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| 1 | China National Medical Products Administration approval summary:anlotinib for the treatment of advanced non-small cell lung cancer after two lines of chemotherapy显示文摘Background:On May 8,2018,the China National Medical Products Administration(NMPA)approved anlotinib,an orally administered anti-angiogenesis inhibitor,for the treatment of patients with advanced non-small cell lung can-cer(NSCLC)who have progressed after treatment with two or more lines of prior systemic chemotherapy.Main body of the abstract:China NMPA reviewed and inspected a regional double-blinded,placebo-controlled,Phase III trial comparing the overall survival(OS)of NSCLC patients between the anlotinib and placebo arms.A total of 437 patients were randomized(2:1)to receive either anlotinib(n=294)or placebo(n=143)once daily on a 2-week on and 1-week off schedule.Patients with epidermal growth factor receptor(EGFR)or activating anaplastic lymphoma kinase(ALK)genomic tumor aberrations should have disease progression on NMPA-approved therapy.Anlotinib is the first NMPA-approved drug for patients with advanced NSCLC who have progressed on at least two lines of prior systemic chemotherapies in China.The approval was based on a statistically and clinically significant improvement in median OS with anlotinib(9.46 months)compared with placebo[6.37 months;hazard ratio(HR])=0.70,95%confidence interval(CI)=0.55-0.89;two-sided log-rank P=0.002].The confirmed objective response rate(ORR)was 9.2%in the anlotinib arm and 0.7%in the placebo arm.The median duration of response(DoR)was 4.83 months,with a 95%CI of 3.31-6.97 months.The toxicity profile of anlotinib was consistent with that of known anti-angiogenesis inhibitors.Common adverse drug reactions(ADRs)in anlotinib-treated patients included hypertension(67.4%),hand-foot syndrome(43.9%),hemoptysis(14.0%),thyroid stimulating hormone(TSH)elevation(46.6%),and corrected QT interval(QTc)prolongation(26.2%).Short conclusion:Anlotinib demonstrated a clinically significant OS prolongation as a novel therapeutic option for advanced or metastatic NSCLC following at least two lines of chemotherapy. | Ming Zhou Xiaoyuan Chen Hong Zhang Lin Xia Xin Tong Limin Zou Ruimin Hao Jianhong Pan Xiao Zhao Dongmei Chen Yuanyuan Song Yueli Qi Ling Tang Zhifang Liu Rong Gao Yuankai Shi Zhimin Yang | 2019 | Cancer Communications2019，39，1： | 35 |
| 2 | Hygroscopic growth of aerosol scattering coefficient:A comparative analysis between urban and suburban sites at winter in Beijing显示文摘A humidity controlled inlet system was developed to measure the hygroscopic growth of aerosol scattering coefficient in conjunction with nephelometry at an urban site of Chinese Academy of Meteorological Sciences (CAMS) in Beijing and a rural site at Shangdianzi Regional Background Air Pollution Monitoring Station (SDZ) outside Beijing during winter, from December 2005 to January 2006. Measurements were carried out at a wavelength of 525 nm with an Ecotech M9003 nephelometer. The hygroscopic growth function (or factor) of the aerosol scattering coefficient f(RH) increased continuously with increasing relative humidity (RH) and showed no obvious 'step-like' deliquescent behavior at both sites during the experiment. The average growth factor f(RH) at the SDZ site could reach 1.5 when RH increased from less than 40% to 92%, and to 2.1 at the CAMS site when RH increased from less than 40% to 93%. The average hygroscopic growth factor at a relative humidity of 80%, f(RH = 80 ± 1%), was found to be about 1.26 ± 0.15 at CAMS and 1.24 ± 0.11 at SDZ. Further analysis indicated that under relatively polluted conditions, the average hygroscopic growth factor was higher at the CAMS site than that at the SDZ site. However, under relatively clean air conditions, the difference between the two sites was small, showing a hygroscopic growth behavior similar to those of burning biomass or blowing dust. These results reflected the different characteristics of aerosol types at the two sites. | Peng Yan Xiaole Pan Jie Tang Xiuji Zhou Renjian Zhang Limin Zeng | 2009 | Particuology2009，7，1： | 30 |
