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| 1 | Relationship between LYVE-1, VEGFR-3 and CD44 gene expressions and lymphatic metastasis in gastric cancer显示文摘AIM: To investigate the expression levels of lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), vascular endothelial growth factor receptor-3 (VEGFR-3) and CD44 genes and the relationship between their lev- els and clinicopathological parameters in gastric cancer.METHODS: Tissue samples were obtained from 33 patients (8 females) with gastric cancer. mRNA levels of LYVE-1, VEGFR-3 and CD44 in normal and tumor tissues were quantitatively measured using real time polymerase chain reaction. The results were correlated with lymph node metastasis, histological type and differentiation of the tumor, T-stage, and presence of vascular, perineural and lymphatic invasions. The distribution of molecules in the tissue was evaluated using immunohistochemistry. RESULTS: LYVE-1, CD44 and VEGFR-3 gene expression levels were significantly higher in gastric cancer than in normal tissue. While there was no correlation between gene expressions and clinicopathologic fea- tures such as histologic type, differentiation and stage, gene expression levels were found to be increased in conjunction with positive lymph node/total lymph node ratio and the presence of perineural invasion. A significant correlation was also found between LYVE-1 and CD44 over-expressions and perineural invasion and lymph node positivity in gastric cancers. When the dis- tribution of LYVE-1 antibody-stained lymphatic vessels in tissue was evaluated, lymphatic vessels were located intra-tumorally in 13% and peri-tumorally in 27% of the patients. Moreover, lymph node metastases were also positive in all patients with LYVE-1-staining. CONCLUSION: LYVE-1, VEGFR-3 and CD44 all play an important role in lymphangiogenesis, invasion and metastasis. LYVE-1 is a perfectly reliable lymphatic vessel marker and useful for immunohistochemistry. | Fusun Ozmen M Mahir Ozmen Evren Ozdemir Munevver Moran Selda Sekin Dicle Guc Ergun Karaagaoglu Emin Kansu | 2011 | World Journal of Gastroenterology2011，17，27： | 27 |
| 2 | Internal biliary fistula due to cholelithiasis:A single-centre experience显示文摘AIM: To discuss about the perioperative problems encountered in patients with internal biliary fistula (IBF) caused by cholelithiasis. METHODS: In our hospital, 4 130 cholecystectomies were carried out for symptomatic cholelithiasis from January 2000 to March 2004 and only 12 patients were diagnosed with IBF. The perioperative data of these 12 IBF patients were analyzed retrospectively. RESULTS: The incidence of IBF due to cholelithiasis was nearly 0.3%. The mean age was 57 years. Most of the patients presented with non-specific complaints. Only two patients were considered to have IBF when gallstone ileus was observed during the investigations. Nine patients underwent emergency laparotomy with a pre-operative diagnosis of acute abdomen. In the remaining three patients, elective laparoscopic cholecystectomy was converted to open surgery after identification of IBF. Ten patients had cholecystoduodenal fistula and two patients had cholecystocholedochal fistula. The mean hospital stay was 13 d. Two wound infections, three bile leakages and three mortalities were observed. CONCLUSION: Cholecystectomy has to be performed in early stage in the patients who were diagnosed as cholelithiasis to prevent the complications like IBF which is seen rarely. Suspicion of IBF should be kept in mind, especially in the case of difficult dissection during cholecystectomy and attention should be paid in order to prevent iatrogenic injuries. | Arife Polat Duzgun Mehmet Mahir Ozmen Mehmet Vasfi Ozer Faruk Coskun | 2007 | World Journal of Gastroenterology2007，13，34： | 15 |
| 3 | Is obstructive sleep apnea syndrome a risk factor for pulmonary thromboembolism?显示文摘 | Kezban Ozmen Suner AliNihat Annakkaya Umran Toru Talha Dumlu Ege Gulec Balbay Peri Arbak Leyla Yilmaz Aydin Hasan Suner | 2012 | Chinese Medical Journal2012，，20： | 9 |
