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| 1 | Isocon analysis of migmatization in the Front Range, Colorado, USA 显示文摘 | Olsen S N Grant J A | 1991 | Metamorphic Geology1991，9，： | 2 |
| 2 | Influence of different second generation antipsychotics on the QTc interval: A pragmatic study显示文摘AIM To investigate whether differential influence on the QTc interval exists among four second generation antipsychotics(SGAs) in psychosis.METHODS Data were drawn from a pragmatic, randomized headto-head trial of the SGAs risperidone, olanzapine, quetiapine, and ziprasidone in acute admissions patients with psychosis, and with follow-up visits at discharge or maximally 6-9 wk, 3, 6, 12 and 24 mo. Electrocardiograms were recorded on all visits. To mimic clinical shared decision-making, the patients were randomized not to a single drug, but to a sequenceof the SGAs under investigation. The first drug in the sequence defined the randomization group, but the patient and/or clinician could choose an SGA later in the sequence if prior negative experiences with the first one(s) in the sequence had occurred. The study focuses on the time of, and actual use of the SGAs under investigation, that is until treatment discontinuation or change, in order to capture the direct medication effects on the QTc interval. Secondary intention-to-treat(ITT) analyses were also performed. RESULTS A total of 173 patients, with even distribution among the treatment groups, underwent ECG assessments. About 70% were males and 43% had never used antipsychotic drugs before the study. The mean antipsychotic doses in milligrams per day with standard deviations(SD) were 3.4(1.2) for risperidone, 13.9(4.6) for olanzapine, 325.9(185.8) for quetiapine, and 97.2(42.8) for ziprasidone treated groups. The time until discontinuation of the antipsychotic drug used did not differ in a statistically significant way among the groups(Log-Rank test: P = 0.171). The maximum QTc interval recorded during follow-up was 462 ms. Based on linear mixed effects analyses, the QTc interval change per day with standard error was-0.0030(0.0280) for risperidone;-0.0099(0.0108) for olanzapine;-0.0027(0.0170) for quetiapine, and-0.0081(0.0229) for ziprasidone. There were no statistically significant differences among the groups in this regard. LME analyses based on ITT groups(the randomization groups), revealed almost identical slopes with-0.0063(0.0160) for risperidone,-0.0130(0.0126) for olanzapine,-0.0034(0.0168) for quetiapine, and-0.0045(0.0225) for ziprasidone. CONCLUSION None of the SGAs under investigation led to statistically significant QTc prolongation. No statistically significant differences among the SGAs were found. | Roy E Olsen Rune A Kroken Sigmund Bj?rhovde Kristina Aanesen Hugo A J?rgensen Else-Marie L?berg Erik Johnsen | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 3 | On the exact, carson and image the theories for wires at or above the earth's interface显示文摘 | Olsen R G Pankaskie T A | 1983 | IEEE Trans on PAS1983，102，4： | 1 |
| 4 | Androgen influence on lacrimal gland apoptosis, necrosis, and lymphocytic infiltration 显示文摘 | AzzaroLo AM Wood RL Mircheff AK Richters A Olsen E | 1999 | Invest Ophthalmol Vis Sci1999，40，3： | 1 |
| 5 | Does neruoal damage of CA1 relate to spatial memory performance of rats subjected to transient forebrain ischemia显示文摘 | SCHEEL KRUGER J MLLER A | 1994 | Acta Neurol Scamal1994，89，： | 1 |
| 6 | Management of the non-descended testis: Doubtful value of luteinizing- hormone- releasing-hormone(LHRH) : A double - blind, placebo - controlled multicentre study显示文摘 | Olsen LH Genster HG Mosegaard A | 1992 | Int J Androl1992，15，2： | 1 |
| 7 | Gender differences in returns to and the acquisition of on-the-job training显示文摘 | Olsen R N Sexton E A | 1996 | Industrial Relations1996，35，1： | 1 |
| 8 | An electron microscopic study of some twinning and exsolution textures in microcline amazonites显示文摘 | Olsen A | 1977 | Physics and Chemistry of Minerals1977，1，3： | 1 |
| 9 | Nursing interventions and patient outcomes: A meta - analysis of studies 显示文摘 | Heater B Becker A Olsen R | 1988 | Nurse Res1988，37，： | 1 |
| 10 | Global patternsof in-fluenza a virus in wild birds显示文摘 | Olsen B Munster VJ Wallensten A | 2006 | Science2006，312，5772： | 1 |
| 11 | Differential regulation of VEGF, HIF1, and angiopoietin - 1, - 2, and - 4 by hypoxia and ionizing radia- tion in human glioblastoma 显示文摘 | Lund EL Hag A Olsen MWB | 2004 | Int J Cancer2004，108，6： | 1 |
| 12 | Preadmis-sion Use of Systemic Glucocorticoids and 30-Day Mortality Following Bleeding Peptic Ulcer: A Pop-ulation-Based Cohort Study显示文摘 | Olsen M Christensen S Riis A | 2010 | Am 1 Ther2010，17，1： | 1 |
| 13 | Effects of temperature on the diversity and community structure of known methanogenic groups and other archaeal in high Arctic peat显示文摘 | HΦJ L OLSEN R A TORSVIK V L | 2008 | The ISME Journal2008，2，1： | 1 |
| 14 | Thermoelas- tic properties of ScBz, TiBz, YB4 and HOB4: Ex- perimental and theoretical studies 显示文摘 | Waskowska A Gerward L Olsen J S | 2011 | Aeta Mater2011，59，： | 1 |
| 15 | Esthesioneuroblastoma: prognosis and management 显示文摘 | MORITA A EBERSOLD M J OLSEN K D | 1993 | Neurosurgery1993，32，： | 1 |
| 16 | Current status of InGaAs detector arrays for 1~3μm显示文摘 | Olsen G H Joshi A M Ban V S | 1991 | SPIE1991，1540，： | 1 |
| 17 | Kinetics of biodesulfurication of a high-sulfur coal 显示文摘 | Tonna A E Olsen T M | 1988 | Appl Biochem Biotechnol1988，18，1： | 1 |
| 18 | The influence of gender on theperception and response to investment risk:the case ofprofessional investors显示文摘 | Olsen R A Cox C M | 2001 | Journal of Psychology andFinancial Markets2001，2，： | 1 |
| 19 | Genetic char-acterization of an H1N2influenza virus isolated from apig in Indiana显示文摘 | Karasin A I Olsen C W Anderson G A | 2000 | J Clin Microbiol2000，38，6： | 1 |
| 20 | Catch to Landing Traceability and the Effects of Implementation:A Case Study from the Norwegian White Fish Sector显示文摘 | Donnelly K A M Olsen P | 2012 | Food Control2012，27，1： | 1 |
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