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    题名 作者 年代 出处 被引量
1Anti-trypanoso- mal potential of Eucalyptus comaldulensis显示文摘Kabiru YA Ogbadoyi EO Okogun JI 2013British J Phar- macol Toxicol2013,4,2:1
2Difference in mycorrhizal infection and P uptake of sweet potato culti vars (lpomaea batatas) during their early growth in three soils 显示文摘MULONGOY K COLLENS A OKOGUN J A 1998Biology and Fertility Soils1998,7,:1
3C24-C27 de graded triterpanes in Nigerian petroleum: Novel molecular markers of source/input or organic maturation显示文摘Ekweozor C M Okogun J I Ekong D E U 1981Journal of Geochemical Exploration1981,15,13:1
4Petroleum geochemistry of an ancient clay-filled canyon in the western Niger delta,Nigeria显示文摘Udo O T Ekweozor C M Okogun J I 0,,:1
5Myrianthic acid:A triterpene acid from the rootwood of Myrianthus arboreus显示文摘 Okogun JI Okorie DA 1984Phytochemistry1984,23,:1
6C24-C27 degraded triterpanes in Nigerian petroleum: Novel molecular markers of source/input or organic maturation 显示文摘Ekweozor C M Okogun J I Ekong D E U 1981Journal of Geochemical Ex- ploration1981,15,13:1
7C 24-C 27 degraded triterpanes in Nigerian petroleum:Novel molecular markers of source/input or organic maturation显示文摘Ekweozor C M Okogun J I Ekong D E U 1981Journal of Geochemical Exploration1981,15,13:1
8Antihelmintic activity of the stern bark extracts of Berlina grandiflora and one of its active principles, betulinic acid 显示文摘Enwerem N M Okogun J I Wambebe C O 2001Phytomedicine2001,8,2:1
9Use of 7-Chloro-4-Nitrobenzo-2-oxa-1,3-diazole for Determining Cysteine and Cystine in Cereal and Legume Seeds显示文摘Akinyele A F Okogun J I Faboya O P 1999Journal of Agricultural Food Chemistry1999,47,6:1
10Hypoestoxide inhibits tumor growth in the mouse CT26 colon tumor model显示文摘AIM: To evaluate the effect of the natural diterpenoid, hypoestoxide (HE) on the growth of established colon cancer in mice. METHODS: The CT26.WT mouse colon carcinoma cell line was grown and expanded in vitro. Following the expansion, BALB/c mice were inoculated s.c. with viable tumor cells. After the tumors had established and developed to about 80-90 mm3, the mice were started on chemotherapy by oral administration of HE, 5-fluorouracil (5-FU) or combination. RESULTS: The antiangiogenic HE has previously been shown to inhibit the growth of melanoma in the B16F1 tumor model in C57BL/6 mice. Our results demonstrate that mean volume of tumors in mice treated with oral HE as a single agent or in combination with 5-FU, were significantly smaller (> 60%) than those in vehicle control mice (471.2 mm3 vs 1542.8 mm3, P < 0.01). The significant reductions in tumor burden resulted in pronounced mean survival times (MST) and increased life spans (ILS) in the treated mice. CONCLUSION: These results indicate that HE is an effective chemotherapeutic agent for colorectal cancer in mice and that HE may be used alone or in combination with 5-FU.Emmanuel A Ojo-Amaize Howard B Cottam Olusola A Oyemade Joseph I Okogun Emeka J Nchekwube 2007World Journal of Gastroenterology2007,13,34:0
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