| 3 | Ultrasensitive skin‐like wearable optical sensors based on glass micro/nanofibers显示文摘Electronic skin,a class of wearable electronic sensors that mimic the functionalities of human skin,has made remarkable success in applications including health monitoring,human-machine interaction and electronic-biological interfaces.While electronic skin continues to achieve higher sensitivity and faster response,its ultimate performance is fundamentally limited by the nature of low-frequency AC currents.Herein,highly sensitive skin-like wearable optical sensors are demonstrated by embedding glass micro/nanofibers(MNFs)in thin layers of polydimethylsiloxane(PDMS).Enabled by the transition from guided modes into radiation modes of the waveguiding MNFs upon external stimuli,the skin-like optical sensors show ultrahigh sensitivity(1870 k·Pa^-1),low detection limit(7 mPa)and fast response(10μs)for pressure sensing,significantly exceeding the performance metrics of state-of-the-art electronic skins.Electromagnetic interference(EMI)-free detection of high-frequency vibrations,wrist pulse and human voice are realized.Moreover,a five-sensor optical data glove and a 2×2-MNF tactile sensor are demonstrated.These initial results pave the way toward a new category of optical devices ranging from ultrasensitive wearable sensors to optical skins. | Lei Zhang Jing Pan Zhang Zhang Hao Wu Ni Yao Dawei Cai Yingxin Xu Jin Zhang Guofei Sun Liqiang Wang Weidong Geng Wenguang Jin Wei Fang Dawei Di Limin Tong | 2020 | Opto-Electronic Advances2020，3，3： | 12 |
| 4 | Functionalized polymer nanofibers: a versatile platform for manipulating light at the nanoscale显示文摘As an organic optical fiber with a diameter comparable to or less than the wavelength of light,polymer nanofibers have been attracting increasing attention as a platform for manipulating light at the nanoscale.A variety of applications for polymer optical nanofibers,including waveguides,light sources and sensors,have been reported in recent years.In this article,the recent progress in the field of polymer optical nanofibers is reviewed in terms of their fabrication,characterization and applications.In particular,we focus on functionalized polymer nanofibers doped with functional materials,such as dye molecules,noble metal nanoparticles,quantum dots and rare earth ions,which greatly expand their capabilities of generating,propagating,converting and modulating light at the nanoscale. | Pan Wang Yipei Wang Limin Tong | 2013 | Light(Science & Applications)2013，2，1： | 9 |
| 5 | 中国国家药品监督管理局批准安罗替尼用于经两种系统化疗后疾病进展的晚期非小细胞肺癌的治疗显示文摘背景2018年5月8日,中国国家药品监督管理局(National Medical Products Administration,NMPA)批准了小分子多靶点抗血管抑制剂盐酸安罗替尼,用于既往经过至少两种系统化疗后疾病进展的晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者的治疗。概要中国NMPA审查了一项随机双盲、安慰剂对照的III期临床试验,该临床试验的主要终点为总生存期(overall survival,OS)。试验共纳入437例患者随机分组(2∶1)接受安罗替尼(n=294)或安慰剂(n=143)治疗,每日1次,连服2周,停药1周。表皮生长因子受体(epidermal growth factor receptor,EGFR)基因敏感突变或间变性淋巴瘤激酶(activating anaplasticlymphomakinase,ALK)阳性的患者须经过NMPA已批准的药物治疗后出现疾病进展。安罗替尼为中国NMPA批准的用于治疗既往经过两种及以上系统化疗后疾病进展的晚期NSCLC患者的首个药物。安罗替尼组的中位OS(9.46个月)较安慰剂组[6.37个月;风险比(hazard ratio,HR)=0.70,95%置信区间(confidence Interval,CI):0.55–0.89;双侧log-rank P=0.002]显著延长。安罗替尼组的客观缓解率(objective responserate,ORR)为9.2%,安慰剂组为0.7%。安罗替尼组的中位缓解持续时间(durationofresponse,DoR)为4.83个月,95%CI为3.31–6.97个月。安罗替尼的常见不良反应(adverse drug reactions,ADRs)包括高血压(67.4%)、手足综合征(43.9%)、咳血(14.0%)、促甲状腺激素(thyroid stimulating hormone,TSH)升高(46.6%)、心电图QT间期(corrected QT Interval,QTc)延长(26.2%)。结论安罗替尼显著延长了患者的OS,可作为经二线及以上化疗后晚期或转移性非小细胞肺癌的一种新的治疗方案。 | Ming Zhou Xiaoyuan Chen Hong Zhang Lin Xia Xin Tong Limin Zou Ruimin Hao Jianhong Pan Xiao Zhao Dongmei Chen Yuanyuan Song Yueli Qi Ling Tang Zhifang Liu Rong Gao Yuankai Shi Zhimin Yang | 2019 | 癌症2019，38，12： | 7 |
