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20篇 您的检索式:作者名="PAVEL P M"
    题名 作者 年代 出处 被引量
1Treatment of acute agitation in psychotic disorders显示文摘PAVEL M JAN P JAROMIR S 2005Neuroendocrinol Lett2005,26,4:1
2Beam quality factor of higher order modes in a step-index fiber显示文摘HIDEHIKO Y PAVEL P MASUD M 2006IEEE J Lightwave Technology2006,24,3:1
3Distributed multi-agent architecture for automation systms显示文摘Francisco P M Pavel Tichy Petr Slechta 2004Expert System with Applications2004,26,:1
4Mariella Constantinescu, Study of one dimensional solidification with free convection in an infinite plate geometry显示文摘Stefania Zuca Pavel P M 1999Energy Conversion & Management1999,40,:1
5Lanreotide in metastatic enteropancreatic neuroendocrine tumors显示文摘CAPLIN M E PAVEL M RUSZNIEWSKI P 2014N Engl J Med2014,371,16:1
6Characterization of cells obtained by mechanical and enzymatic means from human melanoma, sarcoma, and lung tumors显示文摘SLOCUM K H PAVELIC P Z RUSTUM M Y 1981Cancer Research1981,41,:1
7Study of one dimensional solidification with free convection in an infinite plate geometry显示文摘Stefania Z Pavel P M Mariella C 1999Energy Conversion & Management1999,,40:1
8Aberrant lipid organization in stratum corneum of patients with atopic dermatitis and lamellar ichthyosis显示文摘Pilgram G S K Vissers D C J van der Meulen H Pavel S Lavrijsen S P M Bownstra J A Koerten H K 2001J Invest Dermatol2001,117,3:1
9Diet Shifts Towards Meat and the Effects on Cereal Use:Can We Feed the Animals in 2030显示文摘KEYZER M A MERBIS M D PAVEL I F P W 0,,2:1
10Single Core Fully Integrated CMOS Micro-fluxgate Magnetometer 显示文摘P M Drljaca Pavel Kejik Franck Vincent 2004Sensors and Actuators A2004,110,13:1
11Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates显示文摘BACKGROUND The development of regenerative therapy for human spinal cord injury(SCI)is dramatically restricted by two main challenges:the need for a safe source of functionally active and reproducible neural stem cells and the need of adequate animal models for preclinical testing.Direct reprogramming of somatic cells into neuronal and glial precursors might be a promising solution to the first challenge.The use of non-human primates for preclinical studies exploring new treatment paradigms in SCI results in data with more translational relevance to human SCI.AIM To investigate the safety and efficacy of intraspinal transplantation of directly reprogrammed neural precursor cells(drNPCs).METHODS Seven non-human primates with verified complete thoracic SCI were divided into two groups:drNPC group(n=4)was subjected to intraspinal transplantation of 5 million drNPCs rostral and caudal to the lesion site 2 wk post injury,and lesion control(n=3)was injected identically with the equivalent volume of vehicle.RESULTS Follow-up for 12 wk revealed that animals in the drNPC group demonstrated a significant recovery of the paralyzed hindlimb as well as recovery of somatosensory evoked potential and motor evoked potential of injured pathways.Magnetic resonance diffusion tensor imaging data confirmed the intraspinal transplantation of drNPCs did not adversely affect the morphology of the central nervous system or cerebrospinal fluid circulation.Subsequent immunohistochemical analysis showed that drNPCs maintained SOX2 expression characteristic of multipotency in the transplanted spinal cord for at least 12 wk,migrating to areas of axon growth cones.CONCLUSION Our data demonstrated that drNPC transplantation was safe and contributed to improvement of spinal cord function after acute SCI,based on neurological status assessment and neurophysiological recovery within 12 wk after transplantation.The functional improvement described was not associated with neuronal differentiation of the allogeneic drNPCs.Instead,directed drNPCs migration to the areas of active growth cone formation may provide exosome and paracrine trophic support,thereby further supporting the regeneration processes.Vladimir P Baklaushev Oleg V Durov Vladimir A Kalsin Eugene V Gulaev Sergey V Kim Ilya L Gubskiy Veronika A Revkova Ekaterina M Samoilova Pavel A Melnikov Dzhina D Karal-Ogly Sergey V Orlov Alexander V Troitskiy Vladimir P Chekhonin Alexander V Averyanov Jan-Eric Ahlfors 2021World Journal of Stem Cells2021,13,5:1
12HPLC quantification of seven quaternary benzo phenanthridine alkaloids in six species of the family Papaveraceae显示文摘JANA S HANA B HANA P PAVEL M EVA T 2007Journal of Pharmaceutical and Biomedical Analysis2007,44,1:1
13Lanreotide in metastatic enteropancreatic neuroendocrine tumors 显示文摘Caplin ME Pavel M Ruszniewski P 2014N Engl J Med2014,371,16:1
14An acceleration measurements-based approach for helicopter nonlinear flight control using incremental nonlinear dynamic inversion显示文摘Simplício P Pavel M D Van Kampen E 2013Control Engineering Practice2013,21,8:1
15Quenching of spontaneous emission via quantum interference显示文摘 PAVEL P SCULLY M O 1997Phys Rev A1997,55,:1
16Naked TSH receptor DNA vaccination: a Thl T cell response in which interferon-γ production, rather than antibody, dominates the immune response in mice 显示文摘Pavel P Xin M Y Loredana F 2001Endocrinology2001,142,8:1
17Distributed multi-agent architecture for automation systms显示文摘Francisco P M Pavel Tichy Petr Slechta 2004Expert System with Applications2004,26,:1
18Laboratory assessment of factors affecting soil clogging of soil aquifer treatment systems显示文摘Pavelic P Dillon P J Mucha M 2011Water Research2011,45,10:1
19Study of one dimensional solidification with free convection in an infinite plate geometry显示文摘Zuca S Pavel P M Mariella Constantinescu 1999Energy Conversion & Management1999,,40:1
20Studyof one dimensional solidification with free convectionin an infinite plate geometry显示文摘ZUCA S PAVEL P M CONSTANTINESCU M 1999Energy Conversionand Management1999,40,3:1
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