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| 1 | Ultrasensitive skin‐like wearable optical sensors based on glass micro/nanofibers显示文摘Electronic skin,a class of wearable electronic sensors that mimic the functionalities of human skin,has made remarkable success in applications including health monitoring,human-machine interaction and electronic-biological interfaces.While electronic skin continues to achieve higher sensitivity and faster response,its ultimate performance is fundamentally limited by the nature of low-frequency AC currents.Herein,highly sensitive skin-like wearable optical sensors are demonstrated by embedding glass micro/nanofibers(MNFs)in thin layers of polydimethylsiloxane(PDMS).Enabled by the transition from guided modes into radiation modes of the waveguiding MNFs upon external stimuli,the skin-like optical sensors show ultrahigh sensitivity(1870 k·Pa^-1),low detection limit(7 mPa)and fast response(10μs)for pressure sensing,significantly exceeding the performance metrics of state-of-the-art electronic skins.Electromagnetic interference(EMI)-free detection of high-frequency vibrations,wrist pulse and human voice are realized.Moreover,a five-sensor optical data glove and a 2×2-MNF tactile sensor are demonstrated.These initial results pave the way toward a new category of optical devices ranging from ultrasensitive wearable sensors to optical skins. | Lei Zhang Jing Pan Zhang Zhang Hao Wu Ni Yao Dawei Cai Yingxin Xu Jin Zhang Guofei Sun Liqiang Wang Weidong Geng Wenguang Jin Wei Fang Dawei Di Limin Tong | 2020 | Opto-Electronic Advances2020，3，3： | 12 |
| 2 | Discovery of a high-altitude ecotype and ancient lineage of Arabidopsis thaliana from Tibet显示文摘Arabidopsis thaliana(A.thaliana)has long been a model species for dicotyledon study,and was the first flowering plant to get its genome completed sequenced[1].Although most wild A.thaliana are collected in Europe,several studies have found a rapid A.thaliana west-east expansion from Central Asia[2].The Qinghai-Tibet Plateau(QTP)is close to Central Asia and known for its high alti- | Liyan Zeng Zhuoya Gu Min Xu Ning Zhao Weidong Zhu Takahiro Yonezawa Tianmeng Liu Lha Qiong Tashi Tersing Lingli Xu Yang Zhang Rongyan Xu Ningyu Sun Yanyan Huang Jiankun Lei Liang Zhang Feng Xie Fang Zhang Hongya Gu Yupeng Geng Masami Hasegawa Ziheng Yang M. James C. Crabbe Fan Chen Yang Zhong | 2017 | Science Bulletin2017，62，24： | 3 |
| 3 | Surface Charging Phenomena on HVDC Spacers for Compressed SF_(6) Insulation and Charge Tailoring Strategies显示文摘Surface flashover of spacers is a key factor limiting the application of HVDC GIS/GIL,while the charge accumula-tion on the surface of the spacer could have a potential adverse effect on the surface flashover voltage.This paper discusses the laws regarding distribution patterns of surface charges and the related mechanisms.The field-dependent property is discussed in detail to comprehensively illustrate the charge transport mecha-nism and explain the research differences regarding different surface charge patterns obtained by previous researchers.In addition,the main surface charge control methods for epoxy resin are summarized and discussed.The potential research directions of charge control methods and key points in manufacturing of spacers used in HVDC GIS/GIL are also explored. | Chuanyang Li Yuan Xu Chuanjie Lin Geng Chen Youping Tu Yao Zhou Zhipeng Lei Tao Han Simone Vincenzo Suraci Jian Wang Weidong Liu M.Tariq Nazir Shun He Andrea Cavallini Giovanni Mazzanti Davide Fabiani Jinliang He | 2020 | CSEE Journal of Power and Energy Systems2020，6，1： | 3 |
| 4 | Embedding visual cognition in 3D reconstruction from multi-view engineering drawings 显示文摘 | Weidong Geng Jingbin Wang Yiyang Zhang | 2002 | Computer-Aided Design2002，34，4： | 1 |
