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| 1 | Chinese herbal medicine for subacute thyroiditis:a systematic review of randomized controlled trials显示文摘OBJECTIVE:To evaluate the effectiveness and safety of Chinese herbal medicine(CHM) in the treatmentofsubacutethyroiditis.METHODS: Randomized controlled trials found in PubMed, Cochrane Library, and three Chinese databases were selected. RevMan 5.2 software was used to analyze the data with relative risk or mean difference, expressed with 95% of confidence interval. The quality of trials was assessed and gradedthe quality of evidence with GRADE profiler software.RESULTS: Twenty one studies were included. CHM was superior to Western Medicine(include prednisone and NSAIDs) in abating fever, relieving thyroid pain, recovering blood sedimentation, improving thyroid function, and preventing hypothyroidism(P<0.05), while no statistical differences were found in eliminating goiter and reducing relapse rate.CHM plusWestern Medicine were superior toWestern Medicine in abating fever, relieving thyroid pain, eliminating goiter, and reducing relapse rate,while no statistical differences(P>0.05) were found in recovering blood sedimentation and improving thyroid function. The incidence of adverse reactions in treatment group was lower than that in control group(relative risk was 0.12 and 95% confidence interval was 0.03-0.51). The methodological quality of trials is generally poor with a high risk of bias.CONCLUSION: CHM(particularly CHM combined withWestern Medicine) used to treat subacute thyroiditis may improve clinical symptoms and signs,reduce relapse rate, and alleviate the side effects of hormones. Due to poor methodological quality of included trials, further more high-quality studies are warranted to confirm the effectiveness and safety of CHM. | Hui Luo Meng Lü Xiaohua Pei Zhongyuan Xia | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 16 |
| 2 | Design of 16S rRNA gene primers for 454 pyrosequencing of the human foregut microbiome显示文摘AIM:To design and validate broad-range 16S rRNA primers for use in high throughput sequencing to classify bacteria isolated from the human foregut microbiome.METHODS:A foregut microbiome dataset was constructed using 16S rRNA gene sequences obtained from oral,esophageal,and gastric microbiomes produced by Sanger sequencing in previous studies represented by 219 bacterial species.Candidate primers evaluated were from the European rRNA database.To assess the effect of sequence length on accuracy of classification,16S rRNA genes of various lengths were created by trimming the full length sequences.Sequences spanning various hypervariable regions were selected to simulate the amplicons that would be obtained using possible primer pairs.The sequences were compared with full length 16S rRNA genes for accuracy in taxonomic classification using online software at the Ribosomal Database Project (RDP).The universality of the primer set was evaluated using the RDP 16S rRNA database which is comprised of 433 306 16S rRNA genes,represented by 36 phyla.RESULTS:Truncation to 100 nucleotides(nt)downstream from the position corresponding to base 28 in the Escherichia coli 16S rRNA gene caused misclassification of 87(39.7%)of the 219 sequences,compared with misclassification of only 29(13.2%)sequences with truncation to 350 nt.Among 350-nt sequence reads within various regions of the 16S rRNA gene,the reverse read of an amplicon generated using the 343F/798R primers had the least(8.2%)effect on classification.In comparison,truncation to 900 nt mimicking single pass Sanger reads misclassified 5.0%of the 219 sequences.The 343F/798R amplicon accurately assigned 91.8%of the 219 sequences at the species level.Weighted by abundance of the species in the esophageal dataset,the 343F/798R amplicon yielded similar classification accuracy without a significant loss in species coverage(92%).Modification of the 343F/798R primers to 347F/803R increased their universality among foregut species.Assuming that a typicalpolymerase chain reaction can tolerate 2 mismatches between a primer and a template,the modified 347F and 803R primers should be able to anneal 98%and 99.6%of all 16S rRNA genes in the RDP database.CONCLUSION:347F/803R is the most suitable pair of primers for classification of foregut 16S rRNA genes but also possess universality suitable for analyses of other complex microbiomes. | Carlos W Nossa William E Oberdorf Jφrn A Aas Bruce J Paster Todd Z DeSantis Eoin L Brodie Daniel Malamud Michael A Poles Zhiheng Pei | 2010 | World Journal of Gastroenterology2010，16，33： | 16 |