| 4 | Solid amine sorbents for CO_(2) capture by chemical adsorption: A review显示文摘Amines are well-known for their reversible reactions with CO_(2),which make them ideal for CO_(2) capture from several gas streams,including flue gas.In this respect,selective CO_(2) absorption by aqueous alkanolamines is the most mature technology but the process is energy intensive and has also corrosion problems.Both disadvantages can be diminished to a certain extent by chemical adsorption of CO_(2) selectively.The most important element of the chemical adsorption of CO_(2) involves the design and development of a suitable adsorbent which consist of a porous support onto which an amine is attached or immobilized.Such an adsorbent is often called as solid amine sorbent.This review covers solid amine-based studies which are developed and published in recent years.First,the review examines several different types of porous support materials,namely,three mesoporous silica(MCM-41,SBA-15 and KIT-6)and two polymeric supports(PMMA and PS)for CO_(2) adsorption.Emphasis is given to the synthesis,modifications and characterizations-such as BET and PXRD data-of them.Amination of these supports to obtain a solid amine sorbent through impregnation or grafting is reviewed comparatively.Focus is given to the adsorption mechanisms,material characteristics,and synthesis methods which are discussed in detail.Significant amount of original data are also presented which makes this review unique.Finally,relevant CO_(2) adsorption(or equilibrium)capacity data,and cyclic adsorption/desorption performance and stability of important classes of solid amine sorbents are critically reviewed.These include severa PEI or TEPA impregnated adsorbents and APTES-grafted systems. | Elif ErdalÜnveren Bahar Ozmen Monkul S¸erife Sarıoglan Nesrin Karademir Erdogan Alper | 2017 | Petroleum2017，3，1： | 8 |
| 5 | Predictors of poor outcome in gastrointestinal bleeding in emergency department显示文摘AIM: To determine the prognostic risk factors of gastrointestinal bleeding in emergency department cases.METHODS: The trial was a retrospective single-center study involving 600 patients over 18-years-old and carried out with approval by the Institutional Ethics Committee. Patient data included demographic characteristics, symptoms at admission, past medical history, vital signs, laboratory results, endoscopy and colonoscopy results, length of hospital stay, need of intensive care unit(ICU) admission, and mortality. Mortality rate was the principal endpoint of the study, while duration of hospital stay, required interventional treatment, and admission to the ICU were secondary endpoints.RESULTS: The mean age of patients was 61.92-yearsold. Among the 600 total patients, 363(60.5%) underwent upper gastrointestinal endoscopy and the most frequent diagnoses were duodenal ulcer(19.2%) and gastric ulcer(12.8%). One-hundred-and-fifteen(19.2%) patients required endoscopic treatment, 20(3.3%) required surgical treatment, and 5(0.8%) required angiographic embolization. The mean length of hospital stay was 5.21 ± 5.85 d. The mortality rate was 6.3%. The ICU admission rate was 5.3%. Patients with syncope, higher blood glucose levels, and coronary artery disease had significantly higher ICU admission rates(P = 0.029, P = 0.043, and P = 0.002, respectively). Patients with low thrombocyte levels, high creatinine, high international normalized ratio, and high serum transaminase levels had significantly longer hospital stay(P = 0.02, P = 0.001, P = 0.019, and P = 0.005, respectively). Patients who died had significantly higher serum blood urea nitrogen and creatinine levels(P = 0.016 and P = 0.038), and significantly lower mean blood pressure and oxygen saturation(P = 0.004 and P = 0.049). Malignancy and low Glasgow coma scale(GCS) were independent predictive factors of mortality.CONCLUSION: Prognostic factors for gastrointestinal bleeding in emergency room cases are malignancy, hypotension on admission, low GCS, and impaired kidney function. | Ender Kaya Mehmet Ali Karaca Deniz Aldemir M Mahir Ozmen | 2016 | World Journal of Gastroenterology2016，22，16： | 4 |