| 5 | Evaluation of the chemical profile from four germplasms sources of Pruni Semen using UHPLC-LTQ-Orbitrap-MS and multivariate analyses显示文摘Pruni Semen,the seed of several unique Prunus plants,is a traditional purgative herbal material.To determine the authentic sources of Pruni Semen,46 samples from four species were collected and analyzed.Ten compounds including multiflorin A(Mul A),a notable purative compound,were isolated and identified by chemical separation and nuclear magnetic resonance spectroscopy.Seventy-six communal components were identified by ultra-high performance liquid chromatography with linear ion trap-quadrupole Orbitrap mass spectrometry,and acetyl flavonoid glycosides were recognized as characteristic constituents.The flavonoids were distributed in the seed coat and cyanogenic glycosides in the kernel.Based on this,methods for identifying Pruni Semen from different sources were established using chemical fingerprinting,quantitative analysis of the eight principal compounds,hierarchical cluster analysis,principal component analysis,and orthogonal partial least squares discriminant analysis.The results showed that the samples were divided into two categories:one is the small seeds from Prunus humilis(Ph)and Prunus japonica(Pj),and the other is the big seeds from Prunus pedunculata(Pp)and Prunus triloba(Pt).The average content of Mul A was 3.02,6.93,0.40,and 0.29 mg/g,while the average content of amygdalin was 18.5,17.7,31.5,and 30.9 mg/g in Ph,Pj,Pp,and Pt,respectively.All the above information suggests that small seeds might be superior sources of Pruni Semen.This is the first comprehensive report on the identification of chemical components in Pruni Semen from different species. | Zihan Zhao Yue Liu Yushi Zhang Zeyu Geng Rina Su Lipeng Zhou Chao Han Zhanjun Wang Shuangcheng Ma Weidong Li | 2022 | Journal of Pharmaceutical Analysis2022，12，5： | 1 |
| 6 | Effect of porosity on mass transfer of gas absorption in a hollow fiber membrane contactor 显示文摘 | Zhang Weidong Hao Zisu Chen Geng | 2014 | Journal of Membrane Science2014，470，： | 1 |
| 7 | Methylation‐induced loss of miR ‐484 in microsatellite‐unstable colorectal cancer promotes both viability and IL ‐8 production via CD137L显示文摘 | Qian Mei Geng Xue Xiang Li Zhiqiang Wu Xiaolei Li Hongli Yan Mingzhou Guo Shuhan Sun Weidong Han | 2015 | J. Pathol2015，，2： | 1 |
| 8 | Synchro- nization regulation in a model of coupled neural masses 显示文摘 | MA Zhen ZHOU Weidong GENG Shujuan | 2013 | Biol Cybern2013，107，2： | 1 |
| 9 | A feasible SQP method for nonlinear programming显示文摘 | Zhu Zhibin Zhang Weidong Geng Zhenjie | 2010 | Applied Mathematics and Computation2010，，215： | 1 |
| 10 | Fully Automatic Liver Segmentation from Multi-slice Spiral Computed Tomographic Images显示文摘 | YUAN Xin YUAN Xin WANG Lei WANG Lei GENG Weidong GENG Weidong HU Hongjie HU Hongjie | 2009 | Chinese Journal of Electronics2009，18，4： | 1 |
| 11 | Study on Deformation Prediction of the Tunnel Surrounding Rocks Based on Non-equal Time-interval Grey Model显示文摘 | GENG Pengfei YANG Changmin GUO Weidong WANG Peng | 2014 | Applied Mechanics and Materials2014，，7： | 1 |
| 12 | LCoS Chip with Integrated 8-bit Gamma Compensated Digital Data Driver, 2005显示文摘 | Dai Yongping Geng Weidong Liu Yanyan Sun Zhonglin | 2005 | IEEE2005，，： | 1 |
| 13 | Complete debridement for treatment of thoracolumbar spinal tuberculosis: a clinical curative effect observation显示文摘 | Weidong Jin Qian Wang Zili Wang Guangqi Geng | 2014 | The Spine Journal2014，，6： | 1 |
| 14 | Embedding visual cognition in 3D reconstruction from multi-view engineering drawings显示文摘 | Weidong Geng Jingbin Wang Yiyang Zhang | 2002 | COMPUTER-AIDED DESIGN2002，34，4： | 1 |
| 15 | Acquisition of time-varying 3D foot shapes from video显示文摘The 3D scanning of time-varying objects based on multi-view geometry has been a hot topic in computer vision in recent years.This paper presents an active approach to acquiring 3D shapes of moving foot from multi-view video sequences based on the explicit marker points woven in socks.The reference 3D model of foot is firstly recovered from the starting frames in the multi-view video clips,and then the markers in each view are traced as a whole based on a continuous motion vector field built from the reference 3D model.The missing vertices in the candidate 3D model caused by self-occlusion,non-uniform illumination and random noises are reliably estimated and reconstructed in 3D space by minimizing the changes of differential features in 3D geometry of the reference model.The experimental results show that our method can robustly recover the 3D model of foot in complex background even if there is a relatively large movement between the adjacent frames,with an acceptable accuracy of the resulting 3D model. | GAO Fei WANG Qing GENG WeiDong PAN YunHe | 2011 | Science China(Information Sciences)2011，54，11： | 0 |