| 3 | Relationship between Geological Structures and Hydrocarbon Enrichment of Different Depressions in the Bohai Bay Basin显示文摘The Bohai Bay Basin contains many depressions with varying degrees of hydrocarbon enrichment associated with the geological structures of different depressions. This study discussed the relationship between the geological structures and hydrocarbon enrichment of the depressions in the Bohai Bay Basin. Based on the Paleogene strata distribution and the length to width ratio of different depressions, their geological structures are divided into three types in plan-view: open(length/width < 2), narrow(length/width > 4) and transitional types(length/width 2–4). In cross section, the geological structures can be divided into dustpan I, dustpan II and double-faulted types. Based on tectonic evolution and sedimentary characteristics, the depressions are classified into early-formed, inherited and late-formed categories. Generally, narrow depressions are mainly located in the northeast and southwest of the Bohai Bay Basin, while open depressions are dominantly distributed in the central area of the basin; late-formed depressions are mainly around the Bohai sea area, and early-formed depressions are mostly located in the periphery of the basin. Geological structures of the depressions control the formation of the source, reservoir and cap rocks as well as hydrocarbon accumulation setting, and further influence the pay zones and oil-bearing sequence. In detail, dustpan II and doublefaulted depressions mainly have A-type sags, which often possess better hydrocarbon generation conditions than dustpan I ones; hydrocarbons in open dustpan II depressions tend to accumulate in the central uplift areas or buried hill, while those in narrow dustpan I depressions always accumulate in gentle slope belts. The oil-bearing sequence for different evolutional depressions corresponds well with the sedimentary strata of the main development stages of depressions. In early-formed depressions, hydrocarbons are mainly enriched in deeply buried reservoirs, while in late-formed depressions hydrocarbons are abundant in the relatively shallow traps. In summary, most inherited and late-formed dustpan II depressions are enriched in hydrocarbons due to their extensive source rocks and good source–reservoir–seal assemblages, whereas dustpan I and early-formed depressions are relatively poor in hydrocarbons. | JIANG Youlu LIU Hua SONG Guoqi WANG Yongshi LIU Pei Lü Xueying | 2015 | Acta Geologica Sinica(English Edition)2015，89，6： | 13 |
| 4 | Opposite effects of nitrogen fertilization and plastic film mulching on crop N and P stoichiometry in a temperate agroecosystem显示文摘Aims Crop nitrogen(N)and phosphorus(P)stoichiometry can influence food nutritive quality and many ecosystem processes.However,how and why N and P stoichiometry respond to long-term agricul-tural management practices(e.g.N fertilization and film mulching)are not clearly understood.Methods We collected maize tissues(leaf,stem,root and seed)and soil sam-ples from a temperate cropland under 30-year continuous N fer-tilization and plastic film mulching treatments,measured their C,N and P concentrations(the proportion(%)relative to the sample mass),and used structural equation models to uncover the re-sponding mechanisms for crop N and P contents(the total amount(g/m2)in crop biomass).Important Findings Long-term N fertilization increased N concentrations in all crop tissues but sharply decreased P concentrations in vegetative tis-sues(leaf,stem and root),thereby reducing their C/N ratio and increasing C/P and N/P ratios.The drop in P concentration in vegetative tissues was due to the dilution effect by biomass in-crement and the priority of P supply for seed production.In