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| 1 | Role of cyclooxygenase-2 gene polymorphisms in pancreatic carcinogenesis显示文摘AIM:To evaluate the clinical significance of-765G/C and-1195G/A cyclooxygenase-2 (COX-2) gene polymorphisms in patients with pancreatic cancer (PC).METHODS:The study included 201 patients:85 with PC and 116 healthy controls.-765G/C and-1195G/A COX-2 gene polymorphisms were studied in DNA isolated from blood samples.The associations of the analyzed genotypes and clinical data at diagnosis were evaluated.RESULTS:We found an increased frequency of the homozygous-1195AA COX-2 genotype in patients with PC (53.7%) compared with the control group (21%) (P < 0.01).In contrast,the distribution of genotypeand allele frequencies of the-765G/C COX-2 polymorphism in the PC patients were not different from those in control groups.A correlation between presence of homozygous-1195AA COX-2 genotype and tumor size > 3 cm was observed (P < 0.05).Analyzed polymorphisms were unrelated to the patients' sex and age,nor to the presence of regional or distant metastases.CONCLUSION:These preliminary results indicate that the-1195G/A COX-2 polymorphism may play an important role in PC prognosis and carcinogenesis. | Renata Talar-Wojnarowska Anita Gasiorowska Marek Olakowski Pawel Lampe Beata Smolarz Hanna Romanowicz-Makowska Ewa Malecka-Panas | 2011 | World Journal of Gastroenterology2011，17，36： | 4 |
| 2 | Clinical value of serum neopterin, tissue polypeptide-specific antigen and CA19-9 levels in differential diagnosis between pancreatic cancer and chronic pancreatitis 显示文摘 | Talar-Wojnarowska R Gasiorowska A Olakowski M | 2010 | Pancreatology2010，10，6： | 1 |
| 3 | Hepaticojejunostomy vs. End-to-end Biliary Reconstructions in the Treatment of Iatrogenic Bile Duct Injuries显示文摘 | Beata Jab?ońska Pawe? Lampe Marek Olakowski Zygmunt Górka Andrzej Lekstan Tomasz Gruszka | 2009 | Journal of Gastrointestinal Surgery2009，，6： | 1 |
| 4 | Clinical value of serum neopterin, tissue polypeptide-speeifie antigen and CA19 -9 levels in differential diagnosis between pancreatic cancer and chronic panereatitis显示文摘 | Talar-Wojnarowska R Gasioruwska A Olakowski M | 2010 | Panereatology2010，10，6： | 1 |
| 5 | Clinical value of serum neopterin,tissue polypeptide-specific antigen and CA199 levels in differential diagnosis between pancreatic cancer and chronic pancreatitis显示文摘 | Talar-Wojnarowska R Gasiorowska A Olakowski M | 2010 | Pancreatology2010，10，6： | 1 |
| 6 | Clinical value of serum neopterin, tissue polypeptide specific antigen and CA19 9 levels in differential diagnosis between pancreatic cancer and chronic pancreatitis 显示文摘 | Talar-Wojnarowska R Gasiorowska A Olakowski M | 2010 | Pancreatology2010，10，6： | 1 |
| 7 | Neuroendocrine pancreatic carcinoma causing sinistral portal hypertension显示文摘 | Olakowski M Lampe P Bddys M | 2001 | Med Sci Monit2001，7，6： | 1 |
| 8 | Clin- ical value of serum neopterin, tissue polypeptide-specific antigen and CA19-9 levels in differential diagnosis between pancreatic cancer and chronic pancreatitis 显示文摘 | Talar-Wojnarowska R Gasiorowska A Olakowski M | 2010 | Pancreatology2010，10，6： | 1 |
| 9 | Clinical value of serum nepoterm ,tissue polypeptidespecific antigen and CA19-9 levels in differential diagnosis between pancreatic cancer and chronic pancreati- tis显示文摘 | Talar-Wojnarowska R Gasiorowska A Olakowski M | 2010 | Pancreatology2010，10，6： | 1 |
| 10 | Vascular endothelial growth factor (VEGF) genotype and serum concentration in patients with pancreatic adenocarcinoma and chronic pancreatitis显示文摘 | Talar-Wojnarowska R Gasiorowska A Olakowski M | 2010 | Journal of Physiology and Pharmacology2010，61，6： | 1 |
| 11 | Association between acute pancreatitis and COVID-19 infection:What do we know?显示文摘The disease caused by severe acute respiratory syndrome coronavirus 2(SARSCoV-2),also called coronavirus disease 2019(COVID-19),first originated in Wuhan,China,displaying atypical pneumonia-like respiratory symptoms in affected patients.SARS-CoV-2 primarily attacks the respiratory system,and the most common symptoms include cough,shortness of breath,and fever.However,its impact on the digestive system has been shown,and various clinical gastrointestinal manifestations of this disease have been recognized.Some reports have shown acute pancreatitis(AP)as the initial symptom in patients with COVID-19.AP may be a consequence of direct pancreatic damage by the virus because pancreatic acinar cells contain angiotensin-converting enzyme 2 receptor proteins,and SARS-CoV-2 can bind to these receptors,causing pancreatic injury.Moreover,AP may be a secondary indicator of cytokine storms and altered inflammatory responses.Our review of the literature shows that SARS-CoV-2 appears to be a new etiological infectious factor related to AP.In this manuscript,a comprehensive review of case reports and case series of patients with AP and COVID-19 is presented.All reports on COVID-19-associated AP are summarized.All cases are thoroughly analyzed and discussed in-depth. | Beata Jabłońska Marek Olakowski Sławomir Mrowiec | 2021 | World Journal of Gastrointestinal Surgery2021，13，6： | 0 |
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