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| 1 | Differential diagnosis of obsessive-compulsive symptoms from delusions in schizophrenia: A phenomenological approach显示文摘Several studies suggest increased prevalence-rates of obsessive-compulsive symptoms(OCS) and even of obsessive-compulsive disorder(OCD) in patients with schizophrenic disorders. Moreover, it has been recently proposed the existence of a distinct diagnostic subgroup of schizo-obsessive disorder. However, the further investigation of the OCS or OCD-schizophrenia diagnostic comorbidity presupposes the accurate clinical differential diagnosis of obsessions and compulsions from delusions and repetitive delusional behaviours, respectively. In turn, this could be facilitated by a careful comparative examination of the phenomenological features of typical obsessions/compulsions and delusions/repetitive delusional behaviours, respectively. Thiswas precisely the primary aim of the present investigation. Our examination included seven features of obsessions/delusions(source of origin and sense of ownership of the thought, conviction, consistency with one's belief-system, awareness of its inaccuracy, awareness of its symptomatic nature, resistance, and emotional impact) and five features of repetitive behaviours(aim of repetitive behaviours, awareness of their inappropriateness, awareness of their symptomatic nature, and their immediate effect on underlying thought, and their emotional impact). Several of these clinical features, if properly and empathically investigated, can help discriminate obsessions and compulsive rituals from delusions and delusional repetitive behaviours, respectively, in patients with schizophrenic disorders. We comment on the results of our examination as well as on those of another recent similar investigation. Moreover, we also address several still controversial issues, such as the nature of insight, the diagnostic status of poor insight in OCD, the conceptualization and differential diagnosis of compulsions from other categories of repetitive behaviours, as well as the diagnostic weight assigned to compulsions in contemporary psychiatric diagnostic systems. We stress the importance of the feature of mental reflexivity for understanding the nature of insight and the ambiguous diagnostic status of poor insight in OCD which may be either a marker of the chronicity of obsessions, or a marker of their delusionality. Furthermore, we criticize two major shortcomings of contemporary psychiatric diagnostic systems(DSM-IV, DSM-V, ICD-10) in their criteria or guidelines for the diagnosis of OCD or OCS: first, the diagnostic parity between obsessions and compulsions and, second, the inadequate conceptualization of compulsions. We argue that these shortcomings might artificially inflate the clinical prevalence of OC symptoms in the course of schizophrenic disorders. Still, contrary to a recent proposal, we do not exclude on purely a priori grounds the possibility of a concurrence of genuine obsessions along with delusions in patients with schizophrenia. | Panagiotis Oulis George Konstantakopoulos Lefteris Lykouras Panayiota G Michalopoulou | 2013 | World Journal of Psychiatry2013，3，3： | 2 |
| 2 | The rela- tionship between insight and theory of mind in schizophrenia 显示文摘 | George Konstantakopoulos G Ploumpidis D Oulis P | 2014 | Schizophrenia Research2014，152，1： | 1 |
| 3 | Phase Ⅰ trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AHl11585 in breast cancer patients显示文摘 | Kenny LM Coombes RC Oulie I | 2008 | J Nucl Med2008，49，： | 1 |
| 4 | Euler-Lagrange coupling with damping effects: application to slamming prob- lems显示文摘 | AQUELET N $OULI M OLOVSSON L | 2006 | Computer Methods in Applied Mechanics and Engin- eering2006，195，13： | 1 |
| 5 | The effect of impurity ions in molten salt KNO3 on ion-exchange and strengthening of glass显示文摘 | Zhang X C Ouli H Cengzuo X | 1986 | Journal of Non-crystalline Solids1986，80，1： | 1 |
| 6 | Phase I trial of the positron-emitting Arg-Gly-Asp(RGD) peptide radioligand ^18F-AH111585 in breast cancer patients显示文摘 | Kenny L M Coombes R C Oulie I | 2008 | J Nucl Med2008，49，6： | 1 |
| 7 | Phase I trial of the positron-emitting Arg-Gly-Asp(RGD)peptide radioligand 18F-AH111585 in breast cancer patients显示文摘 | Kenny LM Coomhes RC Oulie I | | 0，，： | 1 |
| 8 | The effect of impu-rity ions in molten saltKNO3 on ion-exchange and strengthening of glass显示文摘 | ZHANG Xiangchen HE Ouli XU Zengzuo | 1986 | J Non-Cryst Solids1986，80，： | 1 |
| 9 | Phase I trial of the posi-tron-emitting Arg-Gly-Asp ( RGD ) peptide radioligand 18 F-AH111585 in breast cancer patients 显示文摘 | Kenny LM Coombes RC Oulie I | 2008 | J Nucl Med2008，49，6： | 1 |
| 10 | A Srchomology inding sequence on the Cterminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibrob last grow th factor receptor stimulation 显示文摘 | L ao DH Chandram ouli S Yusoff P | 2006 | J B iol Chem2006，281，29： | 1 |
| 11 | Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AHl11585 in breast cancer patients 显示文摘 | Kenny LM Coombes RC Oulie J | 2008 | J Nucl Med2008，49，6： | 1 |
| 12 | Five-factor model of schizophrenic psychopathology:how valid is it?显示文摘 | Lykouras L Oulis P Psarros K | 2000 | Eur Arch Psychiatry Clin Neurosci2000，250，： | 1 |
| 13 | A Src homology 3 binding sequence on the C terminus of Sprouty2 is necessary for inhibtion of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation显示文摘 | Lao DH Chandram ouli S Yusoff P | 2006 | J Biol Chem2006，281，29： | 1 |
| 14 | Preoperative imaging of the carotid bifurcation, current trends显示文摘 | ATHANAS OULIS C A PLOMARITOGLOU A | 2000 | Int Angiol2000，19，1： | 1 |
| 15 | Du-loxetine-induced cutaneous adverse reaction 显示文摘 | OULIS P MASDRAKIS VG KARAKATSANIS NA | 2008 | J Clin Psycho-pharmacol2008，28，1： | 1 |
| 16 | Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand ^18F-AHl11585 in breast cancer patients显示文摘 | Kenny L M Coombes R C Oulie I | 2008 | J Nuel Med2008，49，6： | 1 |
| 17 | A case of se- vere toluene with drawal syndrome treated with clonazepam 显示文摘 | Kouzoupis A V Konstantakopoulos G Oulis P | 2010 | J Neuropsychiatry Clin Neurosci2010，22，1： | 1 |
| 18 | Reversal of increased arterial stiffness in severely depressed women after 6-week antidepressant treatment显示文摘 | Oulis P Kouzoupis A Kyrkou K | 2010 | J Affect Disord2010，122，12： | 1 |
| 19 | Adjunctive low-dose amisulpride in motor conversion disorder显示文摘 | Oulis P Kokras N Papadimitriou GN | 2009 | Clin Neuropharmacol2009，32，6： | 1 |
| 20 | Dental injuries of permanent teeth treated in private practice in Athens显示文摘 | Oulis C J Berdouses ED | 1996 | Endod Dent Traumatol1996，12，2： | 1 |
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