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| 1 | Genome-wide association study identifies loci for body composition and structural soundness traits in pigs显示文摘 | Fan B Onteru SK Du Z-Q | 2011 | PloS one2011，6，14： | 1 |
| 2 | Ge- nome-wide association study identifies loci for bodycomposition and structural soundness traits in pigs 显示文摘 | FAN B ONTERU S K GARRICK D J | 2011 | PLoSOne2011，6，14： | 1 |
| 3 | Large-scale association study for structural soundness and leg locomotion traits in thepig显示文摘 | FAN B ONTERU S K MOTE B K | 2009 | Genetics Selection Evolution2009，41，3： | 1 |
| 4 | Genome-wide association study identifies loci for body compo-sition and structural soundness traits in pigs 显示文摘 | FAN B ONTERU S K DU Z Q | 2011 | PLoS ONE2011，6，： | 1 |
| 5 | Genome- wide association study identifies Loci for body compo- sition and structural soundness traits in pigs 显示文摘 | FAN B ONTERU S K DU Z Q | 2011 | PLoS ONE2011，6，14： | 1 |
| 6 | The role of gene discovery, QTL analyses and gene expression in reproductive traits in the pig 显示文摘 | ONTERU S K ROSS J W ROTHSCHILD M F | 2009 | Soc Reprod Fertil Suppl2009，66，： | 1 |
| 7 | Whole--genome association analyses for li- fetime reproductive traits in the pig显示文摘 | Onteru S | 2011 | J Anita Sci2011，89，4： | 1 |
| 8 | A gene-based SNP linkage map for pacific white shrimp,Litopenaeus vannamei显示文摘 | Du Z Q Ciobanu D C Onteru S K Gorbach D Mileham A J Jaramillo G Rothschild M F | | 0，，03： | 1 |
| 9 | The role of gene discovery,QTL analyses and gene expression in reproductive traits in the pig显示文摘 | Onteru S K Ross J W Rothschild M F | | 0，，： | 1 |
| 10 | Large-scale association study for strucrural soundness and leg locomotion traits in the pig显示文摘 | Fan B Onteru SK Mote BE | | 0，，： | 1 |
| 11 | A whole-genome association study for pig reprodective traits 显示文摘 | Onteru S K Fan B Du Z Q | 2012 | Anim Genet2012，43，1： | 1 |
| 12 | Genome-wide association study identifies Loci for body composition and structural soundness traits in pigs显示文摘 | FAN B ONTERU S K DU Z Q | 2011 | PLoS One2011，6，14： | 1 |
| 13 | A clinically relevant combination treatment with doxorubicin and cyclophosphamide does not induce hepatotoxicity in C57BL/6J mice显示文摘Background and aims:Chronic exposure to chemotherapeutics can lead to severe adverse events including hepatotoxicity.A combination chemotherapy regimen of doxorubicin(DOX)and cyclophos-phamide(CPS)is employed in treatment of several cancers such as leukemia,lymphoma,and breast cancer.It is not well understood whether a combination therapy with DOX and CPS can induce hepa-totoxicity.We therefore sought to determine whether co-administration of DOX and CPS at their clini-cally relevant doses and frequency results in hepatotoxicity.Methods:Male C57BL/6J mice received one intraperitoneal injection of saline or DOX-2 mg/kg and CPS-50 mg/kg once a week for 4 weeks.After the treatment period,liver histology and various serum bio-markers of hepatotoxicity were assessed.Results:Co-treatment with DOX and CPS did not alter the serum levels of alanine aminotransferase(ALT),alkaline phosphatase(ALP),bilirubin,albumin,globulin,or total protein.Similarly,co-administration of DOX and CPS did not result in a noticeable change in liver histology.However,it was notable that the concomitant treatment with DOX and CPS resulted in a significant increase in serum levels of aspartate aminotransferase(AST).Elevated serum AST levels were also associated with increased serum creatinine kinase(CK)levels,suggesting that the elevated serum AST levels are likely due to muscle injury following the co-administration of DOX and CPS.Conclusions:Taken together,our results,for the first time,suggest that co-administration of DOX and CPS,at their clinically relevant doses and frequency does not induce a significant hepatotoxicity in the mice. | Satyanarayana R Pondugula Julia M Salamat Kodye L Abbott Patrick C Flannery Mohammed Majrashi Mohammed Almaghrabi Manoj Govindarajulu Sindhu Ramesh Maninder Sandey Suneel K Onterue Chen-Che J Huang Yoshimi Iwaki Kristina Gill Natasha Narayanan Edwin McElroy Darshini Desai Rishi Nadar Timothy Moore Muralikrishnan Dhanasekaran | 2021 | Liver Research2021，5，4： | 1 |
| 14 | A gene-based SNP linkage map for pacific white shrimp, Litopenaeus van- namei显示文摘 | Du Z Q Ciobanu D C Onteru S K | 2010 | Anim Genet2010，41，3： | 1 |
| 15 | Whole genome association studies of residual feed intake and related traits in the pig显示文摘 | Onteru S K Gorbach D M Young J M | 2013 | PLoS One2013，8，61： | 1 |
| 16 | Genome-wide association study identifies Loci for body composition and structural soundness traits in pigs显示文摘 | Fan B Onteru S K Du Z Q | 2011 | PLoS One2011，6，14： | 1 |
| 17 | Whole -genome association analyses for lifetime reproductive traits in the pig 显示文摘 | Onteru S K Fan B Nikkila M T et a/ | 2011 | Journal of Animal Science2011，89，4： | 1 |
| 18 | A whole-genome association study for pig reproductive traits显示文摘 | Onteru S K Fan B Du Z Q | 2011 | Anim Genet2011，43，1： | 1 |
| 19 | Whole genome association studies of residual feed intake and related traits in the pig 显示文摘 | Onteru S K Gorbach D M Young J M | 2013 | PLoS One2013，8，61： | 1 |
| 20 | Genome-wide asso- ciation study identifies loci for body composition and structural soundness traits in pigs 显示文摘 | Fan B Onteru S K Du Z Q et at | 2011 | PLoS One2011，6，14： | 1 |
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