| 6 | Optical Micro/Nano Fibers Enabled Smart Textiles for Human-Machine Interface显示文摘Wearable human-machine interface(HMI)is an advanced technology that has a wide range of applications from robotics to augmented/virtual reality(AR/VR).In this study,an optically driven wearable human-interactive smart textile is proposed by integrating a polydimethylsiloxane(PDMS)patch embedded with optical micro/nanofibers(MNF)array with a piece of textiles.Enabled by the highly sensitive pressure dependent bending loss of MNF,the smart textile shows high sensitivity(65.5 kPa^(−1))and fast response(25 ms)for touch sensing.Benefiting from the warp and weft structure of the textile,the optical smart textile can feel slight finger slip along the MNF.Furthermore,machine learning is utilized to classify the touch manners,achieving a recognition accuracy as high as 98.1%.As a proof-of-concept,a remote-control robotic hand and a smart interactive doll are demonstrated based on the optical smart textile.This optical smart textile represents an ideal HMI for AR/VR and robotics applications. | Shuqi Ma Xiaoyu Wang Pan Li Ni Yao Jianliang Xiao Haitao Liu Zhang Zhang Longteng Yu Guangming Tao Xiong Li Limin Tong Lei Zhang | 2022 | Advanced Fiber Materials2022，4，5： | 5 |
| 7 | Boosting the photodynamic therapy efficiency with a mitochondria-targeted nanophotosensitizer显示文摘Photodynamic therapy (PDT) is an attractive clinical technique for cancer treatment. However, the poor solubility and weak cellular internalization of the molecule-photosensitizers, as well as the exceedingly short lifetime and limited diffusion distance of the generated reactive oxygen species (ROS) in cytoplasm directly restricted the therapeutic efficiency of conventional PDT. In this study, we proposed a facile strategy for improving PDT of cancer based on a mitochondria-targeted nanophotosensitizer. The molecule-photosensitizer chlorin e6 was covalently attached on the internal and external surfaces of the mesoporous silica nanoparticles. Then, the triphenylphosphonium was anchored on the nanoparticles for selectively targeting mitochondria. When irradiated with laser, the nanophotosensitizer can generate a large amount of ROS in mitochondria, thus causing the mitochondrial dysfunction and irreversible cell apoptosis. In vitro and in vivo studies demonstrated that the nanophotosensitizer could boost the treatment efficiency against cancer cells and xenograft tumor models. | Limin Yang Peng Gao Yuanlei Huang Xiao Lu Qian Chang Wei Pan Na Li Bo Tang | 2019 | Chinese Chemical Letters2019，30，6： | 4 |
| 8 | Lipopolysaccharide induced intestinal epithelial injury:a novel organoids-based model for sepsis in vitro显示文摘Background: Advances in organoid culture technology have provided a greater understanding of disease pathogenesis, which has been rarely studied in sepsis before. We aim to establish a suitable organoids-based intestinal injury model for sepsis.Methods: Stable passaged organoids were constructed and pre-treated with lipopolysaccharide (LPS) to mimic sepsis-induced intestinal injury. The LPS-induced sepsis model was used as a reference. We used quantitative real-time polymerase chain reaction to evaluate the RNA levels of inflammatory factors and antimicrobial peptides. Enzyme-linked immunosorbent assay was used to evaluate the protein levels, hematoxylin and eosin staining was used to evaluate the pathology of the small intestine of mice, and immunohistochemistry and immunofluorescence were used to evaluate the intestinal epithelial barrier