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1Reduction patterns of Japanese encephalitis incidence following vaccine introduction into long-term expanded program on immunization in Yunnan Province,China显示文摘Background:Japanese encephalitis(JE)is a leading cause of childhood viral encephalitis both at global level and in China.Vaccination is recommended as a key strategy to control JE.In China most JE cases have been reported in southwest provinces,which include Yunnan.In this study,we quantify the epidemiological shift of JE in Yunnan Province from 2005 to 2017,covering before and after the introduction of JE vaccination into routine Expanded Program on Immunization(EPI)in 2007.Methods:We used routinely collected data in the case-based JE surveillance system from 2005 through 2017 in Yunnan.Cases were reported from hospital and county-level Centers for Disease Control in line with the National JE Surveillance Guideline.Epidemiological data were extracted,analysed and presented in appropriate ways.Immunization coverage was estimated from actual JE doses administered and new births for each year.Results:A total 4780 JE cases(3077 laboratory-confirmed,1266 clinical and 437 suspected)were reported in the study period.Incidence of JE(per 100000 population)increased from 0.95 in 2005 to 1.69 in 2007.With increase in vaccination coverage,incidence rates decreased steadily from 1.16 in 2009 to 0.17 in 2017.However,seasonality remained similar across the years,peaking in June-September.Banna(bordering Myanmar and Laos),Dehong(bordering Myanmar),and Zhaotong(an inland prefecture)had the highest incidence rates of 2.3,1.9,and 1.6,respectively.97%of all cases were among local residents.As vaccination coverage increased(and incidence decreased),proportion of JE cases among children<10 years old decreased from 70%in 2005 to 32%in 2017,while that among adults>20 years old increased from 12 to 48%.There were a large number of JE cases with unknown treatment outcomes,especially in the earlier years of the surveillance system.Conclusions:The 13-year JE surveillance data in Yunnan Province showed dramatic decrease of total incidence and a shift from children to adults.Improving vaccination coverage,including access to adults at risk,and strengthening the JE surveillance system is needed to further control or eliminate JE in the province.Xiao-Ting Hu Qiong-Fen Li Chao Ma Zhi-Xian Zhao Li-Fang He Ting-Ting Tang Wen Yu Philip Owiti 2019Infectious Diseases of Poverty2019,8,6:3
2Prevalence of Tuberculosis among Close Contacts of Index Cases in 27 Universities in Beijing,China,2017-2018显示文摘The World Health Organization(WHO)launched the‘End TB Strategy’,which aims to reduce the mortality and incidence rate of tuberculosis(TB)by 95% and 90% by 2035,respectively,compared with the levels in 2015.To achieve these targets and milestones,the strategy set three pillars and 10 indicators,one of which is systematic screening of contacts and high-risk groups[1].ZHAO Fei ZHANG Zhi Guo MA Shu Bo YANG Zhen HE Yan Ping WANG Lu Qin OWITI Philip MA Chao LI Tao DU Xin ZHANG Can You CHENG Jun WANG Li Xia HE Guang Xue ZHANG Hui LI Ke Xin 2020Biomedical and Environmental Sciences2020,33,10:2
3Assessment of household ownership of bed nets in areas with and without artemisinin resistance containment measures in Myanmar显示文摘Background:Myanmar lies in the Greater Mekong Subregion where there is artemisinin-resistant Plasmodium falciparum malaria.As the artemisinin compound is the pillar of effective antimalarial therapies,containing the spread of artemisinin resistance is a national and global priority.The use of insecticide-treated bed nets/long-lasting insecticidal nets(ITNs/LLINs)is the key intervention for ensuring the reduction of malaria transmission and the spread of resistant strains,and for eventually eliminating malaria.This study aimed at assessing household ownership of,access to,and utilization of bed nets in areas of Myanmar with and without artemisinin resistance containment measures.Methods:Secondary data from a nationwide community-based malaria survey conducted by the National Malaria Control Program in 2014 were analyzed.Based on evidence of artemisinin resistance,Myanmar was divided into tiers 1,2,and 3:townships in tiers 1 and 2 were aggregated as the Myanmar Artemisinin Resistance Containment(MARC)areas and were compared with tier 3 townships,which were defined as non-MARC areas.The chi-square test was used to compare groups,and the level of significance was set at P≤0.05.Results:Of the 6328 households assessed,97.2%in both MARC and non-MARC areas had at least one bed net(any type),but only 63%of households had ITNs/LLINs.Only 44%of households in MARC areas