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| 1 | Detection of H.pylori DNA in gastric epithelial cells by in situ hybridization显示文摘AIM: To investigate the presence of H. pylori DNA withingastric epithelial cells in patients with H. pylori infection andits possible carcinogenic mechanism.METHODS: Total 112 patients, with pathologically confirmedchronic superficial gastritis, chronic atrophic gastritis,intestinal metaplasia, atypical hyperplasia or gastrio cancerwere studied .Among them, 28 were H. pylori negative and84 H. pylori positive. H. pylori DNA in gastric epithelialcells was detected by GenPoint catalyzed signalamplification system for in situ hybridization.RESULTS: In the H. pylori positive group, zero out of 24chronic superficial gastritis (0. 0 %), four out of 25precancerous changes (16.0 %) and thirteen out of 35gastric cancers (37. 1 %) showed H. pylori DNA in thenucleus of gastric epithelial cells, the positive rates of H.pylori DNA in the nucleus of gastric epithelial cells wereprogressively inoreased in chronic superficial gastritis,precancerous changes and gastric cancer groups (χ2 = 12.56, P = 0. 002); One out of 24 ohronic superficial gastritis(4.2 %), eleven out of 25 precancerous ohangas (44.0 %)and thirteen out of 35 gastric cancers (37. 1 %) showed H.pylori DNA in the cytoplasm of gastric epithelial cells (χ2 =10.86, P = 0.004). In the H. pylorinegative group, only onepatient with gastric cancer was found H. pylori DNA in thenucleus of gastric epithelial cells; Only two patients, onepatient with precancerous changes and another with gastriccancer, showed H. pylori DNA in the cytoplasm of gastricepithelial calls. Furthermore, H. pylori DNA must have been inthe ayteplasm as long as it existed in the nucleus of gastricepithelial cells.CONCLUSION: H. pyloriDNA exists both in the nucleus andthe cytoplasm of gastric epithelial cells in patients with H.pylori infections. The pathological progression from chronicsuperficial gastritis, precancerous changes to gastric canceris associated with higher positive rates of H. pylori DNApresence in the nucleus of gastric epithelial cells. | Xin-Liang Lu Ke-Da Oian Xun-Qiu Tang Yong-Liang Zhu Qin Du,Department of Digestive Diseases,Second Affiliated Hospital,Zhejiang University Medical College,Hangzhou 310009,Zhejiang Province,China | 2002 | World Journal of Gastroenterology2002，8，2： | 11 |
| 2 | EFFECT OF DYNAMIC STRAIN AGING ON LOW CYCLE FATIGUE BEHAVIOUR OF 18-8 AUSTENITIC STAINLESS STEEL显示文摘Studies were made of the symmetric tensile-compressive low cycle fatigue behaviour and theinfluence of dynamic strain aging(DSA)pre-treatment of 18-8 austenitic stainless steel.Within the testing amplitude range of strain.±0.5 % to±1.5 %,the three processes ofcyclic hardening,cyclic saturation and cyclic softening were observed.In the same amplitudeof strain,the peak stress of the samples pre-treated by DSA is higher than that of solid-solu-tion and cold working pre-treatment,but no remarkable differences of the fatigue lives ofthem were found.TEM observation shows that the uniform and stable dislocation networkswith high density form after DSA pre-treatment,which increases the cyclic peak stress.Thecyclic softening results from the low dislocation density and elongated cell structure with lowenergy. | PENG Kaiping CHEN Wenzhe OIAN Kuangwu Fuzhou University,Fuzhou,China teaching assistant,Department of Mechanical Engineering,Fuzhou University,Fuzhou 350002,China | 1993 | Acta Metallurgica Sinica(English Letters)1993，6，6： | 2 |
