy Kai Tee Ai Nee Elaine Lai Chia Ling Tan Chin Ping Long Kamariah Nyam Kar Lin | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，1： | 2 |
| 2 | Management of colonic lipomas显示文摘 | Chung YF Ho YH Nyam DCNK | 1998 | Aust N Z J Surg1998，68，2： | 1 |
| 3 | Extraction of tocopherol-enriched oil from Kalahari melon and roselle seeds by superieritieal fluid extraction ( SFE-CO2 ) 显示文摘 | Kar Lin Nyam Chin Ping Tan Roselina Karim | 2010 | Food Chemistry2010，119，3： | 1 |
| 4 | Glycobiology of schistosomiasis 显示文摘 | Cummings RD Nyame AK | 1996 | FASEB J1996，10，1： | 1 |
| 5 | Long-term results of surgery for chronic constipation显示文摘 | Denis C. N. K. Nyam M.D. John H. Pemberton M.D. Duane M. Ilstrup M.S. Doris M. Rath R.N | 1997 | Diseases of the Colon & Rectum1997，，3： | 1 |
| 6 | Permeability of normal and lightweight mortars 显示文摘 | Nyame B K | 1985 | Magazine of Concrete Research1985，37，130： | 1 |
| 7 | Antigenic glycans in parasitic infections: implications for vaccines and diagnostics显示文摘 | Nyame AK Kawar ZS Cummings RD | 2004 | Arch Biochem Biophys2004，426，2： | 1 |
| 8 | Management of colonic lipomas显示文摘 | Chung YF HO YH Nyam DCNK | 1998 | Aust N ZJ Surg1998，68，2： | 1 |
| 9 | Physicochemical properties of Kalahari melon seed oil following extractions using solvent and aqueous enzymatic methods显示文摘 | Nyam K L Tan C P Che Man Y B | 2009 | International Journal of Food Science and Technology2009，44，4： | 1 |
| 10 | Long-term results of surgery for chronic constipation显示文摘 | NYAM DCNK PEMVERTON JH ILSTRUP DM | 1997 | Dis Colon Rectum1997，40，： | 1 |
| 11 | Schistosoma mansoni infection in humans and primates induces cytolytic antibodies to surface Lex determinants on myeloid cells显示文摘 | Nyame AK PilcherJB Tsang VCW et a1 | 1996 | Exp Parasitol1996，82，2： | 1 |
| 12 | Optimization of supercritical?uidextraction of phytosterol from roselle seeds with a central composite designmodel显示文摘 | K L Nyam C P Tan O M Lai | 2010 | Food and Bioproducts Processing2010，88，23： | 1 |
| 13 | Polyaniline / Poly(methyl methacrylate) Coaxial Fibers: The Fabrication and Effects of the Solution Properties on the Morphology of Electrospun Core Fibers 显示文摘 | Dong H Nyame V | 2004 | Journal of Polymer Science: Part B: Polymer Physics2004，42，： | 1 |
| 14 | The surgical management of colorectal complications from irradiation for carcinoma of the cer- vix显示文摘 | Yegappan M Ho YH Nyam D | 1998 | Ann Acad Med Singapore1998，27，5： | 1 |
| 15 | Current advances and controversies in the surgical therapy for anorectal motility disorders显示文摘 | Nyam DC Pemberton JH | 1997 | Dig Dis1997，15，： | 1 |
| 16 | Mgnagement of colonic lipomas显示文摘 | CHUNG YF HO YH NYAM DC | 1998 | Aust NZJ Surg1998，68，2： | 1 |
| 17 | The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x显示文摘 | Van Die I Van Vliet S J Nyame A K | 2003 | Glycobiology2003，13，6： | 1 |
| 18 | Antigenic glycans in parasitic infections: implications for vaccines and diagnostics显示文摘 | A Kwam Nyame Ziad S Kawar Richard D C | 2004 | Archives of Biochemistry and Biophysics2004，426，： | 1 |
| 19 | Forest and forestry research and education in Mongolia显示文摘 | Nyam -Osor B Don K L Jamsran T | 2011 | Journal of Sustainable Forestry2011，30，6： | 1 |
| 20 | long-tenn results of continence after lat-eral internal sphlncterotomy for chronic anal fissure显示文摘 | Nyam D pemberton JH | 1997 | Dis Colon Rectum1997，40，12： | 1 |
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