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| 1 | Glu-1和Glu-3等位变异对小麦加工品质的影响显示文摘Glu 1位点等位基因编码的高分子量麦谷蛋白亚基 (HMW GS)和Glu 3位点等位基因编码的低分子量麦谷蛋白亚基 (LMW GS)是决定小麦加工品质的重要因素。用优质面包小麦中优 95 0 7的两个杂交组合 ,即中优 95 0 7/鲁麦 5号和中优 95 0 7/晋麦 4 5F5代 ,澳大利亚优质面包小麦Sunstate的两个杂交组合 ,即Sunstate/济南 16和Sunstate/鲁麦 2 1F2 代 ,研究了Glu 1和Glu 3位点等位变异对小麦加工品质的影响。结果表明 ,当材料为非 1BL/1RS易位系时 ,位点对小麦加工品质的贡献大小为Glu D1>Glu A3≥Glu B1;当材料为 1BL/1RS易位系时 ,位点对小麦加工品质的贡献大小为Glu B3>Glu D1>Glu A1。 1BL/1RS易位对SDS沉降值、和面时间和耐揉性均有显著负面影响。就单个亚基而言 ,Glu A1位点 1>N ,Glu B1位点 17+18>7+8>7+9,Glu D1位点 5 +10 >2 +12、3+12和 4 +12 ,Glu A3位点GluA3d和GluA3b >Glu A3a ,Glu B3位点GluB3d >GluB3b和GluB3h >GluB3j。亚基组合为 1、7+9、5 +10、GluA3d、GluB3b和 1、7+8、5 +10、Glu A3d、GluB3d的材料 ,加工品质优良 ,亚基组合为 1、7+8、2 +12、GluA3a、GluB3d和N、7+9、3+12、GluA3d、GluB3j的材料加工品质较差。 | 刘丽 周阳 何中虎 阎俊 张艳 Pea R J | 2004 | 作物学报2004，30，10： | 54 |
| 2 | 软质小麦品质性状与酥性饼干品质参数的关系研究显示文摘选用我国17份软质小麦品种(系)在3点种植2年,研究软质小麦品质性状与酥性饼干品质的关系,探讨优质饼干品种的筛选指标。结果表明,粉质仪和拉伸仪参数与饼干品质的相关系数较小;吹泡仪弹性、吹泡仪弹性,延伸性、碱水保持力(AWRC)、碳酸钠溶剂保持力(SRC)和蔗糖SRC与饼干直径关系密切,相关系数分别为-0.79、-0.75、-0.78、-0.79和-0.80,可作为饼干品质的筛选指标。筛选出建麦1号、皖麦19和皖麦48三个饼干品质优良的品种,提出了优质饼干小麦品种的具体品质指标,即籽粒硬度(SKCS)1~40,籽粒蛋白质含量9.0%~11.5%,面粉蛋白质含量8.0%~10.0%,吹泡仪弹性≤40mm,弹性,延伸性≤0.50,吹泡仪能量≤75×10^-4J,碱水保持力≤59%,水SRC≤53%,碳酸钠SRC≤66%,乳酸SRC≤83%,蔗糖SRC≤87%,饼干直径≥480mm。 | 张岐军 张艳 何中虎 R J Pea | 2005 | 作物学报2005，31，9： | 58 |
| 3 | 不同加水量对北方馒头加工品质影响的研究显示文摘加水量是影响馒头加工品质的重要因素。用3种不同筋力的6个小麦面粉和5个水平加水量研究了加水量与北方馒头品质的关系。结果表明,在粉质仪测定的吸水率范围内,加水量显著影响馒头重量、体积、宽度、高度、比容及延展率。不同筋力面粉的馒头品质对加水量变化的敏感性不同。加水量与弱筋馒头表面亮度、色泽、光滑度、结构、压缩张弛性及总评分呈显著或极显著负相关(r=-0.663~-0.962),但在一定范围内,加水量增加能显著改善强筋馒头表面光滑度和内部结构(r=0.877,0.768)。强、中、弱筋面粉制作北方馒头的最适加水量分别为粉质仪吸水率(FWA)的85%、80%和70%~75%。压缩张弛性(SR)与强、中、弱筋馒头总评分呈极显著正相关,决定系数分别为0.94、0.88和0.72,可作为馒头品质评价的有效指标。 | 陈东升 张艳 何中虎 王德森 Pea R J | 2005 | 作物学报2005，31，6： | 28 |
| 4 | 肥胖患者的冠状动脉微血管功能障碍和心血管病风险显示文摘全世界有〉5亿的肥胖人群,其心血管病风险增加的病理生理机制是复杂的,并且可能涉及脂肪细胞相关因子的过量分泌,导致血管氧化应激增加,神经激素活性上调,以及低度全身炎症,可能导致交感神经系统激活增加,血管张力改变,冠状动脉微血管功能障碍(coronary microvascular dysfunction, CMD) 。 | Bajaj NS Osborne MT Gupta A Tavakkoli A Bravo PE Vita T Bibbo CF Hainer J Dorbala S Blankstein R Bhatt DL Di Carli MF Taqueti VR 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，9： | 11 |
| 5 | 骨折相关性感染定义的共识显示文摘骨折相关性感染(fracture related infection,FRI)是创伤骨科一种常见的严重并发症.迄今为止,尚无明确定义,因此很难对该并发症带来的影响进行准确评估和对现有的研究展开比较.为解决这一难题,在AO基金会的支持下,我们成立了一个由科学家和医学专家组成的专家组,旨在对FRI定义达成的共识. | Metsemakers WJ Morgenstern M McNally MA Moriarty TF McFadyen I Scarborough M Athanasou NA Ochsner PE Kuehl R Raschke M Borens O 谢肇 Velkes S Hungerer S Kates SL Zalavras C Giannoudis PV Richard RG Verhofstad MH 喻胜鹏 孙东 汪小华 | 2018 | 中华骨科杂志2018，38，9： | 8 |
| 6 | Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis显示文摘AIM: To investigate the single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition and the susceptibility to pouchitis or pouchitis severity.METHODS: Analyses of CD14 -260C>T, CARD15/NOD2 3020insC, Toll-like receptor (TLR)4 +896A>G,TLR9 -1237T>C, TLR9+ 2848G>A, and IRAKM +22148G>A SNPs were performed in 157 ileal-pouch anal anastomosis (IPAA) patients (79 patients who did not develop pouchitis, 43 infrequent pouchitis patients,35 chronic relapsing pouchitis patients) and 224 Italian Caucasian healthy controls.RESULTS: No significant differences were found in SNP frequencies between controls and IPAA patients.However, a significant difference in carriership