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| 1 | Cigarette smoking, dietary habits and genetic polymorphisms in GSTT1, GSTM1 and CYP1A1 metabolic genes: A case-control study in oncohematological diseases显示文摘AIM To analyze the association between oncohematological diseases and GSTT1 /GSTM1 /CYP1A1 polymorphisms, dietary habits and smoking, in an argentine hospitalbased case-control study.METHODS This hospital-based case-control study involved 125 patients with oncohematological diseases and 310 control subjects. A questionnaire was used to obtain sociodemographic data and information about habits. Blood samples were collected, and DNA was extracted using salting out methods. Deletions in GSTT1 and GSTM1 (null genotypes) were addressed by PCR. CYP1A1 MspI polymorphism was detected by PCR-RFLP. Odds ratio(OR) and 95%CI were calculated to estimate the association between each variable studied and oncohematological disease.RESULTS Women showed lower risk of disease compared to men(OR 0.52, 95%CI: 0.34-0.82, P = 0.003). Higher levels of education(> 12 years) were significantly associated with an increased risk, compared to complete primary school or less(OR 3.68, 95%CI: 1.82-7.40, P < 0.001 adjusted for age and sex). With respect to tobacco, none of the smoking categories showed association with oncohematological diseases. Regarding dietary habits, consumption of grilled/barbecued meat 3 or more times per month showed significant association with an increased risk of disease(OR 1.72, 95%CI: 1.08-2.75, P = 0.02). Daily consumption of coffee also was associated with an increased risk(OR 1.77, 95%CI: 1.03-3.03, P = 0.03). Results for GSTT1, GSTM1 and CYP1A1 polymorphisms showed no significant association with oncohematological diseases. When analyzing the interaction between polymorphisms and tobacco smoking or dietary habits, no statistically significant associations that modify disease risk were found. CONCLUSION We reported an increased risk of oncohematological diseases associated with meat and coffee intake. We did not find significant associations between genetic polymorphisms and blood cancer. | María Belén Cerliani Walter Pavicic Juan Antonio Gili Graciela Klein Silvia Saba Silvina Richard | 2016 | World Journal of Clinical Oncology2016,7,5: | 1 |
| 2 | Vibration serviceability of footbridges under human-induced excitation:a literature review显示文摘 | Zivanovic S Pavic A Reynolds P | 2005 | Journal of Sound and Vibration2005,279,12: | 1 |
| 3 | Subacute meningoradiculomye loencephalitis due to cryptococcosis infection显示文摘 | Drouet A Amah Y Pavic M | 2005 | Rev Med Interne2005,26,5: | 1 |
| 4 | Mathematical model to generate asymmetric pulses due to human jumping显示文摘 | Racic V Pavic A | 2009 | ASCE Journal of Engineering Mechanics2009,135,10: | 1 |
| 5 | Vibration serviceability of footbridge under human-induced excitation: a literature review 显示文摘 | Zivanovic S Pavic A Reynolds P | 2005 | Journal of Sound and Vibration2005,279,1: | 1 |
| 6 | Reproduction and application of human bouncing and jumping forces from visual Marker data显示文摘 | Racic V Brewnjohn J M W Pavic A | 2010 | Journal of Sound and Vibration2010,329,16: | 1 |
| 7 | Experimental assessment of vi- bration serviceability of existing office floors under hu- man-induced excitation显示文摘 | Pavic A Reynolds P | 1999 | Experimental Techniques1999,23,5: | 1 |
| 8 | Vibration serviceability of footbridges under human-induced excitation: a literature review 显示文摘 | Zivanovic S Pavic A Reynolds P | 2005 | Journal of Sound and Vibration2005,279,: | 1 |
| 9 | Critical review of guidelines for checking vibration serviceability of post-tensioned concrete floors 显示文摘 | Pavic A Reynolds P Waldron P | 2001 | Cement and Concrete Composites2001,23,1: | 1 |
| 10 | A spectral density approach for modeling continuous vertical forces on pedestrian structures due to walking显示文摘 | Brownjohn J M W Pavic A Omenzetter P | 2004 | Canadian Journal of Civil Engineering2004,31,1: | 1 |
| 11 | Quantification of dynamic excitation potential of pedestrian population crossing footbridges 显示文摘 | Ž ivanović S Pavic A | 2011 | Shock and Vibration2011,18,4: | 1 |
| 12 | Vibration Serviceability of Footbridges Under Human induced Excitation:A Literature Review显示文摘 | ZIVANOVIC S PAVIC A REYNOLDS P | 2005 | Journal of Sound and Vibration2005,279,12: | 1 |
| 13 | Vibration service- ability of footbridges under human-induced excitation:a literature review显示文摘 | Zivanovic S Pavic A Reynolds P | 2005 | Journal of Sound and Vibra- tion2005,279,12: | 1 |
| 14 | Probability-based prediction of multi-mode vibration response to walking excitation 显示文摘 | Zivanovic S Pavic A Reynolds P | 2007 | Engineering Structures2007,29,6: | 1 |
| 15 | Experimental identification and analytical modeling of human walking forces:Literature review 显示文摘 | Racic V Pavic A Brownjohn J M W | 2009 | Journal of Sound and Vibration2009,326,12: | 1 |
| 16 | Human-structure dynamic interaction in civil engineering dynamics: A literature review 显示文摘 | Sachse R Pavic A Reynolds P | 2003 | The Shock and Vibration Digest2003,35,1: | 1 |
| 17 | Use of bo- vine primary mammary epithelial cell for the compari- son of adherence and invasion ability of Staphylococ- cusaureus stains显示文摘 | Hensen S M Pavicic M P Lohuis J A | | 0,,03: | 1 |
| 18 | Parametric study of modal properties of damped two-degree-of-freedom crowd-structure dynamic systems显示文摘 | Sacbse R Pavic A Reynolds P | 2004 | Journal of Sound and Vibration2004,274,325: | 1 |
| 19 | Modal testing and finite-element model updating of a lively open-plan composite building floor 显示文摘 | Pavic A Miskovic Z Reynolds P | 2007 | Journal of Structural Engineering2007,133,4: | 1 |
| 20 | Use of bovine prima- ry mammary epithelial cells for the comparison of adherence and invasion ability of staphylococcus aureus strains显示文摘 | Hensen S M Pavicic M J Lohuis J A | 2000 | Journal of Dairy Science2000,83,41: | 1 |