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14篇 您的检索式:作者名="Okten F"
    题名 作者 年代 出处 被引量
1Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun 2003World Journal of Gastroenterology2003,9,10:5
2Is celiac artery compression syndrome genetically inherited?:a case series from a family and review of the literature显示文摘Okten RS Kucukay F Tola M 2012Eur J Radiol2012,81,:1
3Percutaneous management of malignant biliary disease:factors influencing the ability to overcome the stricture显示文摘Kücükay F Okten RS Yurdakul M 2011Diagn Interv Radiol2011,17,2:1
4Microscopic polyangiitis with diffuse peribronchovascular nodular involvement : case report 显示文摘Okten F Gtlnay S Giinay E 2010Respiratory Medicine CME2010,3,3:1
5Is celiac artery compres-sion syndrome genetically inherited? :a case series from afamily and review of the literature 显示文摘Okten RS Kucukay F Tola M 2012Eur J Radiol2012,81,:1
6Computed tomography findings in 66 patients with malignant pleural mesothelioma due to environmental exposure to asbestos显示文摘Okten F Koksal D Onal M 2006Clin Imaging2006,30,3:1
7Three-dimensional volume rendering digital subtraction angiography in comparison with two-dimensional digital subtraction angiography and rotational angiography for detecting aneurysms and their morphological properties in patients with subarachnoid hemorrhage显示文摘Kucukay F Okten RS Tekiner A 2012Eur J Radiol2012,81,10:1
8Three-dimen- sional volume rendering digital subtraction angiography in comparison with two-dimensional digital subtraction angiography and rotational angiography for detecting an- eurysms and their morphological properties in patients with subarachnoid hemorrhage 显示文摘Kucukay F Okten R S Tekiner A 2012Eur J Radiol2012,81,10:1
9Gastric subepithelial masses: Evaluation of multidetector CT (multiplanar reconstruction and virtual gastroscopy) versus endoscopic ultrasonography显示文摘OKTEN R S KACAR S KUCUKAY F 2012Abdom Imaging2012,37,4:1
10Three dimen- sional volume rendering digital subtraction angiography in comparison with two-dimensional digital subtraction angiography and rotational angiography for detecting aneurysms and their morphological properties in pa- tients with subarachnoid hemorrhage 显示文摘Kucukay F Okten RS Tekiner A 2012European Journal of Radiology2012,81,10:1
11Triple metallic stenting in malignant biliary obstructions 显示文摘Kucukay F Okten RS Yurdakul M 2011Diagn Interv Radiol2011,17,:1
12Is celiac artery compressionsyndrome genetically inherited?: A case series from a family andreview of the literature显示文摘Okten RS Kucukay F Tola M 2012Eur J Radiol2012,81,6:1
13Gastric subepithelial masses: Evaluation of multidetector CT (muhiplanar reconstruction and virtual gastroscopy) versus endoscopic ultrasonography 显示文摘Okten RS Kacar S Kucukay F 2012Abdom Imping2012,37,4:1
14Gastric subepithelial masses : Evaluation of mulfidetector CT (muhiplanar reconstruction and virtual gastroscopy) versus endoscopic ultrasonography显示文摘Okten RS Kacar S Kucukay F 2012Abdom Imaging2012,37,4:1
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