function. Perkin Elmer OperettaTM was used to obtain high-resolution images of three-dimensional organoids.Results: An LPS concentration >150 μg/mL after 24 h was identified to cause organoid growth restriction. The fluorescence intensity of zonula occludens-1 and occludins at LPS concentrations >100 μg/mL decreased significantly after 24 h. After LPS stimulation for 8 h, the RNA expression levels of interleukin (IL)-1α, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, IL-6, and regenerating islet-derived protein 3 alpha, beta, and gamma increased. These results resembled those of intestinal epithelial layer alterations in a mouse sepsis model. For IL-10, the RNA expression level increased only when the LPS level >200 μg/mL for 24 h.Conclusions: This study provides the primary intestinalin vitro model to study the effects of LPS-induced intestinal injury resembling sepsis. This model provides a platform for immune associated mechanism exploration and effective drug screening. | Sisi Huang Sheng Zhang Limin Chen Xiaojun Pan Zhenliang Wen Yizhu Chen Lidi Zhang Jiao Liu Dechang Chen | 2022 | Chinese Medical Journal2022，135，18： | 3 |
| 9 | Mid-infrared chalcogenide microfiber knot resonators显示文摘A novel type of mid-IR microresonator,the chalcogenide glass(ChG)microfiber knot resonator(MKR),is demonstrated,showing easy fabrication,fiber-compatible features,resonance tunability,and high robustness.ChG micro fibers with typical diameters around 3μm are taper-drawn from As2S3 glass fibers and assembled into MKRs in liquid without surface damage.The measured Q factor of a typical 824μm diameter ChG MKR is about 2.84×104 at the wavelength of 4469.14 nm.The free spectral range(FSR)of the MKR can be tuned from2.0 nm(28.4 GHz)to 9.6 nm(135.9 GHz)by tightening the knot structure in liquid.Benefitting from the high thermal expansion coefficient of As2S3 glass,the MKR exhibits a thermal tuning rate of 110 pm·℃^-1 at the resonance peak.When embedded in polymethyl methacrylate(PMMA)film,a 551μm diameter MKR retains a Q factor of 1.1×10^4.The ChG MKRs demonstrated here are highly promising for resonator-based optical technologies and applications in the mid-IR spectral range. | YU XIE DAWEI CAI HAO WU JING PAN NING ZHOU CHENGUANG XIN SHAOLIANG YU PAN WANG XIAOSHUN JIANG JIANRONG QIU XIN GUO LIMIN TONG | 2020 | Photonics Research2020，8，4： | 3 |
| 10 | Controllable preparation and microwave absorption properties of shape anisotropic Fe_(3)O_(4) nanobelts显示文摘To substantially prevent electromagnetic threatens,microwave absorbing materials(MAMs)are required to eliminate surplus electromagnetic waves.As a typical MAM,Fe_(3)O_(4) particles with complex permittivity and permeability have been widely applied due to the coexistence of magnetic loss and dielectric loss.However,the necessary high mass fraction significantly limited its applications,thus Fe_(3)O_(4) nanostructures have been extensively investigated to overcome this problem.In this work,uniform Fe_(3)O_(4) nanobelts were prepared by electrospinning and two-step thermal treatment.By controlling the composition and viscosity of the electrospinning precursor solution,Fe_(3)O_(4) nanobelts with tunable lateral sizes(200 nme1 mm)were obtained.The samples with low content(only 16.7 wt%)Fe_(3)O_(4) exhibited wide maximum effective absorbing bandwidths(EAB)over 3 GHz,and Fe_(3)O_(4) nanobelts with smaller lateral sizes showed a maximum EAB of 4.93 GHz.Meanwhile,Fe_(3)O_(4) nanobelts with smaller lateral sizes presented superior reflection loss properties,the lowest reflection loss reached-53.93 dB at 10.10 GHz,while the maximum EAB was up to 2.98 GHz.The excellent microwave reflection loss of Fe_(3)O_(4) nanobelts was contributed to the enhanced synergistic effect of magnetic loss,dielectric loss,and impedance matching,originated from the hierarchically cross-linked networks and shape anisotropies.This study could broaden the practical applications of magnetic absorbers,and provided an approach for the development of shape anisotropic magnetic materials. | Jialiang Pan Rujing Zhang Jun Ling Min Wang Zechen Li Zhen Zhen Limin He Hongwei Zhu | 2021 | Journal of Materiomics2021，7，5： | 3 |