con-trast,film mulching decreased N concentration but increased P concentrations in most crop tissues,thereby increasing C/N ratio and reducing C/P and N/P ratios.Film mulching increased crop P content by increasing soil temperature and moisture;whereas,mulching showed little effect on crop N content,because a posi-tive effects of soil temperature may have canceled out a negative effect by soil moisture.This indicated a decoupling of P and N uptake by crops under film mulching.In conclusion,N fertiliza-tion and plastic film mulching showed opposite effects of on crop N and P stoichiometry. | Fan Ding Shuangyi Li Xiao-Tao Lü Feike A.Dijkstra Sean Schaeffer Tingting An Jiubo Pei Liangjie Sun Jingkuan Wang | 2019 | Journal of Plant Ecology2019，12，4： | 8 |
| 5 | Mitigation of greenhouse gases released from mining activities:A review显示文摘Climate changes that occur as a result of global warming caused by increasing amounts of greenhouse gases(GHGs)released into the atmosphere are an alarming issue.Controlling greenhouse gas emissions is critically important for the current and future status of mining activities.The mining industry is one of the significant contributors of greenhouse gases.In essence,anthropogenic greenhouse gases are emitted directly during the actual mining and indirectly released by the energy-intensive activities associated with mining equipment,ore transport,and the processing industry.Therefore,we reviewed both direct and indirect GHG emissions to analyze how mining contributes to climate change.In addition,we showed how climate change impacts mineral production.This assessment was performed using a GHG inventory model for the gases released from mines undergoing different product life cycles.We also elucidate the key issues and various research outcomes to demonstrate how the mining industry and policymakers can mitigate GHG emission from the mining sector.The review concludes with an overview of GHG release reduction and mitigation strategies. | Li-yuan Liu Hong-guang Ji Xiang-feng Lü Tao Wang Sheng Zhi Feng Pei Dao-lu Quan | 2021 | International Journal of Minerals,Metallurgy and Materials2021，28，4： | 4 |
| 6 | Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis显示文摘AIM To investigate the effects of orally gavaged aqueous rhubarb extract(RE) on 5-fluorouracil(5-FU)-induced intestinal mucositis in rats. METHODS Female Dark Agouti rats(n = 8/group) were gavaged daily(1 mL) with water, high-dose RE(HDR; 200 mg/kg) or low-dose RE(LDR; 20mg/kg) for eight days. Intestinal mucositis was induced(day 5) with 5-FU(150 mg/kg) via intraperitoneal injection. Intestinal tissue samples were collected for myeloperoxidase(MPO) activity and histological examination. Xenopus oocytes expressing aquaporin 4 water channels were prepared to examine the effect of aqueous RE on cell volume, indicating a potential mechanism responsible for modulating net fluid absorption and secretion in the gastrointestinal tract. Statistical significance was assumed at P < 0.05 by one-way ANOVA. RESULTS B o d y w e i g h t w a s s i g n i f i c a n t l y r e d u c e d i n r a t s administered 5-FU compared to healthy controls(P < 0.01). Rats administered 5-FU significantly increased intestinal MPO levels(≥ 307%; P < 0.001), compared to healthy controls. However, LDR attenuated this effect in 5-FU treated rats, significantly decreasing ileal MPO activity(by 45%; P < 0.05), as compared to 5-FU controls. 5-FU significantly reduced intestinal mucosal thickness(by ≥ 29% P < 0.001) as compared to healthy controls. LDR significantly increased ileal mucosal thickness in 5-FU treated rats(19%; P < 0.05) relative to 5-FU controls. In xenopus oocytes expressing AQP4 water channels, RE selectively blocked water influx into the cell, induced by a decrease in external osmotic pressure. As water efflux was unaltered by the presence of extracellular RE, the directional flow of water across the epithelial barrier, in the presence of extracellular RE, indicated that RE may alleviate water loss across the epithelial barrier and promote intestinal health in chemotherapy-induced intestinal mucositis.CONCLUSION In summary, low dose RE improves selected parameters of mucosal integrity and reduces ileal inflammation, manifesting from 5-FU-induced intestinal mucositis. | Juliana E Bajic Georgina L Eden Lorrinne S Lampton Ker Y Cheah Kerry A Lymn Jinxin V Pei Andrea J Yool Gordon S Howarth | 2016 | World Journal of Gastroenterology2016，22，37： | 3 |
