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| 1 | Treatment strategies for colorectal carcinoma with synchronous liver metastases: Which way to go?显示文摘AIM: To offer an up-to-date review of all availabletreatment strategies for patients with synchronous colorectal liver metastases(CLM).METHODS: A comprehensive literature search was performed to identify articles related to the management of patients with synchronous CLM. A search of the electronic databases PubMed, MEDLINE, and Google Scholar was conducted in September 2014.The following search terms were used: synchronous colorectal liver metastases, surgery, stage Ⅳ colorectal cancer, liver-first approach, and up-front hepatectomy.These terms were employed in various combinations to maximize the search. Only articles written in English were included. Particular attention was devoted to studies and review articles that were published within the last six years(2009-2014). Additional searches of the cited references from primary articles were performed to further improve the review. The full texts of all relevant articles were accessed by two independent reviewers.RESULTS: Poor long-term outcomes of patients with synchronous CLM managed by a traditional treatment strategy have led to questions about the timing and sequence of possible therapeutic interventions. Thus,alternative paradigms called reverse strategies have been proposed. Presently, there are four treatment strategies available:(1) primary first approach(or traditional approach) comprises resection of the primary colorectal tumor followed by chemotherapy;subsequent liver resection is performed 3-6 mo after colorectal resection(provided that CLM are still resectable);(2) simultaneous resection of the primary colorectal tumor and CLM during a single operation presents intriguing options for a highly select group of patients, which can be associated with significant postoperative morbidity;(3) liver-first(or chemotherapy-first) approach comprises preoperative chemotherapy(3-6 cycles) followed by liver resection,adjuvant chemotherapy, and resection of the primary colorectal tumor(it is best suited for patients withasymptomatic primary tumors and initially unresectable or marginally resectable CLM); and(4) up-front hepatectomy(or 'true' liver-first approach) includes liver resection followed by adjuvant chemotherapy,colorectal resection, and adjuvant chemotherapy(strategy can be offered to patients with asymptomatic primary tumors and initially resectable CLM).CONCLUSION: None of the aforementioned strategies appears inferior. It is necessary to establish individual treatment plans in multidisciplinary team meetings through careful appraisal of all strategies. | Peter Ihnát Petr Vávra Pavel Zonca | 2015 | World Journal of Gastroenterology2015,21,22: | 10 |
| 2 | High‑throughput sequencing view on the magnitude of global fungal diversity显示文摘High-throughput DNA sequencing has dramatically transformed several areas of biodiversity research including mycol-ogy.Despite limitations,high-throughput sequencing is nowadays a predominant method to characterize the alpha and beta diversity of fungal communities.Across the papers utilizing high-throughput sequencing approaches to study natural habitats in terrestrial ecosystems worldwide,>200 studies published until 2019 have generated over 250 million sequences of the primary mycological metabarcoding marker,the nuclear ribosomal internal transcribed spacer 2(ITS2).Here we show that at a 97%sequence similarity threshold,the total richness of non-singleton fungal taxa across the studies published so far is 1.08 million,mostly Ascomycota(56.8%of the taxa)and Basidiomycota(36.7%of the taxa).The Chao-1 estimate of the total extant fungal diversity based on this dataset is 6.28 million taxa,representing a conservative estimate of global fungal species richness.Soil and litter represent the habitats with the highest alpha diversity of fungi followed by air,plant shoots,plant roots and deadwood with Chao-1 predictions,for samples containing 5000 sequences,of 1219,569,392,228,215 and 140 molecular species,respectively.Based on the high-throughput sequencing data,the highest proportion of unknown fungal species is associated with samples of lichen and plant tissues.When considering the use of high-throughput sequenc-ing for the estimation of global fungal diversity,the limitations of the method have to be taken into account,some of which are sequencing platform-specific while others are inherent to the metabarcoding approaches of species representation.In this respect,high-throughput sequencing data can complement fungal diversity predictions based on methods of traditional mycology and increase our understanding of fungal biodiversity. | Petr Baldrian TomášVětrovský Clémentine Lepinay Petr Kohout | 2022 | Fungal Diversity2022,,3: | 8 |