| 11 | Non-dormant Axillary Bud 1 regulates axillary bud outgrowth in sorghum显示文摘Tillering contributes to grain yield and plant architecture and therefore is an agronomically important trait in sorghum(Sorghum bicolor).Here,we identified and functionally characterized a mutant of the Nondormant Axillary Bud 1(NAB1)gene from an ethyl methanesulfonate-mutagenized sorghum population.The nab1 mutants have increased tillering and reduced plant height.Map-based cloning revealed that NAB1encodes a carotenoid-cleavage dioxygenase 7(CCD7)orthologous to rice(Oryza sativa)HIGH-TILLERING DWARF1/DWARF17 and Arabidopsis thaliana MORE AXILLARY BRANCHING 3.NAB1 is primarily expressed in axillary nodes and tiller bases and NAB1 localizes to chloroplasts.The nab1 mutation causes outgrowth of basal axillary buds;removing these non-dormant basal axillary buds restored the wild-type phenotype.The tillering of nab1 plants was completely suppressed by exogenous application of the synthetic strigolactone analog GR24.Moreover,the nab1plants had no detectable strigolactones and displayed stronger polar auxin transport than wild-type plants.Finally,RNA-seq showed that the expression of genes involved in multiple processes,including auxin-related genes,was significantly altered in nab1.These results suggest that NAB1 functions in strigolactone biosynthesis and the regulation of shoot branching via an interaction with auxin transport. | Jun Chen Limin Zhang Mengjiao Zhu Lijie Han Ya Lv Yishan Liu Pan Li Haichun Jing Hongwei Cai | 2018 | Journal of Integrative Plant Biology2018，60，10： | 3 |
| 12 | Upregulation of SIRT1 by 17β-estradiol depends on ubiquitin-proteasome degradation of PPAR-γ mediated by NEDD4-1显示文摘17β-estradiol (E2) treatment of cells results in an upregulation of SIRT1 and a down-regulation of PPARγ. The decrease in PPARγ expression is mediated by increased degradation of PPARγ. Here we report that PPARγ is ubiquitinated by HECT E3 ubiquitin ligase NEDD4-1 and degraded, along with PPARγ, in response to E2 stimulation. The PPARγ interacts with ubiquitin ligase NEDD4-1 through a conserved PPXY-WW binding motif. The WW3 domain in NEDD4-1 is critical for binding to PPARΓ. NEDD4-1 overexpression leads to PPARγ ubiquitination and reduced expression of PPARγ. Conversely, knockdown of NEDD4-1 by specific siRNAs abolishes PPARΓ ubiquitination. These data indicate that NEDD4-1 is the E3 ubiquitin ligase responsible for PPARγ ubiquitination. Here, we show that NEDD4-1 delays cellular senescence by degrading PPARΓ expression. Taken together, our data show that E2 could upregulate SIRT1 expression via promoting the PPARΓ ubiquitination-proteasome degradation pathway to delay the process of cell senescence. | Limin Han Pan Wang Ganye Zhao Hui Wang Meng Wang Jun Chen Tanjun Tong | 2013 | Protein & Cell2013，4，4： | 3 |
| 13 | Single optical microfiber enabled tactile sensor for simultaneous temperature and pressure measurement显示文摘The ability to sense heat and touch is essential for healthcare,robotics,and human–machine interfaces.By taking advantage of the engineerable waveguiding properties,we design and fabricate a flexible optical microfiber sensor for simultaneous temperature and pressure measurement based on theoretical calculation.The sensor exhibits a high temperature sensitivity of 1.2 nm/℃ by measuring the shift of a high-order mode cutoff wavelength in the short-wavelength range.In the case of pressure sensing,the sensor