and 24%in non-MARC areas had adequate numbers of ITNs/LLINs(one ITN/LLIN per two persons,P<0.001).Nearly 44%of household members had access to ITNs/LLINs.Regarding the utilization of ITNs/LLINs,45%of household members used them in MARC areas and 36%used them in non-MARC areas(P<0.001,desired target=100%).Utilization of ITNs/LLINs among children aged below five years and pregnant women(high malaria risk groups)was low,at 44%and 42%,respectively.Conclusions:This study highlights the nationwide shortfalls in the ownership of,access to,and utilization of ITNs/LLINs in Myanmar,which is of particular concern in terms of containing the spread of artemisinin resistance.It highlights the need for priority attention to be paid and mobilization of resources in order to improve bed net coverage and utilization through bed net distribution and/or social marketing,information dissemination,and awareness-raising.Thae Maung Maung Tin Oo Khin Thet Wai Thaung Hlaing Philip Owiti Binay Kumar Hemant Deepak Shewade Rony Zachariah Aung Thi 2018Infectious Diseases of Poverty2018,7,1:1
4Operational research capacity building through the Structured Operational Research Training Initiative(SORT-IT)in China:implementation,outcomes and challenges显示文摘Background:Chinese Center for Disease Control and Prevention(China CDC)introduced the Structured Operational Research Training Initiative(SORT IT)into China to build a special capacity and equip public health professionals with an effective tool to support developing countries in strengthening their operational research.The paper aims to investigate and analyze the implementation,outcomes and challenges of the first cycle of SORT IT in China.Ning Feng Jeffrey Karl Edwards Philip Odhiambo Owiti Guo-Min Zhang Zulma Vanessa Rueda Vallejo Katrina Hann Shui-Sen Zhou Myo Minn Oo Elizabeth Marie Geoffroy Chao Ma Tao Li Jun Feng Yi Zhang Xiao-Ping Dong 2021Infectious Diseases of Poverty2021,10,3:1
5Knowledge,access and utilization of bednets among stable and seasonal migrants in an artemisinin resistance containment area of Myanmar显示文摘Background:Myanmar lies in the Greater Mekong sub-region of South-East Asia faced with the challenge of emerging resistance to artemisinin combination therapies(ACT).Migrant populations are more likely than others to spread ACT resistance.A vital intervention to reduce malaria transmission,resistance spread and eliminate malaria is the use of bed nets.Among seasonal and stable migrants in an artemisinin resistance containment region of Myanmar,we compared a)their household characteristics,b)contact with health workers and information material,and c)household knowledge,access and utilization of bed nets.Methods:Secondary data from community-based surveys on 2484 migrant workers(2013 and 2014,Bago Region)were analyzed of which 37%were seasonal migrants.Bed net access and utilization were assessed using a)availability of at least one bed net per household,and b)one bed net per two persons,and c)proportion of household members who slept under abed net during the previous night(Indicator targets=100%).Results:Over 70%of all migrants were from unstable work settings with short transitory stays.Average household size was five(range 1-25)and almost half of all households had children under-five years.Roughly 10%of migrants were night-time workers.Less than 40%of households had contact with health workers and less than 30%had exposure to information education and communication(IEC)materials,the latter being significantly lower among seasonal migrants.About 70%of households were aware of the importance of insecticide-treated bed-nets/long-lasting insecticidal nets(ITNs/LLINs),but knowledge on insecticide impregnation and retreatment of ITNs was poor(<10%).Although over 95%of households had access to at least one bed net,the number with one bed net per two persons was grossly inadequate(13%for stable migrants and 9%for seasonal migrants,P=0.001).About half of all household members slept under a bed net during the previous night.Conclusions:This study reveals important short-falls in knowledge,access and utilization of bed nets among migrants in Myanmar.Possible ways forward include frequent distribution campaigns to compensate for short transitory stays,matching household distributions to household size,enhanced information campaigns and introducing legislation to make mosquito repellents available for night-time workers at plantations and farms.Better understanding through qualitative research is also merited.Wint Phyo Than Tin Oo Khin Thet Wai Aung Thi Philip Owiti Binay Kumar Hemant Deepak Shewade Rony Zachariah 2017Infectious Diseases of Poverty2017,6,1:0
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