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| 1 | Lack of CD44 variant 6 expression in rectal cancer invasive front associates with early recurrence显示文摘AIM: To investigate the prognostic value of CD44 variant 6 (CD44v6), a membranous adhesion molecule, in rectal cancer. METHODS: Altogether, 210 rectal cancer samples from 214 patients treated with short-course radiotherapy (RT, n = 90), long-course (chemo) RT (n = 53) or surgery alone (n = 71) were studied with immunohistochemistry for CD44v6. The extent and intensity of membranous and cytoplasmic CD44v6 staining, and the intratumoral membranous staining pattern, were analyzed.RESULTS: Membranous CD44v6 expression was seen in 84% and cytoplasmic expression in 81% of the cases. In 59% of the tumors with membranous CD44v6 expression, the staining pattern in the invasive front was determined as 'front-positive' and in 41% as 'front-negative'. The latter pattern was associated with narrower circumferential margin (P = 0.01), infiltrative growth pattern (P < 0.001), and shorter disease-free survival in univariate survival analysis (P = 0.022) when compared to the 'front-positive' tumors. CONCLUSION: The lack of membranous CD44v6 in the rectal cancer invasive front could be used as a method to identify patients at increased risk for recurrent disease. | Suvi Tuulia Avoranta Eija Annika Korkeila Kari Juhani Syrjnen Seppo Olavi Pyrhnen Jari Toivo Tapio Sundstrm | 2012 | World Journal of Gastroenterology2012，18，33： | 9 |
| 2 | 纸浆漂白新技术显示文摘 | Olavi Pikka Janne Vehmaa Jouni Mehto 安国兴 | 2002 | 国际造纸2002，21，1： | 7 |
| 3 | 中国的防护林系统:现状、问题与前景显示文摘中国进行不同类型的防护林系统建设始于50年代初期。经过40年的努力,其巨大的成功和这些林木特有的多用性,已引起了世界范围的关注。目前防护林网面积为3000万hm^2,可用林未体积为85000万m^3。防护林占全国造林总面积和森林恢复总面租的大约10%~13%,而且还提供了大量的林产品和非林产品。最近几年,防护林面积的年增量已经达到100万hm^2。中国森林覆盖率的逐年增加,并产生了显著的生态、经济和社会效益一定程度上就与此有关。发展防护林系统的主要限制因子是由于资金短缺、缺乏教育而造成的管理不力。对这些林木进行更好的管理,特进一步提高它们的经济、社会和环境效益。 | 李春阳 Jarkko Koskela Olavi Luukkanen 闵庆文 | 1999 | AMBIO-人类环境杂志1999，28，4： | 5 |
| 4 | Height increment of understorey Norway spruces under different tree canopies显示文摘Background:Stands having advance regeneration of spruce are logical places to start continuous cover forestry(CCF) in fertile and mesic boreal forests.However,the development of advance regeneration is poorly known.Methods:This study used regression analysis to model the height increment of spruce understorey as a function of seedling height,site characteristics and canopy structure.Results:An admixture of pine and birch in the main canopy improves the height increment of understorey.When the stand basal area is 20 m2ha-1 height increment is twice as fast under pine and birch canopies,as compared to spruce.Height increment of understorey spruce increases with increasing seedling height.Between-stand and within-stand residual variation in the height increment of understorey spruces is high.The increment of 1/6 fastest-growing seedlings is at least 50%greater than the average.Conclusions:The results of this study help forest managers to regulate the density and species composition of the stand,so as to obtain a sufficient height development of the understorey.In pure and almost pure spruce stands,the stand basal area should be low for a good height increment of the understorey. | Olavi Laiho Timo Pukkala Erkki Lhde1 | 2014 | Forestry Studies in China2014，16，1： | 5 |
| 5 | Optimizing any-aged management of mixed boreal forest under residual basal area constraints显示文摘The current trend of forest management in many countries is reduced use of clear-felling and planting, and increased use of continuous cover management. In Finland, the new forest act of 2014 made all types of cuttings equally allowable on the condition that if the post-cutting residual stand basal area is too low, the stand must be regenerated within certain time frame. Forest landowner can freely choose between evenand uneven-aged management. This study developed a method for optimizing the timing and type of cuttings