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| 1 | Effect of cervical spondylosis on vertebral arterial flow and its association with vertigo显示文摘 | Ilkay Koray Bayrak Dilek Durmus Ayse Oytun Bayrak Baris Diren Ferhan Canturk | 2009 | Clinical Rheumatology2009，，1： | 1 |
| 2 | Intramedullary nailing supplemented with Poller screws for proximal tibial fractures显示文摘 | Oytun I Marangoz S | 2013 | J Orthup Surg (Hong Kong)2013，21，1： | 1 |
| 3 | Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients显示文摘 | Oytun Portakal Ozay Ozkaya Mine Erden Inal | 2000 | Clinical Biochemistry2000，33，4： | 1 |
| 4 | Effects of pentoxifylline and coenzyme Q10 in hepatic ischemia/reperfusion injury显示文摘 | Oytun Portakal Mine Inal-Erden | 1999 | Clinical Biochemistry1999，32，6： | 1 |
| 5 | Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients 显示文摘 | Oytun Portakal Ozay Ozkaya Mine Erden Inal | 2000 | Clinical Biochemistry2000，33，4： | 1 |
| 6 | Effects of pentoxifylline and coenzyme Q10 in hepatic ischemia/ reperfusion injury 显示文摘 | Oytun Portakal Mine ìnal-Erden | 1999 | Clinical Biochemistry1999，32，6： | 1 |
| 7 | The Role of Ankaferd Blood Stopper and Oxytocin as Potential Therapeutic Agents in Endometriosis:A Rat Model显示文摘To evaluate the potential effect of Ankaferd Blood Stopper(ABS)and oxytocin(OT)in an experimental endometriosis model,18 female Sprague Dawley rats were used in this study.The animals were divided randomly into three groups after surgical induction of endometriosis:group 1:control group(isotonic NaCl,1 mL/kg/day,intramuscular,n=6);group 2:OT group(OT,80 U/kg/day,intramuscular,n=6);group 3:ABS group(ABS,1.5 mL/kg/day,intraperitoneal,n=6).Each group was treated for four weeks(two times per week).Volumes of endometriotic explants were measured in biopsy samples for histopathological analysis.Vascular endothelial growth factor(VEGF),monocyte chemotactic protein-1(MCP-1),and tumour necrosis factor(TNF-α)levels were measured in plasma and peritoneal fluid.Endometriotic explant volumes were significantly decreased after OT administration(P<0.0001).The epithelial score was significantly decreased in both treatment groups compared to the control group(P<0.05).TUNEL immunohistochemistry showed more apoptotic changes in the endometriosis foci(gland epithelium and surrounding tissue)in the OT group than in the control group(P<0.05).The levels of VEGF,MCP-1,and TNF-αwere significantly reduced in the OT group(P<0.05),whereas no significant changes in protein levels were found in the ABS-applied group.The results indicate that OT has greater potential as a therapeutic agent in experimentally induced peritoneal endometriosis,where ABS,which is a VEGF modulator,appears to act through different mechanisms to show its palliative effects on a rat model of peritoneal endometriosis. | Ismet Hortu Gokay Ozceltik Elif Karadadas Oytun Erbas Gurkan Yigitturk Murat Ulukus | 2020 | Current Medical Science2020，40，3： | 1 |
| 8 | Exenatide promotes regeneration of injured rat sciatic nerve显示文摘Damage to peripheral nerves results in partial or complete dysfunction. After peripheral nerve injuries, a full functional recovery usually cannot be achieved despite the standard surgical repairs. Neurotrophic factors and growth factors stimulate axonal growth and support the viability of nerve cells. The objective of this study is to investigate the neurotrophic effect of exenatide(glucagon like peptide-1 analog) in a rat sciatic nerve neurotmesis model. We injected 10 μg/d exenatide for 12 weeks in the experimental group(n = 12) and 0.1 m L/d saline for 12 weeks in the control group(n = 12). We evaluated nerve regeneration by conducting electrophysiological and motor functional tests. Histological changes were evaluated at weeks 1, 3, 6, and 9. Nerve regeneration was monitored using stereomicroscopy. The electrophysiological and motor functions in rats treated with exenatide were improved at 12 weeks after surgery. Histological examination revealed a significant increase in the number of axons in injured sciatic nerve following exenatide treatment confirmed by stereomicroscopy. In an experimentally induced neurotmesis model in rats, exenatide had a positive effect on nerve regeneration evidenced by electromyography, functional motor tests, histological and stereomicroscopic findings. | Ersin Kuyucu Bilal Gumus Oytun Erbas Fatih Oltulu Arslan Bora | 2017 | Neural Regeneration Research2017，12，4： | 0 |
| 9 | Short term protective effect of digitoxin in sepsis-induced acute lung injury显示文摘Purpose:Digitoxin is a cardiac glycoside used in the treatment of heart failure.Inspired by its known antiinflammatory effect,this study aims to investigate the effect of digoxin in a sepsis model and to bring to light its effect and underlying mechanism in acute lung injury(ALI).Method:28 wistar albino rats were divided into 4 groups.Sepsis model is performed by the feces intraperitoneal-injection procedure(FIP).Results:TNF-a,CRP,IL-6,IL 1-Beta,lactic acid,and MDA values were significantly decreased in the FIP+digitoxin group compared to the FIP+Saline group.When the same groups were examined,histological improvements such as decrease in alveolar inflammation and decrease in septal thickening in the digitoxin group and thorax CT were found to be significantly higher in the Hounsfield unit digitoxin group compared to the Saline group.Conclusion:Digitoxin has shown biochemical improvement in sepsis with all known mechanisms of action,and healing effects in both computerized tomography and histology in the lung. | EJDER SAYLAV BORA MÜMIN ALPER ERDOĞAN BAHATTINÖZKUL İBRAHIM HALIL SEVER İBRAHIM SÖĞÜT CANAN HÜRDAĞ OYTUN ERBAŞ | 2022 | BIOCELL2022，46，2： | 0 |
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