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| 1 | Coupled modeling of tumour angiogenesis, tumour growth,and blood perfusion显示文摘This paper proposes a more realistic mathematical simulation method to investigate the dynamic process of tumour angio-genesis by fully coupling the vessel growth,tumour growth and associated blood perfusion.The tumour growth and angiogenesis are coupled by the chemical microenvironment and the cell-matrix interaction.The haemodynamic calculation is carried out on the new vasculature,and an estimation of vessel collapse is made according to the wall shear stress criterion.The results are consistent with physiological observations,and further confirm the application of the coupled model feedback mechanism.The model is available to examine the interactions between angiogenesis and tumour growth,to study the change in the dynamic process of chemical environment and the vessel remodeling. | Y.Cai,1,2 S.X.Xu,1,a) J.Wu,3 and Q.Long 2,b) 1) Department of Mechanics and Engineering Science,Fudan University,Shanghai 200433,China 2) Brunel Institute for Bioengineering,School of Engineering and Design,Brunel University,Uxbridge,Middlesex,UK 3) School of Naval Architecture,Ocean and Civil Engineering,Shanghai Jiaotong University,Shanghai 200240,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，4： | 8 |
| 2 | Pancreatic cancerexosomes initiate pre-metastatic niche formation in the liver 显示文摘 | Costa-Silva B Aiello N M Ocean A | 2015 | Nat Cell Biol2015，17，6： | 1 |
| 3 | Part II:Idealized model of the circulation pat-tern and amplitude in oceanic basins显示文摘 | Stommel H M Arons A B 1960:On the abyssal circulation ofthe World Ocean | 1960 | Deep-Sea Research 6:217-2331960，6，： | 1 |
| 4 | Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma 显示文摘 | Siegel AB Cohen EI Ocean A | 2008 | J Clin Oncol2008，26，18： | 1 |
| 5 | Chemotherapyinduced peripheral neuropathy: pathogenesis and emerging therapies显示文摘 | Ocean A J Vahdat LT | 2004 | Support Care Cancer2004，129，9： | 1 |
| 6 | Activity of fractionated radioimmunotherapy (RAIT) with 90Y clivatuzumab tetraxetan (90Y-hPAM4) plus gemcitabine (Gem) in advanced pancreatic cancer (APC):Final results from a two-part study显示文摘 | Ocean A J Guarino M J Pennington KL | | 0，，4： | 1 |
| 7 | A phase I trial of oblimersen sodium in combination with cisplatin and 5 - fluorouracil in patients with advanced esophageal, gastroesophageal junction , and gastric carcinoma显示文摘 | Raab R Sparano JA Ocean A J | 2010 | Am J Oncol2010，33，： | 1 |
| 8 | 显示文摘 | Du L Li D Zhu T : New alkaloids and diterpenes from a deep ocean sediment derived fungus PeniciUium sp | 2009 | Tetrahedron2009，65，5： | 1 |
| 9 | Pilot study of sirolimus in cirrhotic patients with advanced hepatoeellular carcinoma 显示文摘 | Siegel A B Cohen E I Ocean A | 2008 | Hepatology2008，，： | 1 |
| 10 | Phase Ⅱ trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma显示文摘 | Siegel AB Cohen EI Ocean A | 2008 | J Clin 0ncol2008，26，18： | 1 |
| 11 | Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma显示文摘 | Siegel AB Cohen EI Ocean A | 2008 | J Clin Oncol2008，26，： | 1 |
| 12 | Phase II trial eval- uating the clinical and biologic effects of bevacizumab in unr- esectable hepatocellular carcinoma显示文摘 | SIEGEL AB COHEN El OCEAN A | 2008 | J Clin Oncol2008，26，18： | 1 |
| 13 | PhaseⅡtrial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma显示文摘 | Siegel AB Cohen EI Ocean A | 2008 | Clin Oncol2008，26，18： | 1 |
| 14 | Chemotherapy induced peripheral neuropathy : pathogenesis and emerging t herapies 显示文摘 | Ocean A] Vahdat LT | 2004 | Support Care Cancer2004，12，9： | 1 |
| 15 | Chemotherapy-induced peripheral neurupathy : pathogenesis and emerging therapies 显示文摘 | OCEAN A J VAHDAT L T | 2004 | Support Care Cancer2004，12，9： | 1 |
| 16 | I: Encrustations from the Line Island Archipelago 显示文摘 | Aplin A C Cronan D S Ferromanganese oxide deposits from Central Pacific Ocean | 1985 | Geocbim Cosmochim Acta1985，49，： | 1 |
| 17 | Phase/i study of PS-341 (VELCADE, bortezomib) with or without irinoteean in patients (pts) with advanced gastric adenocarcinomas (AGA)显示文摘 | Ocean A J SchnoU-Sussman F Chert X | 2005 | Gastrointestinal Cancers Symposium2005，31，： | 1 |
| 18 | Timing of Serpenti- the Josephine Ophiolite: Implications for Moho显示文摘 | COULTON nizat Ion in the Oceanic Geophysical A J HARPER G D | 1992 | EOS Transactions American Union1992，73，43： | 1 |
| 19 | Quadratic and cubic eddy-viscosity models in turbulent supercavitating flow computation显示文摘Quadratic and cubic non-linear eddy-viscosity turbulence models(NLEVM) with low Reynolds number(Re) correction were presented to provide better description of anisotropic turbulence stresses in the numerical prediction of supercavitating flows,which are accompanied with large density ratio and large-scaled swirling flow structures.The applications of the NLEVM were carried out through a self-developed cavitation codes,coupled with a cavitation model based on the transport equation of liquid phase.These N... | Ying Chen,~(1,a)) Chuanjing Lu,~(1,2) and Xin Chen~1 1)Department of Engineering Mechanics,School of Naval Architecture,Ocean and Civil Engineering, Shanghai Jiao Tong University,Shanghai 200240,China 2)State Key Laboratory of Ocean Engineering,Shanghai Jiao Tong University,Shanghai 200240,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，3： | 1 |
| 20 | Phase Ⅱ trial evaluating the clinical and biologic effects of hevacizumab in unresectable hepatocellular carcinoma显示文摘 | Siegel AB Cohen EI Ocean A | 2008 | J Clin Oncol2008，26，18： | 1 |
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