shows a sensitivity of 4.5%per kilopascal with a fast temporal frequency response of 1000 Hz owing to the strong evanescent wave guided outside the microfiber.The cross talk is negligible because the temperature and pressure signals are measured at different wavelengths based on different mechanisms.The properties of fast temporal response,high temperature,and pressure sensitivity enable the sensor for real-time skin temperature and wrist pulse measurements,which is critical to the accurate analysis of pulse waveforms.We believe the sensor will have great potential in wearable optical devices ranging from healthcare to humanoid robots. | NI YAO XIAOYU WANG SHUQI MA XINGDA SONG SHAN WANG ZHANGXING SHI JING PAN SHIPENG WANG JIANLIANG XIAO HAITAO LIU LONGTENG YU YAO TANG ZHANG ZHANG XIONG LI WEI FANG LEI ZHANG LIMIN TONG | 2022 | Photonics Research2022，10，9： | 2 |
| 14 | Highly sensitive and fast response strain sensor based on evanescently coupled micro/nanofibers显示文摘Flexible strain sensors play an important role in electronic skins,wearable medical devices,and advanced robots.Herein,a highly sensitive and fast response optical strain sensor with two evanescently coupled optical micro/nanofibers(MNFs)embedded in a polydimethylsiloxane(PDMS)film is proposed.The strain sensor exhibits a gauge factor as high as 64.5 for strain≤0.5%and a strain resolution of 0.0012%which corresponds to elongation of 120 nm on a 1 cm long device.As a proof-of-concept,highly sensitive fingertip pulse measurement is realized.The properties of fast temporal frequency response up to 30 kHz and a pressure sensitivity of 102 kPa^(−1) enable the sensor for sound detection.Such versatile sensor could be of great use in physiological signal monitoring,voice recognition and micro-displacement detection. | Wen Yu Ni Yao Jing Pan Wei Fang Xiong Li Limin Tong Lei Zhang | 2022 | Opto-Electronic Advances2022，5，9： | 2 |
| 15 | Formation and Optical Properties of ZnO:ZnFe_(2)O_(4) Superlattice Microwires显示文摘Pure ZnO hexagonal microwires and Fe(Ⅲ)-doped ZnO microwires(MWs)with a novel rectangular cross section were synthesized in a confined chamber by a convenient one-step thermal evaporation method.An oriented attachment mechanism is consistent with a vapor-solid growth process.Photoluminescence(PL)and Raman spectroscopy of the Fe(Ⅲ)-doped ZnO MWs and in situ spectral mappings indicate a quasi-periodic distribution of Fe(Ⅲ)along a one-dimensional(1-D)superlattice ZnO:ZnFe_(2)O_(4) wire,while PL mapping shows the presence of optical multicavities and related multimodes.The PL spectra at room temperature show weak near-edge doublets(376 nm and 383 nm)and a broad band(450-650 nm)composed of strong discrete lines,due to a 1-D photonic crystal structure.Such a 1-D coupled optical cavity material may find many applications in future photonic and spintronic devices. | Yun Li Guozhang Dai Chunjiao Zhou Qinglin Zhang Qiang Wan Limin Fu Jianping Zhang Ruibin Liu Chuanbao Cao Anlian Pan Yunhong Zhang Bingsuo Zou | 2010 | Nano Research2010，3，5： | 2 |
| 16 | A Multifunctional Airfow Sensor Enabled by Optical Micro/nanofber显示文摘Fiber-optic anemometers have attracted an increasing attention over the past decade owing to their high sensitivity,wide dynamic range,low power consumption,and immunity to electromagnetic interference.However,expensive instruments may limit their practical applications.Herein,a new type of airfow sensor based on optical micro/nanofber(MNF)is proposed and realized.The sensing element is a fexible polydimethylsiloxane(PDMS)cantilever embedded with a U-shaped MNF.Upon exposure to airfow,the induced defection of the cantilever results in a bending-dependent transmittance variation of the embedded MNF.The performance of the sensor can be engineered by tuning the cantilever thickness and/or the