frequency of the TLR9-1237C allele was found between the infrequent pouchitis and chronic relapsing pouchitis groups [P = 0.028, odd's ratio (OR) = 3.2, 95%CI = 1.2-8.6].This allele uniquely represented a 4-locus TLR9 haplotype comprising both studied TLR9 SNPs in Caucasians.Carrier trait analysis revealed an enhanced combined carriership of the alleles TLR9 -1237C and CD14 -260T in the chronic relapsing pouchitis and infrequent pouchitis group (P = 0.018, OR = 4.1, 95%CI = 1.4 -12.3).CONCLUSION: There is no evidence that the SNPs predispose to the need for IPAA surgery. The significant increase of the combined carriership of the CD14 -260T and TLR9 -1237C alleles in the chronic relapsing pouchitis group suggests that these markers identify a subgroup of IPAA patients with a risk of developing chronic or refractory pouchitis. | KM Lammers S Ouburg SA Morré JBA Crusius P Gionchetti F Rizzello C Morselli E Caramelli R Conte G Poggioli M Campieri AS Pea | 2005 | World Journal of Gastroenterology2005，11，46： | 7 |
| 7 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 8 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 9 | The essential nature of the ubiquitous 26-kilobase circular replicon of Borreliaburgdorferi显示文摘 | Byram R Stewart PE Rosa P | 2004 | J Bacteriol2004，186，： | 1 |
| 10 | Valsartan reduces the incidence of artrial fibrillation in patients with heart failure:results from the Valsartan Heart Failure Trail(Val -HeFT)显示文摘 | Latini R Carson PE | 2005 | Am Heart J2005，149，3： | 1 |
| 11 | Near fatal posterior reversible encephalopathy syndrome complicating chronic liver failure and treated by induced hypothermia and dialysis:a case report显示文摘 | Chawla R Smith D Marik PE | 2009 | J Med Case Rep2009，3，： | 1 |
| 12 | Intravitreal triamcinolone and elevated intraocular pressure显示文摘 | Wingate R J Beaumont PE | 1999 | Aust N Z J Ophthalmol1999，27，： | 1 |
| 13 | Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine显示文摘 | Wang R Doolan D L Pe T P | 1998 | Science1998，282，： | 1 |
| 14 | Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: results from the Valsartan Heart Failure Trial (Val-HeFT) 显示文摘 | Maggloni AP Latini R Carson PE | 2005 | Am Heart J2005，149，3： | 1 |
| 15 | A prospective study of age trends in cervical human papillomavirus acquisition and persistence in Guanacaste,Costa Rica显示文摘 | Castle PE Schiffman M Herrero R | 2005 | J Infect Dis2005，191，11： | 1 |
| 16 | Nicotinic Acid Limitation Regulates Silencing of Candida Adhesins during UTI显示文摘 | Domergue R Casta(n)o I de Las Pe(n)as A | | 0，，5723： | 1 |
| 17 | Surgery for recurrent goi- tre: its complications and their risk factors 显示文摘 | Muller PE Jakoby R Heinert G | 2001 | Eur J Surg2001，167，11： | 1 |
| 18 | Automatic design and optimization of wind turbine blades显示文摘 | Díaz Casás V Lopez Pea F Duro R J | 2006 | Computer Society2006，，1： | 1 |
| 19 | Scaffolds for articular cartilage repair annals of biomedical egineering显示文摘 | Sally R Frenkel PE Di Cesare | 2004 | Annals of Biomedical Engineering2004，32，： | 1 |
| 20 | A retrospective study of the potential complications during alveolar distraction osteogenesis in 55 patients显示文摘 | Mazzonetto R Allais M Manrette PE | 2007 | Int J Oral Maxillofac Surg2007，36，1： | 1 |
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