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| 1 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017，6，1： | 6 |
| 2 | Real-time nonlinear finite element analysis for surgical simulation using graphics processing units显示文摘 | Taylor ZA Cheng M Ourselin S | 2007 | Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv2007，10，1： | 1 |
| 3 | Automated genera- tion of curved planar reformations from MR images of the spine 显示文摘 | VRTOVEC T OURSELIN S GOMES L | 2007 | Physics in Medicine and Biology2007，52，10： | 1 |
| 4 | Block matching: A general framework to improve ro- bustness of rigid registration of medical images显示文摘 | OURSELIN S ROCHE A PRIMA S | 2000 | Lecture Notes in Computer Science2000，1935，： | 1 |
| 5 | Reconstrcting a 3D structure from serial histological sections显示文摘 | Ourselin S Roche A Subsol X | 2001 | Image Vision Comput2001，19，12： | 1 |
| 6 | High-speed nonlinear finite element analysis for surgical simulation usinggraphics processing units显示文摘 | Taylor Z Cheng M Ourselin S | 2008 | IEEE Transactions on Medical Imaging2008，27，： | 1 |
| 7 | On modelling of anisotropic viscoelasticity for soft tissue simulation: Numerical solution and GPU execution 显示文摘 | Z A Taylor O Comas M Cheng J Passenger D J Hawkes D Atkinson S Ourselin | 2009 | Medical Image Analysis (S1361-8415)2009，13，2： | 1 |
| 8 | Computation of the mid-sagittal plane in 3D images of the brain 显示文摘 | Prima S Ourselin S Ayache N | 2002 | IEEE Trans Med Imaging2002，21，： | 1 |
| 9 | Patterns of cortical thinning in the language variants of frontotemporal lobar degeneration显示文摘 | J D. Rohrer J D. Warren M Modat G R. Ridgway A Douiri M N. Rossor S Ourselin N C. Fox | 2009 | Neurology2009，，18： | 1 |
| 10 | Reconstructing a 3D structure from serial histological sections 显示文摘 | Ourselin S Roche A Subsol G | 2001 | Image Vision Comput2001，19，12： | 1 |
| 11 | A Novel Method for Implementation of Frameless StereoEEG in Epilepsy Surgery显示文摘 | Mark Nowell Roman Rodionov Beate Diehl Tim Wehner Gergely Zombori Jane Kinghorn Sebastien Ourselin John Duncan Anna Miserocchi Andrew McEvoy | 2014 | Neurosurgery2014，，： | 1 |
| 12 | The effect of motion correction on pharmacokinetic parameter estimation in dynamic-contrast-enhanced MRI显示文摘 | A Melbourne J Hipwell M Modat T Mertzanidou H Huisman S Ourselin D J Hawkes | 2011 | Physics in Medicine and Biology2011，，24： | 1 |
| 13 | On modelling of Anisotropic Viscoelasticity for Soft Tissue Simulation: Numerical Solution and GPU Execution 显示文摘 | Z A Taylor O Comas M Cheng J Passenger D J Hawkas D Atkinson S Ourselin | 2009 | Medical Image Analysis (S1361-8415)2009，13，2： | 1 |
| 14 | High-speed nonlinear finite element analysis for surgical simulation using graphics processing units显示文摘 | Taylor Z A Cheng M Ourselin S | | 0，，05： | 1 |
| 15 | A reduced order finite element algorithm for surgical simulation显示文摘 | Taylor Z A Ourselin S Crozier S | | 0，，： | 1 |
| 16 | 立体脑电图颅内电极植入的准确性:系统评价和Meta分析显示文摘立体脑电图(SEEG)是一种将电极植入大脑以帮助确定致痫灶的操作。它是在非侵入性检查不能确定致痫灶的情况下,对耐药性局灶性癫痫患者进行明确的癫痫手术之前进行的。这项操作的主要风险是出血,发生率为1%~2%,可能原因是电极放置不准确,或者计划的植入电极损伤了在术前血管成像中未检测到的血管。推荐的电极植入技术包括:使用立体定向框架、无框架影像导航系统、机器人导航系统和定制的患者固定装置。研究参照系统评价和Meta分析推荐报告条目(Preferred reporting items for systematic reviews and Metaanalysis,PRISMA),结构化搜索Pub Med、Embase和Cochrane数据库,纳入的研究涉及:(1)SEEG电极植入作为术前工作的一部分;(2)针对耐药性局灶性癫痫患者;(3)提供准确数据。数据库检索出326篇文章,删除重复和非英语语言的研究后,筛选出293篇文章。应用纳入和排除标准后,最终有15项研究纳入定性和定量分析。利用随机效应的元分析和技术分层,最终总结出SEEG电极植入的准确性。发表有关SEEG植入技术的准确性文献有限。目前并没有比较不同SEEG植入技术的前瞻性对照临床试验。在已确定的研究之间存在显著的系统异质性,妨碍了各项技术之间有意义的比较。最近引进的机器人导航系统被认为提供了一种更精确的植入方法,但支持证据仅限于3级。在将新技术引入进行广泛临床应用之前,有必要通过良好设计、方法合理的研究将新技术与以前的'金标准'进行比较。 | Vejay N.Vakharia Rachel Sparks Aidan G.O'Keeffe 李维 高慧 慕洁 Roman Rodionov Anna Miserocchi Andrew McEvoy Sebastien Ourselin John Duncan | 2018 | 癫痫杂志2018，4，5： | 0 |
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