MNF diameter.When four cantilevers are arranged in two orthogonal directions,the transmittance of each cantilever will be dependent on both fow speed and direction.By analysing the output signals of the four cantilevers,omnidirectional airfow with fow speed within 15 m/s were experimentally measured.In addition,a variety of voice and respiratory signals can be monitored and distinguished in real-time using an optimized cantilever with a resolution of 0.012 m/s,presenting great potential for health monitoring applications. | Zhang Zhang Yuran Kang Ni Yao Jing Pan Wen Yu Yao Tang Yue Xu Liqiang Wang Lei Zhang Limin Tong | 2021 | Advanced Fiber Materials2021，3，6： | 2 |
| 17 | Modeling diurnal variation of ground thermal radiance images using energy balance model and endmember composing technique显示文摘Modeling and analyzing dynamic changes of land thermal radiance scenes play an important role in thermal remote sensing.In this paper,the diurnal variation of ground surface thermal scene is mainly discussed.Firstly,based on the land surface energy balance equation,the diurnal variation of land surface temperatures(LSTs) over bare land covers were simulated by an analytical thermal model with second harmonic terms,and the diurnal LST variation of vegetation canopy was simulated using the Cupid model.Secondly,normalized difference vegetation index(NDVI),normalized difference water index(NDWI),and ratio resident-area index(RRI) were used to evaluate the endmember abundance of four land cover types including vegetation,bare soil,impervious and water area,which were calculated from IKONOS visible and near infrared(VNIR) bands.Finally,the thermal radiance scenes at various times and view angles were modeled based on the linear-energy-mixing hypothesis.The results showed that the simulated daily LST variations for vegetated and bare surfaces are correlated with the measured values with a maximum standard deviation of 2.7°C,that land thermal radiant textures with high-resolution are restored from the linear-energy-mixing method,and that the information abundance of the scene are related to the distribution of land cover,the imaging time,and the view angle. | ZHAO LiMin GU XingFa YU Tao WAN Wei XIONG Pan XIE YanHua ZHANG Lun | 2012 | Science China(Technological Sciences)2012，55，11： | 2 |
| 18 | On-chip single-mode CdS nanowire laser显示文摘By integrating a free-standing cadmium sulfide(CdS)nanowire onto a silicon nitride(SiN)photonic chip,we demonstrate a highly compact on-chip single-mode CdS nanowire laser.The mode selection is realized using a Mach-Zehnder interferometer(MZI)structure.When the pumping intensity exceeds the lasing threshold of 4.9 kW/cm^(2),onchip single-mode lasing at ~518.9 nm is achieved with a linewidth of 0.1 nm and a side-mode suppression ratio of up to a factor of 20(13 dB).The output of the nanowire laser is channelled into an on-chip SiN waveguide with high efficiency(up to 58%)by evanescent coupling,and the directional coupling ratio between the two output ports can be varied from 90 to 10% by predesigning the coupling length of the SiN waveguide.Our results open new opportunities for both nanowire photonic devices and on-chip light sources and may pave the way towards a new category of hybrid nanolasers for chip-integrated applications. | Qingyang Bao Weijia Li Peizhen Xu Ming Zhang Daoxin Dai Pan Wang Xin Guo Limin Tong | 2020 | Light(Science & Applications)2020，9，1： | 1 |
| 19 | Modeling of nanoparticle-induced Rayleigh-Gans scattering for nanofiber optical sensing 显示文摘 | Shanshan Wang Xinyun Pan Limin Tong | 2007 | Opt Commun2007，276，2： | 1 |
| 20 | Synthesis and characterization of epoxy-acrylate composite latex 显示文摘 | PAN Guirong WU Limin ZHANG Zhuqing | 2002 | J Appl Polym Sci2002，83，： | 1 |
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