| 7 | Perennial aneuploidy as a potential material for gene introgression between maize and Zea perennis显示文摘Hybridization,which allows for gene flow between crops,is difficult between maize and Zea perennis.In this study,we aim to initiate and study gene flow between maize and Z.perennis via a special aneuploid plant(MDT) derived from an interspecific hybrid of the two species.The chromosome constitution and morphological characters of MDT as well as certain backcross progenies were examined.Results from genomic in situ hybridization(GISH) indicate that aneuploid MDT consisted of nine maize chromosomes and 30 Z.perennis chromosomes.The backcross progenies of MDTxmaize displayed significant diversity of vegetative and ear morphology;several unusual plants with specific chromosome constitution were founded in its progenies.Some special perennial progeny with several maize chromosomes were obtained by backcrossing MDT with Z.perennis,and the first whole chromosome introgression from maize to Z.perennis was detected in this study.With this novel material and method,a number of maize-tetraploid teosinte addition or substitution lines can be generated for further study,which has great significance to maize and Z.perennis genetic research,especially for promoting introgression and transferring desirable traits. | FU Jie YANG Xiu-yan CHENG Ming-jun L Gui-hua WANG Pei WU Yuan-qi ZHENG Ming-min ZHOU Shu-feng RONG Ting-zhao TANG Qi-lin | 2015 | Journal of Integrative Agriculture2015，14，5： | 2 |
| 8 | Polymer-enhance diffraction in an azo-dye-doped li-quid crystal显示文摘 | Pei M L Wang Y J Carlisle O O | 2001 | Society of Photo-Optical Instrumentation Engineers2001，40，8： | 1 |
| 9 | Haploinsufficiency of p18INK4c sensitizes mice to carcinogen-induced tumorigenesis显示文摘 | BAI F PEI X H VIRGINIA L G | 2003 | Molecular and Cellular2003，23，4： | 1 |
| 10 | Triassic volcanism in eastern Heilongjiang and Jilin provinces, NE China: chronology, geochemistry, and tectonic implications显示文摘 | Xu W L Ji w Q Pei F P | 2009 | Journal of Asian Earth Sciences2009，34，： | 1 |
| 11 | Identification of c-myc as a down-stream target for pituitary tumor-transforming gene显示文摘 | Pei L | 2001 | J Biol Chem2001，276，11： | 1 |
| 12 | Conjugate heat and mass transfer in membrane-formed channels in all entry regions显示文摘 | Zhang L Z Liang C H Pei L X | 2010 | International Journal of Heat and Mass Transfer2010，53，56： | 1 |
| 13 | Effects of density on variation in individual growth and differentiation in endo- crine response of Japanese sea cucumber (Apostichopus ja- ponicus Selenka)显示文摘 | Pei S R Dong S L Wang F | 2012 | Aquaculture2012，，： | 1 |
| 14 | Preparation of silicon carbide nanotubes by hydrothermal method显示文摘 | Pei L Z Tang Y H Chen Y W | 2006 | J Appl Phys2006，99，11： | 1 |
| 15 | 显示文摘 | Chuu D S Won W L Pei J H | 1994 | Phys Rev B1994，49，14： | 1 |
| 16 | Investigation on the electrical properties and inhomogeneous distribution of ZnO: Al thin films prepared by dc magnetron sputtering at low deposition temperature显示文摘 | Zhang X B Pei Z L Gong J | 2007 | Journal of Applied Physics2007，101，01： | 1 |
| 17 | Low Temperature Growth and Characterizations of Single Crystalline CuGeO3 Nanowires 显示文摘 | Pei L Z Zhao H S Tan W | 2009 | Cost Eng Comm2009，11，7： | 1 |
| 18 | Treatment of landfill leachate wastewater by nanofihration membrane 显示文摘 | MOHAMMAD A W HILAL N PEI L Y | 2004 | Interna- tional Journal of Green Energy2004，1，2： | 1 |
| 19 | Preparation of copper germanate nanowires with good electrochemical sensing proper ties显示文摘 | PEI L Z WANG J F YANG L J etal | 2011 | Crystal Research and Technology2011，46，1： | 1 |
| 20 | Pcroxisome proliferator-activatcd receptor gamma promotes neuroprotection by modulating cyclin D1 expression after focal cerebral ischemia 显示文摘 | Pei L Zhang Y Zhang Y | 2010 | Can J Physiol Phannacol2010，88，7： | 1 |
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