| 3 | Sensitivity analysis of parameters and contrasting performance of ground filtering algorithms with UAV photogrammetry-based and LiDAR point clouds显示文摘Most ground filtering algorithms are primarily designed for airborne LiDAR point cloud processing and their successful use in identifying ground points from photogrammetric point clouds remains questionable.We compared six ground filtering algorithms implemented in Metashape,ArcGIS,CloudCompare,LAStools,and PDAL.We used UAV photogrammetry-based(acquired under leaf-off conditions)and airborne LiDAR(leaf-on)point clouds of the same area to:(i)compare accuracy of generated DTMs;(ii)evaluate the effect of vegetation density and terrain slope on filtering accuracy;and(iii)assess which algorithm parameters have the greatest effect on the filtering accuracy.Our results show that the performance of filtering algorithms was affected by the point cloud type,terrain slope and vegetation cover.The results were generally better for LiDAR(RMSE 0.13–0.19 m)than for photogrammetric(RMSE 0.19–0.23 m)point clouds.The behavior in varying vegetation and terrain conditions was consistent for LiDAR point clouds.However,when applied on photogrammetric point clouds,the algorithms’behavior was inconsistent,especially in areas of steep slope(except for the Progressive Triangulated Irregular Network in LAStools).Parameters related to the selection of the initial minimum elevation ground points were the most influential in all algorithms and point clouds. | Petr Klápště Michal Fogl Vojtěch Barták Kateřina Gdulová Rudolf Urban Vítězslav Moudrý | 2020 | International Journal of Digital Earth2020,13,12: | 2 |
| 4 | Degradation of cellulose by basidiomycetous fungi 显示文摘 | PETR BALDRIAN V V K | 2008 | FEMS Microbiol Rev2008,32,3: | 1 |
| 5 | Pharmacological activities of natural triterpenoids and their therapeutic implications显示文摘 | PETR D MARIAN H DAVID V | 2006 | J Nat Prod2006,23,3: | 1 |
| 6 | Effect of different cooking methods on lipid oxidation and formation of free cholesterol oxidation products(COPs)in Latissimusdorsimuscle of Iberian pigs显示文摘 | Broncano JM Petrón MJ Parra V | 2009 | Meat Science2009,83,: | 1 |
| 7 | Transesophageal Echocardiography in the detection of potential cardiac source of embolismin stroke patients显示文摘 | Petr P Christopher V | 1991 | Stroke1991,22,6: | 1 |
| 8 | Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HE-60 cells 显示文摘 | Jiri V Petr D Jaroslav V | 2008 | Toxicology in Vitro2008,22,4: | 1 |
| 9 | Effect of different cooking methods on lipid oxidation and formation of free cholesterol oxidation products(COPs)in Latissimusdorsi muscle of Iberian pigs显示文摘 | Broncano J M Petrón M J Parra V | 2009 | Meat Science2009,83,3: | 1 |
| 10 | Free plasma metanephrines as a screening test for pheochromocytoma in low-risk patients显示文摘 | Jan Václavík David Stejskal Bo?ek La?ňák Marie Lazárová Libor Jedelsky Lenka Kadalová Marie Jano?ová Zdeněk Fry?ák Petr Vl?ek | 2007 | Journal of Hypertension2007,,7: | 1 |
| 11 | Heterogeneous effects in the droplet nucleation process显示文摘 | Petr V Kolovrantnik M | 2000 | Power Plant Chemistry2000,2,10: | 1 |
| 12 | A review of the features and analyses of the solid electrolyte interphase in Li-ion batteries显示文摘 | PALLAVI V PASCAL M PETR N | | 0,,22: | 1 |
| 13 | Changes of Serum Calcium, Magnesium and Parathyroid Hormone Induced by Hemodialysis with Citrate- Enriched Dialysis Solution 显示文摘 | Roman Petr M Jaroslava V | 2015 | Kidney Blood Press Res2015,40,1: | 1 |
| 14 | 查看详情显示文摘 | Tskhakaya D Kuhn S Petr(z)ilka V | | 0,,: | 1 |
| 15 | Backbone colorings for graphs:Tree and path backbones 显示文摘 | HAJO B FEDOR V F PETR A G GERHARD J W | 2007 | Journal of Graph Theory2007,55,2: | 1 |
| 16 | A new selective medium for the isolation of glucose nofi-fermenting Bifidobacteria from hen caeca 显示文摘 | Ratta V Petr J | 2000 | J Microbiol Meth- ods2000,43,: | 1 |
| 17 | Adsorption of atmospherically relevant gases at the air/water interface: free energy profiles of aqueous solvation of N2, O2, O3, OH, H2O, HO2, and H2O2显示文摘 | Robert V Petr M Mucha M | 2004 | The Journal Physical Chemistry A2004,108,11: | 1 |
| 18 | Modelling of the droplet size distribution in a low-pressure steam turbine显示文摘 | Petr V Kolovratnik M | | 0,,: | 1 |
| 19 | Kinetic models for volatile chlorinated hydrocarbons removal by zero-valent iron显示文摘 | VACLAV J PETR V JANA B | 2004 | Chemosphere2004,54,7: | 1 |
| 20 | Detection of ICAM-1 in Experimentally Induced Colitis of ICAM-1-deficient and Wild-type Mice: An Immunohistochemical Study显示文摘 | Farid Bendjelloul Pavel Rossmann Petr Maly Václav Mandys Marie Jirkovská Ludmila Proke?ová Ludmila Tu?ková Helena Tlaskalová-Hogenová | 2000 | The Histochemical Journal2000,,12: | 1 |