| 16 | Stent-assisted coiling of intracranial carotid ophthalmic segment aneurysm segment aneurysms:Long-term follow-up from a single center显示文摘Background:To evaluate the efficacy of stent-assisted coiling(SAC)for the treatment of carotid ophthalmic segment aneurysm segment aneurysms(OSAs)of the internal carotid artery(ICA)through detailed long-term follow-up of a large patient cohort.Methods:We retrospectively analyzed 88 consecutive patients with OSAs between January 2009 and January 2020 at our center.Angiographic results were evaluated using the modified Raymond grading system and clinical outcomes were evaluated using the mRS scale.The primary endpoints were major aneurysm recurrence and poor clinical outcomes for at least 18 months of follow-up.The patients were asked to attend clinical follow-up assessments and possibly undergo DSA or MR via telephone.Results:We enrolled 88 patients with 99 OSAs treated with coiling,of whom 76 were treated with SAC.The coiling procedures were successful in all 88 patients.Overall,complications occurred in 8 patients(9.1%).No procedure-related mortality was observed.67(76.1%)experienced immediate aneurysm occlusion at the end of the procedure.Long-term angiographic follow-up(18 months)was available in 45/88 aneurysms(51%)(average 18.7±5.2 months).Four patients continued their follow-up for 5 years after initial aneurysm treatment.After a clinical follow-up time of 28.7 months(range,12-51 months),85 patients(95.5%)achieved favorable clinical outcomes(mRS scores of 0-2).Conclusions:This study indicates that SAC treatment is a safe and effective therapeutic alternative for ruptured and unruptured OSAs.The procedural risks are low with relatively long-term effectiveness. | Wenquan Gu Geng Zhou Aizada Aldiyarova Tengyue Liu Yi Zhang Weidong Liu Lingping Meng Binxian Gu MingHua Li Ming Su Chen Su Aihua Liu Wu Wang | 2023 | Journal of Interventional Medicine2023，6，3： | 0 |
| 17 | Safety and activity of WX-0593(Iruplinalkib)in patients with ALK-or ROS1-rearranged advanced non-small cell lung cancer:a phase 1 dose-escalation and dose-expansion trial显示文摘WX-0593(Iruplinalkib)is a novel,highly selective oral ALK and ROS1 tyrosine kinase inhibitor(TKI).In this study,the safety,antitumor activity,and pharmacokinetics of WX-0593 were evaluated in advanced non-small cell lung cancer(NSCLC)patients with ALK or ROS1 rearrangement.In the dose-escalation phase and dose-expansion phase,patients were treated with WX-0593 until disease progression,unacceptable toxicity,or subject withdrawal.In the dose-escalation phase,the primary endpoints were maximum tolerated dose(MTD),dose-limiting toxicity(DLT),and safety assessed by investigators.In the dose-expansion phase,the primary endpoint was objective response rate(ORR)assessed by investigators.Between September 25,2017 and October 15,2018,a total of 153 patients received WX-0593 treatment.Two dose-limiting toxicities(DLTs)including one grade 3 QT interval prolonged and one grade 2 chronic heart failure were reported at the dose of 300 mg in one patient.MTD was not reached.Overall,140 of the 152(92%)patients experienced treatment-related adverse events(TRAEs)and 35 of the 152(23%)patients had TRAEs≥grade 3.The overall ORR was 59.3%(32 of 54)for the dose-escalation phase and 56.6%(56 of 99)for the dose-expansion phase.For patients who were ALK-rearranged and ALK TKI naive,the ORR were 81.0%(17 of 21)in the dose-escalation phase and 76.3%(29 of 38)in the dose-expansion phase,and for patients who previously received crizotinib as the only ALK TKI,the ORR were 38.1%(8 of 21)and 45.7%(21 of 46)for the two phases,respectively.For patients who were ROS1-rearranged,the ORR were 30.0%(3 of 10)in the dose-escalation phase and 44.4%(4 of 9)in the dose-expansion phase.WX-0593 showed favorable safety and promising antitumor activity in advanced NSCLC patients with ALK or ROS1 rearrangement. | Yuankai Shi Jian Fang Xuezhi Hao Shucai Zhang Yunpeng Liu Lin Wang Jianhua Chen Yi Hu Xiaosheng Hang Juan Li Chunling Liu Yiping Zhang Zhehai Wang Yanping Hu Kangsheng Gu Jian’an Huang Liangming Zhang Jinlu Shan Weiwei Ouyang Yanqiu Zhao Wu Zhuang Yan Yu Jun Zhao Helong Zhang Pei Lu Weidong Li Meimei Si Mingjing Ge Huaize Geng | 2022 | Signal Transduction and Targeted Therapy2022，7，2： | 0 |
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