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| 1 | Rescue associating liver partition and portal vein ligation for staged hepatectomy after portal embolization: Our experience and literature review显示文摘AIM To report a single-center experience in rescue associating liver partition and portal vein ligation for staged hepatectomy(ALPPS), after failure of previous portal embolization. We also performed a literature review.METHODS Between January 2014 and December 2015, every patient who underwent a rescue ALPPS procedure in Toulouse Rangueil University Hospital, France, was included. Every patient included had a project of major hepatectomy and a previous portal vein embolization(PVE) with insufficient future liver remnant to body weight ratio after the procedure. The ALPPS procedure was performed in two steps(ALPPS-1 and ALPPS-2), separated by an interval phase. ALPPS-2 was done within 7 to 9 d after ALPPS-1. To estimate the FLR, a computed tomography scan examination was performed 3 to 6 wk after the PVE procedure and 6 to 8 d after ALPPS-1. A transcystic stent was placed during ALPPS-1 and remained opened duringthe interval phase, in order to avoid biliary complications. Postoperative liver failure was defined using the 50-50 criteria. Postoperative complications were assessed according to the Dindo-Clavien Classification.RESULTS From January 2014 to December 2015, 7 patients underwent a rescue ALPPS procedure. Median FLR before PVE, ALPPS-1 and ALPPS-2 were respectively 263 cc(221-380), 450 cc(372-506), and 660 cc(575-776). Median FLR/BWR before PVE, ALPPS-1 and ALPPS-2 were respectively 0.4%(0.3-0.5), 0.6%(0.5-0.8), and 1%(0.8-1.2). Median volume growth of FLR was 69%(18-92) after PVE, and 45%(36-82) after ALPPS-1. The combination of PVE and ALPPS induced a growth of median initial FLR of +408 cc(254-513), leading to an increase of +149%(68-199). After ALPPS-2, 4 patients had stage Ⅰ-Ⅱ complications. Three patients had more severe complications(one stage Ⅲ, one stage Ⅳ and one death due to bowel perforation). Two patients suffered from postoperative liver failure according to the 50/50 criteria. None of our patients developed any biliary complication during the ALPPS procedure.CONCLUSION Rescue ALPPS may be an alternative after unsuccessful PVE and could allow previously unresectable patients to reach surgery. Biliary drainage seems to reduce biliary complications. | Charlotte Maulat Antoine Philis Bérénice Charriere Fatima-Zohra Mokrane Rosine Guimbaud Philippe Otal Bertrand Suc Fabrice Muscari | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 2 | Early plasmapheresis and rituximab for acute humoral rejection after ABO-compatible liver transplantation显示文摘Acute humoral rejection (AHR) is uncommon after ABO-compatible liver transplantation. Herein, we report two cases of AHR treated with plasmapheresis and rituximab in two ABO-compatible liver-transplant patients with preformed anti-human leukocyte antigen donor-specif ic antibodies. Patient 1 experienced a biopsy-proven AHR at day 10 post-transplant. She was treated by steroid pulses, and OKT3. Because of persisting signs of biopsy-proven AHR at day 26, she was treated by plasmapheresis and rituximab. Liver enzyme levels did not improve, and she died on day 41. Patient 2 experienced a biopsy-proven AHR on day 10 post-transplant. She was treated by steroid pulses, plasmapheresis, and rituximab. Liver enzymes returned to within normal range 18 d after diagnosis. Liver biopsies, at 3 and 9 mo post-transplant, showed complete resolution of AHR. We conclude that plasmapheresis should be started as soon as AHR is diagnosed, and be associated with a B-cell depleting agent. Rituximab may be considered as a first-line therapy. | Nassim Kamar Laurence Lavayssière Fabrice Muscari Janick Selves Céline Guilbeau-Frugier Isabelle Cardeau Laure Esposito Olivier Cointault Marie Béatrice Nogier Jean Marie Peron Philippe Otal Marylise Fort Lionel Rostaing | 2009 | World Journal of Gastroenterology2009，15，27： | 6 |
| 3 | Macroporous polyester-covered stent in an experimental abdominal aortic aneurysm model显示文摘 | Soula P Janne d'Othee B Otal P | | 0，，04： | 1 |
| 4 | In vitro evaluation of a new rotational thrombectomy device:the Straub Rotarex catheter显示文摘 | Zana K Otal P Fornet B | 2001 | Cardiovasc Intervent Radiol2001，24，5： | 1 |
| 5 | Aortoduodenal fistula after endovascular stent-graft of an abdominal aortic aneurysm显示文摘 | Janne d'Othee B Soula P Otal P | 2000 | J Vasc Surg2000，31，11： | 1 |
| 6 | Endoscopic ultrasound and magnetic resonance cholangiopancreatography in patients with idiopathic acute pancreatitis显示文摘 | Thevenot A Bournet B Otal P | 2013 | Dig Dis Sci2013，58，8： | 1 |
| 7 | Highly reliable energy-saving mac for wireless body sensor networks in healthcare systems 显示文摘 | Otal B Alonso L Verikoukis C | 2009 | IEEE Journal on Selected Areas in Communications2009，27，4： | 1 |
| 8 | PAHs in the Fraser River basin: a critical appraisal PAH ratios as indicators of PAH source and composition显示文摘 | YUNKER M B MACDONALD R W VINGARZAN R otal | 2002 | Organic Geochemistry2002，33，4： | 1 |
| 9 | Highly reliable energysaving MAC for wireless body sensor networks in healthcare systems显示文摘 | OTAL B ALONSO L VERIKOUKIS C | | 0，，04： | 1 |
| 10 | Phase II /III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a pediatric oncology group trial显示文摘 | GOORIN A M HARRIS M B BERNSTEIN M otal | 2002 | J C/in Oncol2002，20，2： | 1 |
| 11 | Regulation of brain glucosetransporters by glucose and oxygen deprivation显示文摘 | Bruekner B A Ammini C V Otal M P | 1999 | Metabolism1999，48，4： | 1 |
| 12 | Locally Graded Minimal Non CC-groups are p-groups 显示文摘 | Hartley B Otal J Penn J M | 1991 | Arch Math1991，57，3： | 1 |
| 13 | Imaging and endovascular treatment of renal artery stenosis in the diabetic patient显示文摘 | Otal P Janne D'Othee B Chabbert V | 2000 | Diabetes Metab2000，26，： | 1 |
| 14 | Mefformin therapy decreases hyperandrogenism and hyperinsulinaemia in women with polycystic ovary syndrome显示文摘 | Kolodzieczyk B Duleba A J Spaezynski RZ otal | 2000 | Fertil Steril2000，73，6： | 1 |
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