| 3 | Oxygen Nanoshuttles for Tumor Oxygenation and Enhanced Cancer Treatment显示文摘Tumor hypoxia is one of the hostile tumor micro-environment characteristics occurring in solid tumors.This feature is closely related to tumor progression and can negatively impair the effec-tiveness of cancer therapeutics.Recently,various strategies have been developed that enable effi-cient tumor oxygenation,not only enhancing tre-atment outcome of oxygen-consuming cancer therapeutics such as radiotherapy and photody-namic therapy,but also reversing the immunosup-pressive tumor microenvironment to promote cancer immunotherapy.This review focuses on the latest progress in design and fabrication of inno-vative tumor-targeted oxygen nanoshuttles that attenuate tumor hypoxia and enhance cancer therapy.Future perspectives for clinical translation of tumor-targeted oxygen nanoshuttles will be fur-ther discussed. | Liangzhu Feng Oshra Betzer Danlei Tao Tamar Sadan Rachela Popovtzer Zhuang Liu | 2019 | CCS Chemistry2019，1，3： | 0 |
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