| 6 | Retinal vessel diameters and their correlation with retinal nerve fiber layer thickness in patients with pseudoexfoliation syndrome显示文摘AIM: To compare retinal artery-vein diameters(RAVDs)of patients with pseudoexfoliation(PSX) syndrome with healthy controls and investigate the correlations between retinal nerve fiber layer(RNFL) thickness parameters and RAVDs.METHODS: Seventeen eyes with PSX and 17 eyes of age-matched controls were included in the study. All participants underwent routine ophthalmological examination, Humphrey visual field and RNFL examination by using Stratus OCT. Retinal images were obtained by using a retinal camera(Topcon 501X).RAVDs were measured from inferior nasal, inferior temporal, superior nasal and superior temporal arcuates by using IMAGEnet software. Superior, inferior, nasal,temporal and average RNFL thicknesses were recorded.RAVDs and RNFL parameters in groups and correlations were analyzed by Mann-Whitney U and Spearmann correlation tests.RESULTS: Only inferior quadrant and average RNFL thickness were detected thinner in the PSX group compared with control group(P =0.009, P =0.038,respectively). No statistically significant difference regarding RAVDs was found between two groups.CONCLUSION: RAVDs seems to be comparable in the PSX and control group. RNFL is thinner in the inferior quadrant in the PSX group. RNFL thickness and RAVDs show significant correlations in both groups. This correlation doesn't seem to be specific to PSX. | Mehmet Cuneyt Ozmen Zeynep Aktas Burcin Kepez Yildiz Murat Hasanreisoglu Berati Hasanreisoglu | 2015 | International Journal of Ophthalmology(English edition)2015，8，2： | 3 |
| 7 | Impact of laparoscopic surgery on bladder and sexual function after total mesorectal excision for rectal cancer显示文摘 | Oktar Asoglu Tugba Matlim Hasan Karanlik Murat Atar Mahmut Muslumanoglu Yersu Kapran Abdullah Igci Vahit Ozmen Mustafa Kecer Mesut Parlak | 2009 | Surgical Endoscopy2009，，2： | 2 |
| 8 | YALIKAVAK精品酒店,博德鲁姆-穆拉,土耳其显示文摘这座40间客房的精品酒店位于博德鲁姆的Yalikavak,美丽的爱琴海沿岸。设计通过在不同层高上交错布置遮蔽、半遮蔽和露天开放区域,营造出呼应场所地形、主导风向和景观的连续空间。 | Suna Birsen-Otay Sevim Aslan Ipek Yurekli Deniz Aslan Arda Inceoglu Kemal Ozmen Ilker Aksoy Ceren Hancioglu Esin Gumus Gunseli Dolluk 项琳斐 | 2010 | 世界建筑2010，，7： | 2 |
| 9 | Carvacrol partially reverses symptoms of diabetes in STZ-induced diabetic rats显示文摘 | Gokhan Bayramoglu Hakan Senturk Aysegul Bayramoglu Mustafa Uyanoglu Suat Colak Ayse Ozmen Durdane Kolankaya | 2014 | Cytotechnology2014，，2： | 2 |
| 10 | The knowledge and attitudes of breast self-examination and mammography in a group of women in a rural area in western Turkey 显示文摘 | Dundar PE Ozmen D Ozttirk B | 2006 | BMC Cancer2006，24，6： | 1 |
| 11 | Staging laparoscopy for gastric cancer, surgical laparoscopy显示文摘 | Ozmen M Mahir MD MS | 2003 | Endoscopy & Percu taneous Techniques2003，13，4： | 1 |
| 12 | Bone mineral density in children with neurofibromatosis l显示文摘 | Yilmaz K Ozmen M Goksan SB | 2007 | Acta Padiatrica2007，96，8： | 1 |
| 13 | Association between homocysteinemia and renal function in patients with type 2 diatetes mellitus显示文摘 | Billigin Ozmen Dilek Ozmen Nevbahar Turgan | 2002 | Annals of Clinical Laboratory Science2002，32，10： | 1 |
| 14 | Impact of gradual blood flow increase on ischemia-reperfusion injury in the rat cremaster microcirculationmodel 显示文摘 | Ozmen S Ayhan S Demir Y | 2008 | J Plast Reconstr Aesthet Surg2008，61，8： | 1 |
| 15 | 64-MDCT pulmonary angiography and CT venography in the diagnosis of thromboem bolic disease显示文摘 | Nazaroglu H Ozmen C A Akay H O | 2009 | AJR2009，192，3： | 1 |
| 16 | Effects of astatin group drug, pravastain, on the insulin reistance in patients With metabolior syndrome 显示文摘 | Guclu F Ozmen B Hekimsoy Z | 2004 | Biomeb Pharlnacother2004，10，： | 1 |
| 17 | Does the complication rate increase in laparoscopic cholecystectomy for acute cholecystitis 显示文摘 | Asoglu O Ozmen V Karanlik H | 2004 | Laparoendosc Adv Surg Tech A2004，14，2： | 1 |
| 18 | Effects of a statin group drug pravastation on the insulin resistance with metabolic syndrome显示文摘 | Guclu F Ozmen B Hekimsoy Z | 2004 | Biomed Pharmacother2004，10，： | 1 |
| 19 | Lenssuperoxide dismutase and catalase activities in diabetic cataract显示文摘 | Ozmen B Ozmen D Erkin E Habif S Giiner L Bayindir O | 2002 | Clin Biochem2002，35，1： | 1 |
| 20 | Factors influencing mortal- ity in traumatic rupture of diaphragm 显示文摘 | Diazgon AP Ozmen MM Saylam B el al | 2008 | Ulus Travma Acil Cerrahi Derg2008，14，： | 1 |
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