|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Current position of ALPPS in the surgical landscape of CRLM treatment proposals显示文摘The Authors summarize problems,criticisms but also advantages and indications regarding the recent surgical proposal of associating liver partition and portal vein ligation(PVL)for staged hepatectomy(ALPPS)for the surgical management of colorectal liver metastases.Looking at published data,the technique,when compared with other traditional and well established methods such as PVL/portal vein embolisation(PVE),seems to give real advantages in terms of volumetric gain of future liver remnant.However,major concerns are raised in the literature and some questions remain unanswered,preliminary experiences seem to be promising.The method has been adopted all over the world over the last 2 years,even if oncological long-term results remain unknown,and benefit for patients is questionable.No prospective studies comparing traditional methods(PVE,PVL or classical 2 staged hepatectomy)with ALPPS are available to date.Technical reinterpretations of the original method were also proposed in order to enhance feasability and increase safety of the technique.More data about morbidity and mortality are also expected.The real role of ALPPS is,to date,still to be established.Large clinical studies,even if,for ethical reasons,in well selected cohorts of patients,are expected to better define the indications for this new surgical strategy. | Marcello Donati Gregor A Stavrou Karl J Oldhafer | 2013 | World Journal of Gastroenterology2013，19，39： | 16 |
| 2 | Laparoscopic step 1 ALPPS with microwave transection of theliver for Klatskin tumors:Is it worthwhile?显示文摘To the Editor:Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)was introduced in 2007[1].This technique is now used worldwide and has a wide spectrum of indications.However,scientific debate and un-regulated surgical experimentation concerning the application of this technique led the surgeons to organize the first Consensus Meeting[2]to build a scientific consensus.One of the most controversial indications to ALPPS is its application for Klatskin tumors.The aim of this letter is to ana- | marcello donati francesco basile karl j oldhafer | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，3： | 4 |
| 3 | Immunological aspects of liver cell transplantation显示文摘Within the field of regenerative medicine, the liver is of major interest for adoption of regenerative strategies due to its well-known and unique regenerative capacity. Whereas therapeutic strategies such as liver resection and orthotopic liver transplantation(OLT) can be considered standards of care for the treatment of a variety of liver diseases, the concept of liver cell transplantation(LCTx) still awaits clinical breakthrough. Success of LCTx is hampered by insufficient engraftment/long-term acceptance of cellular allografts mainly due to rejection of transplanted cells. This is in contrast to the results achieved for OLT where longterm graft survival is observed on a regular basis and, hence, the liver has been deemed an immuneprivileged organ. Immune responses induced by isolated hepatocytes apparently differ considerably from those observed following transplantation of solid organs and, thus, LCTx requires refined immunological strategies to improve its clinical outcome. In addition, clinical usage of LCTx but also related basic research efforts are hindered by the limited availability of high quality liver cells, strongly emphasizing the need for alternative cell sources. This review focuses on the various immunological aspects of LCTx summarizing data available not only for hepatocyte transplantation but also for transplantation of non-parenchymal liver cells and liver stem cells. | Felix Oldhafer Michael Bock Christine S Falk Florian WR Vondran | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 4 | Long-term experience af- ter ex situ liver surgery显示文摘 | Oldhafer KJ Lang H Schlitt HJ | 2000 | Surgery2000，127，5： | 1 |
| 5 | Two-step procedure in Budd-Chiari syndrome with severe intrahepatic Vena cava stenosis:Vena cava stenting and portocaval shunt显示文摘 | Oldhafer KJ Frerker M Prokop M | 1998 | Am J Gastroenterol1998，93，7： | 1 |
| 6 | Long-term experience after ex situ liver surgeu显示文摘 | KJ Oldhafer H Lang HJ Schlitt | 2000 | Surgery2000，127，5： | 1 |
| 7 | Ex vivo resection techniques in tissue-preserving surgery for liver malignancies显示文摘 | Raab R Schlitt HJ Oldhafer KJ | 2000 | Langenbecks Arch Surg2000，385，3： | 1 |
| 8 | ALPPS-where do we stand, where do we go?: eight recommendations from the first international expert meeting显示文摘 | Oldhafer K J Stavrou GA van Gulik TM | 2016 | Ann Surg2016，263，5： | 1 |
| 9 | Appraisal of transplantation of malignant tumors of liver special reference to early stage hepatocelluar carcinoma显示文摘 | Pichmayer R Weimann A Oldhafer KJ | 1998 | Eur J Surg Oncol1998，24，： | 1 |
| 10 | Long-term experience after ex s itu liver surgery显示文摘 | Oldhafer K J Lang H Schlitt H J | 2000 | Surgery2000，127，5： | 1 |
| 11 | Liver transplantation for metastatic neuoendocrine tumors显示文摘 | Lang H Oldhafer KJ Weimann A | 1997 | Ann Surg1997，225，： | 1 |
| 12 | Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: 1-dentification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue显示文摘 | Strassburg CP Oldhafer K Manns MP | 1997 | Mol Pharmaeol1997，52，： | 1 |
| 13 | ALPPS far Patients with Colorectal Liv- er Metastases: Effective Liver Hypertrophy, but Early Tumor R ecurrence 显示文摘 | Oldhafer KJ Donati M | 2014 | World J Surg2014，38，6： | 1 |
| 14 | 3-dimensional (3-D) visualization of theliver for planning extensive liver resections显示文摘 | Oldhafer KJ Hogemann D Stamm G | 1999 | Chirurg1999，70，3： | 1 |
| 15 | Long term experience after ex situ liver surgery显示文摘 | Oldhafer KJ Lang H Sehlitt HI | 2000 | Surgery2000，127，5： | 1 |
| 16 | Appraisal of transplantation for malignant tumours of the liver with special reference to early stage hepatocellular carcinoma显示文摘 | Pichlmayr R Weimann A Oldhafer K J Schlitt H J Tusch G Raab R | | European Journal of Surgical Oncology0，，： | 1 |
| 17 | Background and prognostic implications of perireperfusion tissue injuries in human liver transplants:a panel histochemical study显示文摘 | KIUCHI T OLDHAFER K J SCHLITT H J | 1998 | Transplantation1998，66，6： | 1 |
| 18 | Liver remnant hypertrophy induction – How often do we really use it in the time of computer assisted surgery?显示文摘 | GA Stavrou M Donati KI Ringe HO Peitgen KJ Oldhafer | 2012 | Advances in Medical Sciences2012，，2： | 1 |
| 19 | ALPPS for patientswith colorectal liver metastases : effective liver hypertrophy, butearly tumor recurrence 显示文摘 | Oldhafer KJ Donati M Jenner RM | 2014 | World J Surg2014，38，6： | 1 |
| 20 | Longtermexperience after ex situ liver surgery 显示文摘 | OLDHAFER K J LANG H SCHUTT H J | 2000 | Surgery2000，127，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员