without the need to categorize the management system as either even-aged or uneven-aged. A management system that does not set any requirements on the sequence of post-cutting diameter distributions is called any-aged management. Planting or sowing was used when stand basal area fell below the required minimum basal area and the amount of advance regeneration was less than required in the regulations. When the cuttings of 200 stands managed earlier with even-aged silviculture were optimized with the developed system, final felling followed by artificial regeneration was selected for almost 50% of stands. Reduction of the minimum basal area limit greatly decreased the use of artificial regeneration but improved profitability, suggesting that the truly optimal management would be to use natural regeneration in financially mature stands. The optimal type of thinning was high thinning in 97–99 % of cases. It was calculated that the minimum basal area requirement reduced the mean net present value of the stands by 12–16 % when discount rate was 3–5 %. | Timo Pukkala Erkki L?hde Olavi Laiho | 2014 | Journal of Forestry Research2014，25，3： | 5 |
| 6 | How to understand a community-Community assessment for the promotion of health-related Physical activity显示文摘 | Olavi Paronen | 1998 | Patient Education and Counseling1998，33，： | 1 |
| 7 | Aryl hydrocarbon receptor nuclear translocator and upstream stimulatory factor regulate cytochrome P4502A5 transcription through a common E-box site显示文摘 | Satu A Virpi L Olavi P | 2007 | Journal of Molecular Biology2007，，369： | 1 |
| 8 | Ahl-stageTM酸加水分解とォゾン漂白による相乘效果显示文摘 | 福沢民雄 Pikka Olavi Vehmaa Janne | 2003 | 纸パ技协志2003，，7： | 1 |
| 9 | Age-related nutrient content and carbon isotope composition in the leaves and branches of Quercus aquifolioides along an altitudinal gradient显示文摘 | Chunyang Li Chengchun Wu Baoli Duan Helena Korpelainen Olavi Luukkanen | 2009 | Trees2009，，5： | 1 |
| 10 | Characteristics of nanobacteria and their possible role in stone formation显示文摘 | E. Olavi Kajander Neva Ciftcioglu Katja Aho Enrique Garcia-Cuerpo | 2003 | Urological Research2003，，2： | 1 |
| 11 | Nanobacteria: controversial pathogens in nephrolithiasis and polycystic kidney disease显示文摘 | E. Olavi Kajander Neva Ciftcioglu Marcia A. Miller-Hjelle J. Thomas Hjelle | 2001 | Current Opinion in Nephrology and Hypertension2001，，3： | 1 |
| 12 | Nanobacteria: An alternative mechanism for pathogenic intra-and extracellular calcification and stone formation Proc显示文摘 | E Olavi Kajander Neva Ciftc Ioglu | 1998 | Natl Acad Sci USA1998，95，： | 1 |
| 13 | Inhibition and induction of human cytochrome P450 enzymes: current status显示文摘 | Olavi P Miia T Jukka H | 2008 | Archives of Toxicology2008，82，10： | 1 |
| 14 | Cold-induced freezing tolerance in arabidopsis显示文摘 | Leslie A W Olavi J | 1999 | Plant Physiol1999，120，： | 1 |
| 15 | Depression is associated with poorer outcome of lumbar spinal stenosis surgery显示文摘 | Sanna S Timo A Olavi A | 2007 | Eur Spine J2007，16，7： | 1 |
| 16 | How to de- velop local physical activity promotion programmes with nation- al surports: the finish experience 显示文摘 | ILKKA VUORI OLAVI PARONEN PEKKA OJA | 1998 | Patient Edu Counsel1998，33，6： | 1 |
| 17 | Nanobacteria:An experimental neo-lithogenesis model显示文摘 | Garcia Cuerpo E Olavi Kajander E Ciftcioglu N | 2000 | Arch Esp Urol2000，53，4： | 1 |
| 18 | Efficacy of parenteral administration of three antimicrobial agent in treatment of clinical mastitis in lactating cows显示文摘 | KARINA H OLAVI E | 1998 | J Vet Med1998，212，3： | 1 |
| 19 | Dehydrins expression related to timing of bud burst in Norway spruce显示文摘 | Igor A. Yakovlev Daniel K. A. Asante Carl Gunnar Fossdal Jouni Partanen Olavi Junttila ?ystein Johnsen | 2008 | Planta2008，，3： | 1 |
| 20 | Depression is associated with poorer outcome of lumbar spinal stenosis surgery显示文摘 | Sanna S Timo A Olavi A | 2007 | Eur Spine J2007，16，7： | 1 |
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