| 3 | Electrochemical overoxidation of conducting polypyrrole nitrate in aqueous solutions显示文摘 | LI Y OIAN R Y | 2000 | Electrochimica Acta2000，45，： | 1 |
| 4 | What is the duration of normal labour显示文摘 | Blix E Kumle M Oian P | 2008 | Tidsskr Nor Laegeforen2008，12，： | 1 |
| 5 | Predominance of a single genotype of Mycobacterium tuberculosis in countries of east Asia显示文摘 | Van Soolingen D Oian L De Haas P | 1995 | J Clin Microbiol1995，33，12： | 1 |
| 6 | Imaging and analyzing the elasticity of vascular smooth muscle cells by atomic force acoustic micro- scope 显示文摘 | Zhang B Cheng Q Chen M Yao W G Oian M L Hu B | 2012 | Ultrasound in Medicine and Biology2012，38，8： | 1 |
| 7 | Effects of implant diameter, insertion depth, and loading angle on stress/strain fields in implant/jawbone systems finite element analysis 显示文摘 | Oian L Todo M Matsushita Y | 2008 | Int J Oral Maxillofac Implants2008，24，5： | 1 |
| 8 | Spectroscopic Properties of Er3+ -doped Na2O-Sb2O3-B2O3-SiO2 Glasses显示文摘 | Oian Q Wang Y Zhang Q Y | 2008 | J Non-Crys Solids2008，354，1： | 1 |
| 9 | Diagnostic accu racy of CT-guided transthoracic needle biopsy for soli tary pulmonary nodules显示文摘 | Wen Yang Wen KuiSun Oian Li | 2015 | PLoS One2015，10，6： | 1 |
| 10 | Formal query languages for secure relational databases显示文摘 | Smith K Oian X | 1994 | ACM Transac Datab Syst1994，19，04： | 1 |
| 11 | Fuzzy neural network modeling of material properties显示文摘 | Oian Hancheng Xia Bocai Li Shangzheng | 2002 | Journal of Materials Processing Technology2002，122，： | 1 |
| 12 | Molecular epide- miology of chicken anemia virus in commercial farms in China显示文摘 | Eltahir Y M Oian K Qin A J | 2011 | Viro J2011，8，： | 1 |
| 13 | Identifying risk factors for recurrent cesarean scar pregnancy: a case-control study显示文摘 | Oian Z D Guo Q Y Huang L L | 2014 | Fertil Steril2014，102，1： | 1 |
| 14 | Fear of childbirth, women's preference for cesarean section and childhood abuse: a longitudinal study显示文摘 | Lukasse M Vangen S Oian P | 2011 | Acta Obstet Gynecol Scand2011，90，1： | 1 |
| 15 | Determination of Avermectin B1 in Biological Samples by Immunoaffinity Column Cleanup and Liquid Chromatography with UV Detection显示文摘 | Li J Oian C | 1996 | J AOAC1996，79，5： | 1 |
| 16 | Load transfer and deformation mechanisms in carbon nanotube-polystyrene composites显示文摘 | Oian D Dickey E C Andrews R | 2000 | Applied Physics Letters2000，76，： | 1 |
| 17 | Behavior of steel tube-reinforced concrete composite walls subjected to high axial force and cyclic loading 显示文摘 | Oian J R Jiang Z Ji X D | 2012 | Engineering Structures2012，36，3： | 1 |
| 18 | Oedema- preventing mechanisms in subcutaneous tissue of normal pregnant women显示文摘 | Oian P Maltau JM Noddeland H | 1985 | Br J Obstet Gynaecol1985，92，11： | 1 |
| 19 | Calculated capillary hydrostatic pressure in normal pregnancy and preeclampsia显示文摘 | Oian P Mahau JM | 1987 | Am J ObstetGynecol1987，157，1： | 1 |
| 20 | Enhanced platelet release reaction related to arterial plasma adrendline and blood pressure in preeclampsia 显示文摘 | Young GS Greenbanm BH | 1996 | Br J Obstet Gynaecol1996，103，2： | 1 |
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