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	题名	作者	年代	出处	被引量
1	Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma显示文摘AIM: To characterise expression of known E-cadherin repressors; Snail, Slug and Twist in the development of esophageal adenocarcinoma. METHODS: E-cadherin, Slug, Snail and Twist mRNA expression in Barrett's metaplasia and esophageal adenocarcinoma specimens was examined by real-time reverse transcription-polymerase chain reaction (RT-PCR). Semi-quantitative immunohistochemistry was used to examine cellular localisation and protein levels. The effect of Slug on epithelial mesenchymal transition (EMT) markers was examined by transfection of Slug into an adenocarcinoma line OE33.RESULTS: Cellular localisation of Slug in Barrett's metaplasia was largely cytoplasmic whilst in adenocarcinoma it was nuclear. Semi-quantitative analysis indicated that Slug was more abundant in adenocarcinoma compared to matched Barrett's metaplastic specimens. Snail and Twist were expressed in adenocarcinoma but were cytoplasmic in location and not induced compared to Barrett's mucosa. These observations were supported by mRNA studies where only Slug mRNA was shown to be over-expressed in adenocarcinoma and inversely correlated to E-cadherin expression. Overexpression of Slug in OE33 mediated E-cadherin repression and induced the mesenchymal markers vimentin and fibronectin.CONCLUSION: Progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing.	Paras Jethwa Mushal Naqvi Robert G Hardy Neil A Hotchin Sally Roberts Robert Spychal Chris Tselepis	2008	World Journal of Gastroenterology2008，14，7：	24
2	Effect of liquid properties on the performance of bubble column reactors with fine pore spargers 显示文摘	MOUZA A A DALAKOGLOU G K PARAS S V	2005	Chem Eng Sci2005，60，：	1
3	A reinvestigation of the structure of biruloquinone, a 9,10-phenanthrenequinone isola- ted from Mycosphaerella rubella 显示文摘	Armone A Nasini G de Para OV	1991	Phytochemistry1991，31，：	1
4	A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock 显示文摘	PRUNEDA-PAZ J L BRETON G PARA A	2009	Science2009，323，5920：	1
5	The inci-dence and risk factors of post-laparotomy adhesive sm all bowel obstruetion显示文摘	Barm paras G Branco BC Schn tiriger B	2010	J Gastrointest Surg2010，14，10：	1
6	Optimal design of a plate heat exchanger with undulated surface 显示文摘	KANARIS A G MOUZA A A PARAS S V	2009	International Journal of Thermal Sciences2009，48，：	1
7	Safety,pharmacokinetics, and antiviral activity of HGS004,anovel fully human IgG4 monoclonal antibody againstCCR5,in HIV-1-infected patients 显示文摘	Lalezari J Yadavalli G K Para M	2008	J Infect Dis2008，197，：	1
8	Albumin-furcella- ran complexes as cores for nanoencapsulation显示文摘	Jamr Z E Para G Jachimska B	2013	Colloids and Surfaces A: Physicochem and Eng Asp2013，441，：	1
9	Extension of nonoperative management of blunt pancreatic trauma to include grade Ⅲ injuries:a safety analysis显示文摘	Para G Casella C Di Betta E	2009	World J Surg2009，33，8：	1
10	Nontraumatic elevation of prostate specific antigen following cardiac surgery and extracorporeal cardiopulmonary bypass显示文摘	Hagood P G Para R O Rauscher J A	1994	J Urol1994，152，61：	1
11	Flow and heat transfer prediction in a corrugated plate heat exchanger using a CFD code显示文摘	KANARIS A G MOUZA A A PARAS S V	2006	Chemical Engineering and Technology2006，29，8：	1
12	A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock显示文摘	Pruneda-Paz J L Breton G Para A	2009	Science2009，323，：	1
13	Therapy with antipsychotic drugs as a risk factor for diabetes in schizophrenia: a case - control study 显示文摘	Rubio G Gomez - de - la - Camara A Ledesma F Buron JA Rodriguez- Morales A Martinez -Junquera G Grupo Espa? ol para el Estudio de la Diabetes en Pacientes Esquizofr6nicos	2006	Med Clin (Barc)2006，126，12：	1
14	Early outcome of corona- ry artery bypass grafting in patients with unstable angina 显示文摘	Paras I Bakhsh A Hussain G	2014	J Ayub Med Coll Abbottabad2014，26，3：	1
15	Myocophenolate mofetil prevents the progressive renal failure induced by 5/6 renal abalation in rats显示文摘	Romero F Radriguez IB Para G	1999	Kidney Int1999，55，3：	1
16	Therapywith antipsychotic drugs as a risk factor fordiabetes in schizophrenia:a case-control study 显示文摘	Rubio G Go mez-de-la-Ca mara A Ledesma F Buro n JA Rodri guez-Morales A Martl nez-Jun quera G Grupo Espa?ol para el Estudio de la Diabetes en Pacientes Esquizofre nicos	2006	Med Clin (Barc)2006，126，12：	1
17	The Hofmeister series effect in adsorption of cationic surfactants-theoretical description and experimental results显示文摘	G Para E Jarek P Warszynski	2006	Adv Coll Interface Sci2006，122，：	1
18	The emerging role of vitamin D binding protein in multiple sclerosis显示文摘	DISANTO G RAMAGOPALAN SV PARA AE		0，，03：	1
19	Interactions of aqueous drops with electrodes in dielectric liquids显示文摘	ADAMCZYK Z PARA G PIASECKI W	2003	Bulletin of the Polish Academy of Science Chemistry2003，51，34：	1
20	Antioxidant activity of Cissampelos pareira on benzo(a)pyrene-induced mucosal injury in mice显示文摘	G Amresh Chandana Venkateswara Rao Paras Nath Singh	2007	Nutrition Research2007，，10：	1

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